{
  "id": 23165,
  "label": "neurovascular disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0043218",
  "properties": {
    "xrefs": [
      "MEDGEN:857738",
      "NCIT:C117007",
      "UMLS:C3898144"
    ],
    "synonyms": [
      "disease of nervous system vasculature",
      "nervous system disorder of vasculature",
      "neurovascular disorder",
      "vasculature nervous system disorder"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A disorder of the nervous system related to a vascular etiology."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 29,
  "parents": [
    {
      "id": 6799,
      "label": "nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:863",
          "EFO:0000618",
          "ICD10CM:G00-G99",
          "ICD9:349.89",
          "ICD9:349.9",
          "MEDGEN:14336",
          "MESH:D009422",
          "NCIT:C26835",
          "SCTID:118940003",
          "UMLS:C0027765",
          "Wikipedia:Nervous_system_disease"
        ],
        "synonyms": [
          "disease of nervous system",
          "disease or disorder of nervous system",
          "disorder of nervous system",
          "nervous system disease",
          "nervous system disease or disorder",
          "nervous system disorder",
          "neurologic disease",
          "neurologic disorder",
          "neurological disease",
          "neurological disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves."
      },
      "child_count": 72,
      "reference_id": "MONDO:0005071"
    },
    {
      "id": 7065,
      "label": "vascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6736
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:178",
          "EFO:0004264",
          "ICD10CM:I00-I99",
          "ICD10CM:I70-I79",
          "ICD9:442.9",
          "MEDGEN:22621",
          "MESH:D014652",
          "NANDO:2100294",
          "NCIT:C35117",
          "SCTID:27550009",
          "UMLS:C0042373"
        ],
        "synonyms": [
          "disease of vasculature",
          "disease or disorder of vasculature",
          "disorder of vasculature",
          "vascular disorder",
          "vasculature disease",
          "vasculature disease or disorder",
          "vasculopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A general term used to describe any disease affecting blood vessels]. It includes vascular abnormalities caused by degenerative, metabolic and inflammatory conditions, embolic diseases, coagulative disorders, and functional disorders such as posteri or reversible encephalopathy syndrome."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005385"
    }
  ],
  "children": [
    {
      "id": 3745,
      "label": "retinal ischemia",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6784,
        6979,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12510",
          "ICD10CM:H35.82",
          "ICD9:362.84",
          "MEDGEN:102372",
          "SCTID:26468004",
          "UMLS:C0162291"
        ],
        "synonyms": [
          "ischaemic disease of retina",
          "ischemic disease of retina",
          "retina ischaemic disease",
          "retina ischemic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A ischemic disease that involves the retina."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001538"
    },
    {
      "id": 3860,
      "label": "retinal dystrophies primarily involving Bruch's membrane",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4072,
        19000,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13227",
          "GARD:0022986",
          "ICD9:362.77",
          "MEDGEN:1720702",
          "UMLS:C0154866"
        ],
        "synonyms": [
          "Bruch's membrane inherited retinal dystrophy",
          "inherited retinal dystrophy of Bruch's membrane"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A retinal dystrophy with etiology arising from Bruch's membrane, the site of drusen generation."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001666"
    },
    {
      "id": 4419,
      "label": "retinal vascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6979,
        7202,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2462",
          "ICD9:362.13",
          "MEDGEN:57824",
          "NCIT:C35170",
          "SCTID:57534004",
          "UMLS:C0154833"
        ],
        "synonyms": [
          "retinal vascular disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Retinal damage resulting from diminished blood flow/oxygenation due to abnormalities of the retinal vessels. Causes include hypertension, diabetes, thrombosis, embolism, and hemorrhage."
      },
      "child_count": 36,
      "reference_id": "MONDO:0002311"
    },
    {
      "id": 4728,
      "label": "choroid plexus cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        4729,
        17175,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3540",
          "EFO:0007206",
          "GARD:0023212",
          "MEDGEN:138053",
          "NCIT:C4533",
          "UMLS:C0346289"
        ],
        "synonyms": [
          "choroid plexus neoplasm",
          "tumor of choroid plexus",
          "tumour of choroid plexus",
          "tumour of the choroid plexus",
          "cancer of choroid plexus",
          "choroid plexus cancer",
          "malignant choroid plexus neoplasm",
          "malignant choroid plexus neoplasms",
          "malignant choroid plexus tumor",
          "malignant choroid plexus tumors",
          "malignant choroid plexus tumour",
          "malignant choroid plexus tumours",
          "malignant neoplasm of choroid plexus",
          "malignant neoplasm of the choroid plexus",
          "malignant tumor of choroid plexus",
          "malignant tumor of the choroid plexus",
          "malignant tumour of choroid plexus",
          "malignant tumour of the choroid plexus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant neoplasm involving the choroid plexus"
      },
      "child_count": 8,
      "reference_id": "MONDO:0002681"
    },
    {
      "id": 4995,
      "label": "cavernous sinus meningioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4997,
        6420,
        20321,
        21452,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4435",
          "GARD:0023317",
          "MEDGEN:232034",
          "NCIT:C5268",
          "UMLS:C1332865"
        ],
        "synonyms": [
          "cavernous sinus meningioma (disease)",
          "meningioma (disease) of cavernous sinus",
          "meningioma of cavernous sinus",
          "meningioma of the cavernous sinus"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A meningioma that affects the cavernous sinus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002996"
    },
    {
      "id": 5014,
      "label": "central nervous system angiosarcoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4336,
        17394,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4504",
          "GARD:0023329",
          "MEDGEN:272441",
          "NCIT:C5450",
          "UMLS:C1332875"
        ],
        "synonyms": [
          "CNS angiosarcoma",
          "CNS hemangiosarcoma",
          "angiosarcoma (disease) of central nervous system",
          "angiosarcoma of CNS",
          "angiosarcoma of central nervous system",
          "angiosarcoma of the CNS",
          "angiosarcoma of the central nervous system",
          "central nervous system angiosarcoma",
          "central nervous system angiosarcoma (disease)",
          "central nervous system hemangiosarcoma",
          "hemangiosarcoma of CNS",
          "hemangiosarcoma of central nervous system",
          "hemangiosarcoma of the CNS",
          "hemangiosarcoma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A malignant vascular neoplasm arising from the brain, spinal cord or meninges."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003021"
    },
    {
      "id": 5188,
      "label": "central nervous system hemangioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3033,
        7994,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:501",
          "MEDGEN:272703",
          "NCIT:C7004",
          "UMLS:C1333957"
        ],
        "synonyms": [
          "central nervous system hemangioma",
          "hemangioma of CNS",
          "hemangioma of central nervous system",
          "hemangioma of the CNS",
          "hemangioma of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A hemangioma arising from the brain and spinal cord."
      },
      "child_count": 6,
      "reference_id": "MONDO:0003241"
    },
    {
      "id": 5281,
      "label": "central nervous system vasculitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        18813,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:525",
          "GARD:0023462",
          "MEDGEN:148408",
          "MESH:D020293",
          "NCIT:C84622",
          "UMLS:C0751878"
        ],
        "synonyms": [
          "central nervous system vasculitis",
          "vasculitis of central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Vasculitis affecting the blood vessels of the brain and/or spinal cord."
      },
      "child_count": 15,
      "reference_id": "MONDO:0003346"
    },
    {
      "id": 6640,
      "label": "choroidal sclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4072,
        6639,
        7208,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:980",
          "ICD9:363.4",
          "ICD9:363.40",
          "MEDGEN:137998",
          "MESH:C535358",
          "SCTID:406446000",
          "UMLS:C0344297"
        ],
        "synonyms": [
          "choroidal degenerations",
          "neurodegenerative disease of optic choroid",
          "optic choroid neurodegenerative disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A neurodegenerative disease that involves the optic choroid."
      },
      "child_count": 16,
      "reference_id": "MONDO:0004885"
    },
    {
      "id": 6973,
      "label": "migraine disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7209,
        17523,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6364",
          "ICD10CM:G43",
          "ICD9:346",
          "ICD9:346.9",
          "MEDGEN:57451",
          "MESH:D008881",
          "NCIT:C89715",
          "UMLS:C0149931",
          "icd11.foundation:669367341"
        ],
        "synonyms": [
          "migraine",
          "migraine headache"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A common, severe type of vascular headache often associated with increased sympathetic activity, resulting in nausea, vomiting, and light sensitivity."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005277"
    },
    {
      "id": 7833,
      "label": "malignant jugulotympanic paraganglioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4233,
        4265,
        4753,
        6420,
        20305,
        20310,
        20329,
        21452,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024363",
          "MEDGEN:87584",
          "NCIT:C4623",
          "UMLS:C0347856"
        ],
        "synonyms": [
          "cancer of jugular body",
          "jugular body cancer",
          "malignant glomus jugulare neoplasm",
          "malignant glomus jugulare tumor",
          "malignant glomus jugulare tumour",
          "malignant jugular body neoplasm",
          "malignant jugulotympanic paraganglioma",
          "malignant neoplasm of glomus jugulare",
          "malignant neoplasm of jugular body",
          "malignant neoplasm of the glomus jugulare",
          "malignant tumor of glomus jugulare",
          "malignant tumor of the glomus jugulare",
          "malignant tumour of glomus jugulare",
          "malignant tumour of the glomus jugulare"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A jugulotympanic paraganglioma that metastasizes to other anatomic sites."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006291"
    },
    {
      "id": 8163,
      "label": "choroid cancer",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4233,
        4710,
        20462,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12759",
          "ICD10CM:C69.3",
          "ICD9:190.6",
          "MEDGEN:57794",
          "MESH:D002830",
          "MedDRA:10057405",
          "NCIT:C3566",
          "SCTID:363466008",
          "UMLS:C0153630"
        ],
        "synonyms": [
          "choroid neoplasm",
          "choroidal tumor",
          "choroidal tumour",
          "cancer of optic choroid",
          "malignant choroid neoplasm",
          "malignant choroid tumor",
          "malignant choroid tumour",
          "malignant neoplasm of choroid",
          "malignant neoplasm of optic choroid",
          "malignant neoplasm of the choroid",
          "malignant optic choroid neoplasm",
          "malignant tumor of choroid",
          "malignant tumor of the choroid",
          "malignant tumour of choroid",
          "malignant tumour of the choroid",
          "optic choroid cancer"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A malignant neoplasm involving the optic choroid."
      },
      "child_count": 4,
      "reference_id": "MONDO:0006700"
    },
    {
      "id": 8258,
      "label": "intracranial hypertension",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6776,
        7209,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9428",
          "EFO:1000992",
          "MEDGEN:56241",
          "MESH:D019586",
          "MedDRA:10022764",
          "UMLS:C0151740"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A finding characterized by increased cerebrospinal fluid pressure within the skull."
      },
      "child_count": 6,
      "reference_id": "MONDO:0006810"
    },
    {
      "id": 9251,
      "label": "microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2903,
        3394,
        4370,
        19000,
        19154,
        23165,
        24226
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060349",
          "GARD:0003622",
          "MEDGEN:320559",
          "MESH:C537711",
          "OMIM:152950",
          "Orphanet:2526",
          "UMLS:C1835265"
        ],
        "synonyms": [
          "KIF11-associated disorder",
          "MCLMR",
          "MLCRD",
          "MLCRD syndrome",
          "lymphedema, microcephaly and chorioretinopathy syndrome",
          "microcephaly with or without chorioretinopathy, lymphedema, or intellectual disability",
          "microcephaly with or without chorioretinopathy, lymphedema, or mental retardation",
          "microcephaly, lymphedema, chorioretinal dysplasia syndrome",
          "KIF11 disease",
          "microcephaly and chorioretinopathy with or without mental retardation, autosomal dominant"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A microcephaly caused by a mutation in KIF11 gene and follows autosomal dominant inheritance. It is characterized by variable expression of microcephaly, ocular disorders including chorioretinopathy, congenital lymphedema of the lower limbs, and mild to moderate intellectual disability."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007918"
    },
    {
      "id": 9253,
      "label": "lymphatic malformation 5",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2944,
        19154,
        23165,
        23452
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070213",
          "GARD:0003324",
          "MEDGEN:1648463",
          "MESH:C562467",
          "MedDRA:10027138",
          "OMIM:153200",
          "Orphanet:90186",
          "SCTID:400040008",
          "UMLS:C4746631"
        ],
        "synonyms": [
          "LMPH2",
          "Meige disease",
          "Meige lymphedema",
          "hereditary lymphedema type II",
          "late-onset primary lymphedema",
          "lymphedema hereditary type 2",
          "lymphedema praecox",
          "lymphedema, hereditary, II",
          "lymphedema, late-onset"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A frequent form of late-onset, primary lymphedema characterized by lower limb lymphedema typically developing during puberty."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007920"
    },
    {
      "id": 10970,
      "label": "Norman-Roberts syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        16115,
        19154,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060902",
          "GARD:0016780",
          "MEDGEN:163213",
          "OMIM:257320",
          "Orphanet:89844",
          "SCTID:717977003",
          "UMLS:C0796089",
          "icd11.foundation:164166454"
        ],
        "synonyms": [
          "Microlissencephaly type A",
          "Norman-Roberts syndrome",
          "lissencephaly 2",
          "lissencephaly 2 (Norman-Roberts type)",
          "lissencephaly syndrome, Norman-Roberts type",
          "LIS2",
          "Norman Roberts lissencephaly syndrome",
          "lissencephaly syndrome Norman-Roberts type"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Lissencephaly syndrome, Norman-Roberts type is characterized by the association of lissencephaly type I with craniofacial anomalies (severe microcephaly, a low sloping forehead, a broad and prominent nasal bridge and widely set eyes) and postnatal growth retardation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009760"
    },
    {
      "id": 11006,
      "label": "ornithine aminotransferase deficiency",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4072,
        17673,
        19000,
        19748,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1415",
          "GARD:0006556",
          "MEDGEN:6695",
          "MESH:D015799",
          "NANDO:2200484",
          "NANDO:2200486",
          "NCIT:C84744",
          "OMIM:258870",
          "Orphanet:414",
          "UMLS:C0018425"
        ],
        "synonyms": [
          "GACR",
          "HOGA",
          "gyrate atrophy",
          "gyrate atrophy of choroid and retina with or without ornithinemia",
          "hoga",
          "hyperornithinemia",
          "hyperornithinemia-gyrate atrophy of choroid and retina syndrome",
          "ornithine aminotransferase deficiency",
          "Fuchs atrophia gyrata chorioideae et retinae",
          "Fuchs gyrate atrophy",
          "Fuchs gyrate atrophy of the choroid and retina",
          "Girate atrophy of the retina",
          "OAT deficiency",
          "OKT deficiency",
          "Oat deficiency",
          "Okt deficiency",
          "Ornithinemia",
          "gyrate atrophy of choroid and retina",
          "hyperornithinemia with gyrate atrophy of choroid and retina",
          "ornithine Keto acid aminotransferase deficiency",
          "ornithine ketoacid aminotransferase deficiency",
          "ornithine-Delta-aminotransferase deficiency"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A very rare inherited retinal dystrophy characterized by progressive chorioretinal atrophy, myopia and early cataract."
      },
      "child_count": 0,
      "reference_id": "MONDO:0009796"
    },
    {
      "id": 11711,
      "label": "choroideremia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2902,
        4072,
        19000,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9821",
          "GARD:0006061",
          "ICD10CM:H31.21",
          "ICD9:363.55",
          "MEDGEN:944",
          "MESH:D015794",
          "MedDRA:10008791",
          "NCIT:C34469",
          "NORD:932",
          "OMIM:303100",
          "Orphanet:180",
          "SCTID:75241009",
          "UMLS:C0008525",
          "icd11.foundation:217923263"
        ],
        "synonyms": [
          "CHM",
          "Tapetochoroidal dystrophy",
          "choroideremia",
          "progressive choroidal atrophy",
          "TCD",
          "Tapetochoroidal dystrophy, progressive",
          "choroidal sclerosis",
          "progressive tapetochoroidal dystrophy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Choroideremia (CHM) is an X-linked chorioretinal dystrophy characterized by progressive degeneration of the choroid, retinal pigment epithelium (RPE) and retina."
      },
      "child_count": 8,
      "reference_id": "MONDO:0010557"
    },
    {
      "id": 12183,
      "label": "cerebrovascular disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7209,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6713",
          "EFO:0003763",
          "ICD10CM:I60-I69",
          "ICD9:430-438",
          "ICD9:434.91",
          "ICD9:437.8",
          "ICD9:437.9",
          "MEDGEN:858",
          "MESH:D002561",
          "NCIT:C2938",
          "SCTID:62914000",
          "UMLS:C0007820",
          "icd11.foundation:843843448"
        ],
        "synonyms": [
          "cerebrovascular disease",
          "cerebrovascular disorder",
          "CVA",
          "CVA (cerebral vascular accident)",
          "cerebral infarction",
          "cerebrovascular accident",
          "stroke"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction."
      },
      "child_count": 48,
      "reference_id": "MONDO:0011057"
    },
    {
      "id": 14174,
      "label": "choroidal dystrophy, central areolar 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        10240,
        23165,
        29285
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015615",
          "MEDGEN:442696",
          "MESH:C567750",
          "OMIM:613105",
          "UMLS:C2751290"
        ],
        "synonyms": [
          "PRPH2 central areolar choroidal dystrophy",
          "central areolar choroidal dystrophy caused by mutation in PRPH2",
          "choroidal dystrophy, central areolar 2",
          "choroidal dystrophy, central areolar type 2",
          "CACD2",
          "macular dystrophy, progressive"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any central areolar choroidal dystrophy in which the cause of the disease is a mutation in the PRPH2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013137"
    },
    {
      "id": 16344,
      "label": "trigeminal autonomic cephalalgia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5448,
        17523,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020017",
          "ICD9:339.09",
          "MEDGEN:327950",
          "MESH:D051303",
          "NCIT:C117074",
          "Orphanet:157843",
          "SCTID:449814007",
          "UMLS:C1565172",
          "icd11.foundation:607078588"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A headache disorder characterized by episodes of unilateral, short lasting pain and associated ipsilateral cranial autonomic symptoms."
      },
      "child_count": 12,
      "reference_id": "MONDO:0015530"
    },
    {
      "id": 17196,
      "label": "hemangioblastoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3049,
        4497,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5241",
          "GARD:0008232",
          "ICDO:9161/1",
          "MEDGEN:104929",
          "MESH:D018325",
          "MedDRA:10018813",
          "NCIT:C3801",
          "ONCOTREE:HMBL",
          "Orphanet:252054",
          "UMLS:C0206734"
        ],
        "synonyms": [
          "angioblastoma",
          "capillary hemangioblastoma",
          "hemangioblastoma",
          "HMBL"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Hemangioblastoma is a rare, benign, highly vascularized tumor of the central nervous system, most often located in the cerebellum or spinal cord, presenting in adulthood and manifesting with dizziness, nausea, malaise, headache, bladder or bowel dysfunction, numbness, weakness and pain in the upper or lower extremities, and often associated with von Hippel-Lindau disease (VHL). Exceptional cases of hemangioblastoma arising outside of the central nervous system have been reported."
      },
      "child_count": 9,
      "reference_id": "MONDO:0016748"
    },
    {
      "id": 18820,
      "label": "Wyburn-Mason syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5091,
        16257,
        19142,
        20682,
        23107,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007900",
          "MEDGEN:120534",
          "MESH:C536752",
          "MedDRA:10048661",
          "NORD:1863",
          "Orphanet:53719",
          "SCTID:6729006",
          "UMLS:C0265321"
        ],
        "synonyms": [
          "CAMS2",
          "Cerebrofacial arteriovenous metameric syndrome type 2",
          "bonnet-Dechaume-Blanc syndrome",
          "Wyburn Mason syndrome",
          "Wyburn Mason's syndrome",
          "arteriovenous aneurysm of mid-brain and retina, facial nevi and mental changes",
          "bonnet-Decaume-Blanc syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Wyburn-Mason syndrome or Bonnet-Dechaume-Blanc syndrome is characterized by the association of arteriovenous malformations of the maxilla, retina, optic nerve, thalamus, hypothalamus and cerebral cortex."
      },
      "child_count": 0,
      "reference_id": "MONDO:0018892"
    },
    {
      "id": 20544,
      "label": "neoplasm of aortic body",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7210,
        20295,
        20321,
        20518,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025316",
          "ICD9:239.7",
          "ICDO:8691/1",
          "MEDGEN:87236",
          "NCIT:C4218",
          "SCTID:127029006",
          "UMLS:C0334417"
        ],
        "synonyms": [
          "aortic body neoplasm",
          "aortic body neoplasm (disease)",
          "aortic body paraganglioma",
          "aortic body tumor",
          "aortic body tumour",
          "aorticopulmonary paraganglioma",
          "neoplasm of aortic body",
          "neoplasm of the aortic body",
          "paraganglioma of aortic body",
          "paraganglioma of the aortic body",
          "tumor of aortic body",
          "tumor of the aortic body",
          "tumour of aortic body",
          "tumour of the aortic body"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant extra-adrenal parasympathetic paraganglioma that arises from paraganglia adjacent to the base of the heart and great vessels."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021389"
    },
    {
      "id": 20608,
      "label": "benign neoplasm of choroid",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3034,
        20462,
        20576,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:D31.3",
          "ICD9:224.6",
          "MEDGEN:57581",
          "NCIT:C3625",
          "SCTID:92059004",
          "UMLS:C0154028",
          "icd11.foundation:809005353"
        ],
        "synonyms": [
          "benign choroid neoplasm",
          "benign choroid tumor",
          "benign choroid tumour",
          "benign neoplasm of the choroid",
          "benign tumor of choroid",
          "benign tumor of the choroid",
          "benign tumour of choroid",
          "benign tumour of the choroid",
          "optic choroid benign neoplasm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A benign neoplasm that involves the optic choroid."
      },
      "child_count": 8,
      "reference_id": "MONDO:0021487"
    },
    {
      "id": 20657,
      "label": "hemangioma of retina",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7994,
        20575,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:228.03",
          "MEDGEN:102307",
          "NCIT:C3634",
          "SCTID:93470007",
          "UMLS:C0154051"
        ],
        "synonyms": [
          "angioma of retina",
          "angioma of the retina",
          "hemangioma of the retina",
          "retina angioma",
          "retina hemangioma",
          "retinal angioma",
          "retinal hemangioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A hemangioma that involves the retina."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021541"
    },
    {
      "id": 20684,
      "label": "eyelid capillary hemangioma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4497,
        5091,
        20682,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:87379",
          "NCIT:C4357",
          "SCTID:231828003",
          "UMLS:C0339110"
        ],
        "synonyms": [
          "capillary angioma of eyelid",
          "capillary angioma of lid",
          "capillary angioma of the eyelid",
          "capillary angioma of the lid",
          "capillary hemangioma of eyelid",
          "capillary hemangioma of lid",
          "capillary hemangioma of the eyelid",
          "capillary hemangioma of the lid",
          "eyelid capillary angioma",
          "eyelid capillary hemangioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A capillary hemangioma arising from the eyelid."
      },
      "child_count": 0,
      "reference_id": "MONDO:0021627"
    },
    {
      "id": 21485,
      "label": "choroidal dystrophy, central areolar, 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        10240,
        23165,
        24168
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025420",
          "MEDGEN:1639900",
          "OMIM:215500",
          "UMLS:C4551884"
        ],
        "synonyms": [
          "GUCY2D central areolar choroidal dystrophy",
          "central areolar choroidal dystrophy caused by mutation in GUCY2D",
          "choroidal dystrophy, central areolar 1",
          "choroidal dystrophy, central areolar, 1",
          "CACD1",
          "choroidal dystrophy, central areolar",
          "choroidal sclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any central areolar choroidal dystrophy in which the cause of the disease is a mutation in the GUCY2D gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0024539"
    },
    {
      "id": 23428,
      "label": "benign choroid plexus neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3034,
        17175,
        20573,
        21330,
        23165
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025906",
          "MEDGEN:87549",
          "NCIT:C8405",
          "SCTID:254943007",
          "UMLS:C0346290",
          "icd11.foundation:1168753028"
        ],
        "synonyms": [
          "benign choroid plexus neoplasm",
          "benign choroid plexus neoplasms",
          "benign choroid plexus tumor",
          "benign choroid plexus tumors",
          "benign choroid plexus tumour",
          "benign choroid plexus tumours",
          "benign neoplasm of choroid plexus",
          "benign neoplasm of the choroid plexus",
          "benign tumor of choroid plexus",
          "benign tumor of the choroid plexus",
          "benign tumour of choroid plexus",
          "benign tumour of the choroid plexus"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 5,
      "reference_id": "MONDO:0044764"
    }
  ],
  "roots": [
    {
      "id": 6799,
      "label": "nervous system disorder"
    },
    {
      "id": 7065,
      "label": "vascular disorder"
    }
  ]
}