{
  "id": 23119,
  "label": "acute posterior multifocal placoid pigment epitheliopathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0043089",
  "properties": {
    "xrefs": [
      "GARD:0002183",
      "ICD10CM:H30.14",
      "MEDGEN:56348",
      "NORD:1101",
      "SCTID:89188001",
      "UMLS:C0154884",
      "icd11.foundation:2036282532"
    ],
    "synonyms": [
      "Epitheliopathy, Acute Posterior Multifocal Placoid Pigment",
      "acute posterior multifocal placoid pigment epitheliopathy",
      "AMPPE",
      "APMPPE",
      "acute multifocal placoid pigment epitheliopathy",
      "acute placoid pigment epitheliopathy",
      "amppe - acute multifocal placoid pigment epitheliopathy",
      "apmppe",
      "epitheliopathy, acute posterior multifocal placoid pigment",
      "multifocal placoid pigment epitheliopathy",
      "pigment epitheliopathy, disseminated retinitis and retinochoroiditis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is an acquired, inflammatory eye condition affecting the retina, retinal pigment epithelium (pigmented layer of the retina), and choroid. It usually affects both eyes and is characterized by multiple, yellow-white lesions in the back of the eye. The condition can significantly impair visual acuity if the macula is involved. APMPPE typically resolves on its own in weeks to months. While the cause is unknown, about a third of cases appear to develop after a flu-like illness. Non-ocular symptoms are uncommon, but cerebral vasculitis can be present and may cause permanent and/or severe neurological complications."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 20092,
      "label": "acute disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24492
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:1738",
          "MESH:D000208",
          "SCTID:2704003",
          "UMLS:C0001314"
        ],
        "synonyms": [
          "acute disease",
          "acute diseases",
          "disease, acute"
        ],
        "definition": "Disease having a short and relatively severe course."
      },
      "child_count": 119,
      "reference_id": "MONDO:0020683"
    },
    {
      "id": 21276,
      "label": "multifocal choroiditis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3514
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009824",
          "MEDGEN:288551",
          "MESH:C537374",
          "MESH:D000080364",
          "SCTID:414783007",
          "UMLS:C1533060",
          "icd11.foundation:1197219411"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Multifocal choroiditis (MFC) is an inflammatory disorder characterized by swelling of the eye (called uveitis) and multiple lesions in the choroid, a layer of blood vessels between the white of the eye and the retina. Symptoms include blurry vision, floaters, sensitivity to light, blind spots and mild eye discomfort. Though the cause is unknown, multifocal choroiditis is seen most frequently in women ages 20 to 60, and usually affects both eyes. MFC is generally treated with steroid medication that can be taken orally or injected into the eye. Multifocal choroiditis is a chronic condition, thus symptoms may return or worsen even after successful treatment."
      },
      "child_count": 1,
      "reference_id": "MONDO:0023833"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 20092,
      "label": "acute disease"
    },
    {
      "id": 21276,
      "label": "multifocal choroiditis"
    }
  ]
}