{
  "id": 23099,
  "label": "familial osteosclerosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0042973",
  "properties": {
    "synonyms": [
      "hereditary osteosclerosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      }
    ],
    "definition": "An instance of osteosclerosis that is caused by an inherited modification of the individual's genome."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 4938,
      "label": "osteosclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3151
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4254",
          "MEDGEN:10502",
          "MESH:D010026",
          "NANDO:2201022",
          "NCIT:C41236",
          "SCTID:49347007",
          "UMLS:C0029464",
          "icd11.foundation:2061303143"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Abnormally high bone density."
      },
      "child_count": 3,
      "reference_id": "MONDO:0002933"
    },
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    }
  ],
  "children": [
    {
      "id": 8588,
      "label": "axial osteomalacia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23099
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080039",
          "GARD:0008431",
          "MEDGEN:354730",
          "MESH:C537791",
          "OMIM:109130",
          "UMLS:C1862372"
        ],
        "synonyms": [
          "axial osteomalacia",
          "atypical osteomalacia involving the axial skeleton"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0007181"
    },
    {
      "id": 16306,
      "label": "craniometaphyseal dysplasia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23099
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080033",
          "GARD:0015013",
          "ICD9:756.89",
          "MEDGEN:82702",
          "NANDO:2201366",
          "NORD:1013",
          "OMIMPS:123000",
          "Orphanet:1522",
          "SCTID:36601008",
          "UMLS:C0265292",
          "icd11.foundation:305860050"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Craniometaphyseal dysplasia (CMD) is a very rare genetic bone disease characterized by progressive diffuse hyperostosis of cranial bones causing facial dysmorphism and functional repercussions, and metaphyseal widening of long bones."
      },
      "child_count": 4,
      "reference_id": "MONDO:0015465"
    },
    {
      "id": 17540,
      "label": "osteopetrosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        18360,
        23099
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13533",
          "GARD:0004155",
          "HP:0011002",
          "ICD10CM:Q78.2",
          "ICD9:756.52",
          "MEDGEN:18223",
          "MESH:D010022",
          "MedDRA:10031280",
          "NANDO:1200998",
          "NANDO:2201013",
          "NCIT:C26840",
          "NORD:1538",
          "Orphanet:2781",
          "SCTID:1926006",
          "UMLS:C0029454",
          "icd11.foundation:1498426606"
        ],
        "synonyms": [
          "Albers-Schonberg disease",
          "marble bone disease",
          "marble bones",
          "osteopetrosis",
          "osteopetrosis (disease)",
          "Albers-Schoenberg disease",
          "osteopetroses",
          "osteopetrosis and related disorders",
          "osteosclerosis fragilis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          }
        ],
        "definition": "Osteopetrosis, also known as marble bone disease, is a descriptive term that refers to a group of rare, heritable disorders of the skeleton characterized by increased bone density on radiographs."
      },
      "child_count": 22,
      "reference_id": "MONDO:0017198"
    }
  ],
  "roots": [
    {
      "id": 4938,
      "label": "osteosclerosis"
    },
    {
      "id": 5714,
      "label": "hereditary disease"
    }
  ]
}