{
  "id": 23066,
  "label": "gastric non-hodgkin lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0042493",
  "properties": {
    "xrefs": [
      "GARD:0000089",
      "MEDGEN:232549",
      "NCIT:C27235",
      "SCTID:448709005",
      "UMLS:C1333784"
    ],
    "synonyms": [
      "gastric non-Hodgkin lymphoma",
      "gastric non-Hodgkin's lymphoma",
      "non-Hodgkin lymphoma of stomach",
      "non-Hodgkin's lymphoma of stomach",
      "non-Hodgkin's lymphoma of the stomach",
      "primary gastric non-Hodgkin's lymphoma",
      "stomach non-Hodgkin lymphoma",
      "lymphoma, gastric non Hodgkins type",
      "non-Hodgkins gastric lymphoma",
      "stomach lymphoma, non-Hodgkins type"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "An extranodal non-Hodgkin lymphoma that arises from the stomach with the bulk of the mass located in the stomach. The vast majority of cases are diffuse large B-cell lymphomas and B-cell lymphomas of the mucosa-associated lymphoid tissue."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 3314,
      "label": "gastric lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3312,
        6479
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10540",
          "GARD:0022871",
          "ICD9:202.83",
          "MEDGEN:87603",
          "NCIT:C4636",
          "NORD:1607",
          "SCTID:276811008",
          "UMLS:C0349532"
        ],
        "synonyms": [
          "Primary Gastric Lymphoma",
          "gastric lymphoma",
          "lymphoma of stomach",
          "lymphoma of the stomach",
          "primary gastric lymphoma",
          "stomach lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An extranodal lymphoma that arises from the stomach with the bulk of the mass located in the stomach. The vast majority of cases are diffuse large B-cell lymphomas and B-cell lymphomas of the mucosa-associated lymphoid tissue."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001059"
    },
    {
      "id": 18836,
      "label": "non-Hodgkin lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060060",
          "EFO:0005952",
          "ICDO:9591/3",
          "MEDGEN:6160",
          "MESH:D008228",
          "MedDRA:10029547",
          "NCIT:C3211",
          "ONCOTREE:NHL",
          "Orphanet:547",
          "UMLS:C0024305"
        ],
        "synonyms": [
          "NHL",
          "non-Hodgkin lymphoma",
          "non-Hodgkin's lymphoma",
          "non-Hodgkin's lymphoma (NHL)",
          "non-Hodgkins lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Distinct from Hodgkin lymphoma both morphologically and biologically, non-Hodgkin lymphoma (NHL) is characterized by the absence of Reed-Sternberg cells, can occur at any age, and usually presents as a localized or generalized lymphadenopathy associated with fever and weight loss. The clinical course varies according to the morphologic type. NHL is clinically classified as indolent, aggressive, or having a variable clinical course. NHL can be of B-or T-/NK-cell lineage."
      },
      "child_count": 10,
      "reference_id": "MONDO:0018908"
    }
  ],
  "children": [
    {
      "id": 7778,
      "label": "gastric mantle cell lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3028,
        18808,
        23066
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000272",
          "GARD:0024339",
          "MEDGEN:234300",
          "NCIT:C27440",
          "UMLS:C1333780"
        ],
        "synonyms": [
          "gastric mantle cell lymphoma",
          "mantle cell lymphoma of stomach",
          "mantle cell lymphoma of the stomach",
          "stomach mantle cell lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A mantle cell lymphoma that affects the stomach. It may arise as a solitary mass or it may be a component of multifocal lymphomatous polyposis of the gastrointestinal tract. It usually has an aggressive clinical course."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006225"
    },
    {
      "id": 7779,
      "label": "gastric mucosa-associated lymphoid tissue lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7558,
        9011,
        18536,
        23066
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000274",
          "GARD:0024340",
          "MEDGEN:232547",
          "NCIT:C5266",
          "UMLS:C1333782"
        ],
        "synonyms": [
          "MALT lymphoma of stomach",
          "MALT lymphoma of the stomach",
          "MALToma of stomach",
          "MALToma of the stomach",
          "gastric MALT lymphoma",
          "gastric MALToma",
          "gastric mucosa-associated lymphoid tissue lymphoma",
          "primary MALT lymphoma of stomach",
          "primary MALT lymphoma of the stomach",
          "primary gastric B-cell MALT lymphoma",
          "primary gastric MALT lymphoma",
          "stomach MALT lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A low grade, indolent B-cell lymphoma, usually associated with Helicobacter pylori infection. Morphologically it is characterized by a dense mucosal atypical lymphocytic (centrocyte-like cell) infiltrate with often prominent lymphoepithelial lesions and plasmacytic differentiation. Approximately 40% of gastric MALT lymphomas carry the t(11;18)(q21;q21). Such cases are resistant to Helicobacter pylori therapy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006226"
    }
  ],
  "roots": [
    {
      "id": 3314,
      "label": "gastric lymphoma"
    },
    {
      "id": 18836,
      "label": "non-Hodgkin lymphoma"
    }
  ]
}