{
  "id": 23208,
  "label": "digestive system infectious disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0043424",
  "properties": {
    "xrefs": [
      "NCIT:C35503",
      "SCTID:715852004"
    ],
    "synonyms": [
      "digestive system infection",
      "gastrointestinal infection",
      "gastrointestinal system infection",
      "infection of gastrointestinal tract"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "A viral, bacterial, fungal, or parasitic infectious process that affects the digestive system."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 22,
  "parents": [
    {
      "id": 6151,
      "label": "digestive system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:77",
          "ICD10CM:K00-K95",
          "ICD9:520-579",
          "ICD9:V47.3",
          "MEDGEN:892790",
          "MESH:D005767",
          "NANDO:1100013",
          "NCIT:C2990",
          "SCTID:53619000",
          "UMLS:C4023588",
          "icd11.foundation:1256772020"
        ],
        "synonyms": [
          "digestive disease",
          "digestive system disease",
          "digestive system disease or disorder",
          "digestive system disorder",
          "disease of digestive system",
          "disease or disorder of digestive system",
          "disorder of digestive system",
          "gastroenterological system disease",
          "gastroenterological system disorder",
          "gastrointestinal disorder",
          "gastrointestinal system disease",
          "gastrointestinal system disorder",
          "stomach or intestinal disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A disease or disorder that involves the digestive system."
      },
      "child_count": 31,
      "reference_id": "MONDO:0004335"
    },
    {
      "id": 7200,
      "label": "infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050117",
          "EFO:0005741",
          "ICD10CM:A00-B99",
          "ICD9:079.0",
          "ICD9:136.8",
          "ICD9:136.9",
          "IDO:0000436",
          "MEDGEN:1057",
          "MESH:D003141",
          "NCIT:C26726",
          "SCTID:40733004",
          "UMLS:C0009450"
        ],
        "synonyms": [
          "communicable disease",
          "infection",
          "infectious",
          "infectious disease",
          "infectious diseases and manifestations",
          "infectious disorder",
          "transmissible disease",
          "clinical infection",
          "disease by infectious agent"
        ],
        "definition": "A disorder directly resulting from the presence and activity of a microbial, viral, or parasitic agent in humans. It can be transmitted by direct or indirect contact."
      },
      "child_count": 35,
      "reference_id": "MONDO:0005550"
    }
  ],
  "children": [
    {
      "id": 2785,
      "label": "oropharyngeal anthrax",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3889,
        20028,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050059",
          "GARD:0027516"
        ],
        "synonyms": [
          "oropharynx anthrax infection"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          },
          {
            "ref": "MONDO:0024623",
            "name": "otorhinolaryngologic disease"
          }
        ],
        "definition": "A anthrax infection that involves the oropharynx."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000236"
    },
    {
      "id": 2817,
      "label": "polycystic echinococcosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6878,
        7360,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050218"
        ],
        "synonyms": [
          "human polycystic hydatid disease",
          "neotropical echinococcosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0000288"
    },
    {
      "id": 3187,
      "label": "intestinal infectious disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3168,
        4384,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:100",
          "ICD10CM:A00-A09",
          "ICD9:001-009",
          "ICD9:008.8",
          "MEDGEN:511728",
          "SCTID:266071000",
          "UMLS:C0178238"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An infectious disease involving a pathogenic inflammatory response in the intestinal mucosa."
      },
      "child_count": 6,
      "reference_id": "MONDO:0000916"
    },
    {
      "id": 3845,
      "label": "fungal esophagitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3630,
        4188,
        23208,
        23869
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13147",
          "ICD9:117.9",
          "MEDGEN:90960",
          "NCIT:C27107",
          "SCTID:235602008",
          "UMLS:C0341109"
        ],
        "synonyms": [
          "fungal esophagitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Infection of the esophagus caused by fungi, most often candida albicans and candida tropicalis. It usually affects patients with immunodeficiency disorders or diabetes mellitus. Symptoms include dysphagia and pain on swallowing."
      },
      "child_count": 4,
      "reference_id": "MONDO:0001649"
    },
    {
      "id": 4012,
      "label": "bacterial esophagitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3630,
        23208,
        23869
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13921",
          "MEDGEN:83319",
          "NCIT:C27106",
          "SCTID:235601001",
          "UMLS:C0341108"
        ],
        "synonyms": [
          "bacterial esophagitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An acute bacterial infection that affects the esophagus. Symptoms include severe pain on swallowing and retrosternal pain. Endoscopic examination reveals esophageal mucosal ulcerations and pseudomembranous formations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001832"
    },
    {
      "id": 4385,
      "label": "viral gastritis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6709,
        6834,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2327",
          "ICD9:008.8",
          "MEDGEN:107873",
          "NCIT:C27184",
          "SCTID:285344007",
          "UMLS:C0563238"
        ],
        "synonyms": [
          "Viruses caused gastritis (disease)",
          "Viruses gastritis (disease)",
          "viral gastritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Inflammation of the stomach resulting from viral infection."
      },
      "child_count": 3,
      "reference_id": "MONDO:0002270"
    },
    {
      "id": 4856,
      "label": "bacterial gastritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6709,
        6839,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4033",
          "MEDGEN:182680",
          "NCIT:C27340",
          "SCTID:723096000",
          "UMLS:C0948039"
        ],
        "synonyms": [
          "Bacteria caused gastritis (disease)",
          "Bacteria gastritis (disease)",
          "bacterial gastritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Gastritis resulting from bacteria."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002842"
    },
    {
      "id": 4857,
      "label": "fungal gastritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4188,
        6709,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4034",
          "MEDGEN:181761",
          "NCIT:C27342",
          "SCTID:723097009",
          "UMLS:C0948638"
        ],
        "synonyms": [
          "Fungi caused gastritis (disease)",
          "Fungi gastritis (disease)",
          "fungal gastritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Gastritis resulting from fungi."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002843"
    },
    {
      "id": 5713,
      "label": "viral esophagitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3630,
        6834,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:6297",
          "MEDGEN:87414",
          "NCIT:C27108",
          "SCTID:235603003",
          "UMLS:C0341110"
        ],
        "synonyms": [
          "Viruses caused esophagitis (disease)",
          "Viruses esophagitis (disease)",
          "viral esophagitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Viral infection of the esophagus. It often occurs in immunocompromised patients and it is caused by cytomegalovirus or herpes simplex virus. Symptoms include pain on swallowing, fever, and retrosternal burning."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003846"
    },
    {
      "id": 5960,
      "label": "anal verrucous carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        7659,
        21745,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:7175",
          "GARD:0023840",
          "MEDGEN:231066",
          "NCIT:C7470",
          "UMLS:C1332278"
        ],
        "synonyms": [
          "anal Buschke-Lowenstein tumor",
          "anal Buschke-Lowenstein tumour",
          "anal giant (malignant) condyloma",
          "anal verrucous carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          }
        ],
        "definition": "A large, well differentiated squamous cell carcinoma with a cauliflower-like appearance, characterized by the presence of an exophytic and endophytic growth pattern. Morphologically, there is papillomatosis and acanthosis present, however cytologically the neoplastic squamous cells have a benign appearance. Dysplastic changes are minimal. It does not respond to conservative treatment and it is regarded by many authors as an intermediate lesion between condyloma acuminatum and squamous cell carcinoma."
      },
      "child_count": 0,
      "reference_id": "MONDO:0004131"
    },
    {
      "id": 6842,
      "label": "Whipple disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6756,
        6839,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8476",
          "EFO:0000775",
          "GARD:0007889",
          "ICD10CM:K90.81",
          "ICD9:040.2",
          "MEDGEN:7347",
          "MESH:D008061",
          "MedDRA:10047931",
          "NCIT:C85228",
          "NORD:1850",
          "Orphanet:3452",
          "SCTID:41545003",
          "UMLS:C0023788",
          "icd11.foundation:1131038233"
        ],
        "synonyms": [
          "Tropheryma whipplei caused disease or disorder",
          "Tropheryma whipplei disease or disorder",
          "Tropheryma whipplei infectious disease",
          "Whipple disease",
          "intestinal lipodystrophy",
          "intestinal lipophagic granulomatosis",
          "secondary non-tropical sprue",
          "Tropheryma whippelii infection",
          "Whipple's disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A systemic infection caused by the Gram-positive bacterium Tropheryma whipplei. It affects the small intestine resulting in malabsorption. Other sites or systems affected by the infection are the joints, central nervous system, and the cardiovascular system."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005116"
    },
    {
      "id": 7319,
      "label": "campylobacteriosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2837,
        4384,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:13622",
          "EFO:0007190",
          "MEDGEN:14296",
          "MESH:D002169",
          "SCTID:86500004",
          "UMLS:C0006818",
          "icd11.foundation:1012026026"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Infections with bacteria of the genus campylobacter."
      },
      "child_count": 3,
      "reference_id": "MONDO:0005688"
    },
    {
      "id": 7388,
      "label": "gastrointestinal tuberculosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2868,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:404",
          "EFO:0007280",
          "GARD:0024230",
          "ICD9:014.80",
          "ICD9:014.81",
          "ICD9:014.86",
          "MEDGEN:52885",
          "MESH:D014385",
          "SCTID:186225008",
          "UMLS:C0041312"
        ],
        "synonyms": [
          "tuberculosis of intestines, peritoneum, and mesenteric glands"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Tuberculosis that involves any region of the gastrointestinal tract, mostly in the distal ileum and the cecum. In most cases, mycobacterium tuberculosis is the pathogen. Clinical features include abdominal pain; fever; and palpable mass in the ileocecal area."
      },
      "child_count": 10,
      "reference_id": "MONDO:0005768"
    },
    {
      "id": 7545,
      "label": "Salmonella gastroenteritis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3148,
        4384,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0007475",
          "GARD:0024259",
          "ICD9:003.0",
          "MEDGEN:48541",
          "MESH:D012478",
          "SCTID:42338000",
          "UMLS:C0036114"
        ],
        "synonyms": [
          "Salmonella caused gastroenteritis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Poisoning caused by ingestion of food harboring species of salmonella. Conditions of raising, shipping, slaughtering, and marketing of domestic animals contribute to the spread of this bacterium in the food supply."
      },
      "child_count": 0,
      "reference_id": "MONDO:0005950"
    },
    {
      "id": 7602,
      "label": "viral hepatitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4367,
        23208,
        24062
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1884",
          "EFO:0004196",
          "ICD10CM:B15-B19",
          "ICD10WHO:B15-B19",
          "ICD9:573.1",
          "MEDGEN:22652",
          "MESH:D006525",
          "NCIT:C35124",
          "SCTID:3738000",
          "UMLS:C0042721",
          "icd11.foundation:985510409"
        ],
        "synonyms": [
          "Hepatitis viral",
          "Viruses caused hepatitis",
          "Viruses hepatitis",
          "viral Hepatitis",
          "viral human hepatitis",
          "unspecified viral hepatitis with hepatic coma",
          "viral hepatitis with hepatic coma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An acute or chronic inflammation of the liver parenchyma caused by viruses. Representative examples include hepatitis A, B, and C, cytomegalovirus hepatitis, and herpes simplex hepatitis."
      },
      "child_count": 18,
      "reference_id": "MONDO:0006011"
    },
    {
      "id": 7625,
      "label": "infectious colitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6986,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000035",
          "MEDGEN:75798",
          "NCIT:C78359",
          "SCTID:39341005",
          "UMLS:C0277524"
        ],
        "synonyms": [
          "infectious colitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A viral or bacterial infectious process affecting the large intestine."
      },
      "child_count": 2,
      "reference_id": "MONDO:0006039"
    },
    {
      "id": 21309,
      "label": "parasitic intestinal disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6756,
        6859,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0009561",
          "MEDGEN:7131",
          "MESH:D007411",
          "UMLS:C0021832"
        ],
        "synonyms": [
          "intestine parasitic infection",
          "parasitic intestinal disease",
          "disease, parasitic intestinal",
          "diseases, parasitic intestinal",
          "intestinal disease, parasitic",
          "parasitic intestinal diseases"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS."
      },
      "child_count": 21,
      "reference_id": "MONDO:0024270"
    },
    {
      "id": 21335,
      "label": "internal hirudiniasis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3434,
        23208,
        23495
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:B83.4",
          "MEDGEN:578592",
          "SCTID:187227006",
          "UMLS:C0348999",
          "icd11.foundation:1840948804"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A condition resulting from accidental ingestion of leeches in drinking water. They may attach themselves to the wall of the pharynx, nasal cavity, or larynx."
      },
      "child_count": 0,
      "reference_id": "MONDO:0024302"
    },
    {
      "id": 21416,
      "label": "Aeromonas hydrophila intestinal disease",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6756,
        6843,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:008.47",
          "MEDGEN:755174",
          "SCTID:446988001",
          "UMLS:C2960005"
        ],
        "synonyms": [
          "intestinal infection caused by Aeromonas hydrophila",
          "intestinal infection due to Aeromonas hydrophila"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0024459"
    },
    {
      "id": 21566,
      "label": "colorectal Kaposi sarcoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6785,
        7430,
        21545,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025451",
          "MEDGEN:474466",
          "NCIT:C96510",
          "UMLS:C3272833"
        ],
        "synonyms": [
          "Kaposi's sarcoma (disease) of large intestine",
          "colorectal Kaposi sarcoma",
          "large intestinal Kaposi sarcoma",
          "large intestine Kaposi's sarcoma (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A Kaposi sarcoma that arises from the colon or rectum."
      },
      "child_count": 8,
      "reference_id": "MONDO:0024659"
    },
    {
      "id": 24369,
      "label": "small intestinal bacterial overgrowth",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        21546,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1708316",
          "UMLS:C3160854"
        ],
        "synonyms": [
          "SIBO"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "The presence of excessive bacteria in the small intestine that can result from result from failure of the gastric acid barrier, failure of small intestinal motility, anatomic alterations, or impairment of systemic and local immunity."
      },
      "child_count": 0,
      "reference_id": "MONDO:0400000"
    },
    {
      "id": 24447,
      "label": "liver abscess (disease)",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6878,
        6939,
        23208
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:K75.0",
          "NCIT:C99089",
          "SCTID:27916005",
          "icd11.foundation:1323593849"
        ],
        "synonyms": [
          "abscess of liver",
          "hepatic abscess"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "An abscess that involves the liver."
      },
      "child_count": 0,
      "reference_id": "MONDO:0700051"
    }
  ],
  "roots": [
    {
      "id": 6151,
      "label": "digestive system disorder"
    },
    {
      "id": 7200,
      "label": "infectious disease"
    }
  ]
}