{
  "id": 23198,
  "label": "progressive transformation of germinal centers",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0043346",
  "properties": {
    "xrefs": [
      "GARD:0010712",
      "MEDGEN:271018",
      "MESH:C548085",
      "NCIT:C38408",
      "UMLS:C1514481"
    ],
    "synonyms": [
      "progressive transformation of Germinal centers",
      "progressive transformation of Germinal centres",
      "PTGC"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Progressive transformation of germinal centers is a condition in which a lymph node becomes very enlarged (lymphadenopathy). Typically, only one lymph node is affected, though PTGC can involve multiple lymph nodes. Theneck is the most common location of affected lymph nodes, but PTGC may also affect lymph nodes in the groin and armpits. adults are more frequently affected than children, but children have a higher chance of developing PTGC multiple times (recurrence). PTGC is not considered a precancerous condition, though it has been associated with Hodgkin lymphoma."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6792,
      "label": "lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6881,
        16514
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060058",
          "EFO:0000574",
          "ICD9:200.0",
          "ICD9:200.1",
          "ICD9:202.80",
          "ICDO:9590/3",
          "MEDGEN:44223",
          "MESH:D008223",
          "MedDRA:10025310",
          "NANDO:2100004",
          "NCIT:C3208",
          "ONCOTREE:MLYM",
          "Orphanet:223735",
          "SCTID:118600007",
          "UMLS:C0024299"
        ],
        "synonyms": [
          "lymphoma",
          "lymphoma (Hodgkin and non-Hodgkin)",
          "lymphoma (Hodgkin's and non-Hodgkin's)",
          "lymphoma, malignant",
          "lymphomatous",
          "malignant lymphoma",
          "MLYM"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A malignant (clonal) proliferation of B- lymphocytes or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas."
      },
      "child_count": 54,
      "reference_id": "MONDO:0005062"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6792,
      "label": "lymphoma"
    }
  ]
}