{
  "id": 23210,
  "label": "humoral hypercalcemia of malignancy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0043455",
  "properties": {
    "xrefs": [
      "GARD:0025860",
      "MEDGEN:56210",
      "MESH:C562390",
      "NCIT:C3496",
      "SCTID:47709007",
      "UMLS:C0149911"
    ],
    "synonyms": [
      "humoral hypercalcemia of malignancy",
      "hypercalcemia of malignancy",
      "hhm",
      "mahc",
      "malignancy associated hypercalcemia",
      "malignant hypercalcemia"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Hypercalcemia generally develops as a late complication of malignancy; its appearance has grave prognostic significance. It remains unclear, however, whether death is associated with hypercalcemic crisis (uncontrolled or recurrent progressive hypercalcemia) or with advanced disease. Symptoms include central nervous system impairment such as delirium with prominent symptoms of personality change, cognitive dysfunction, disorientation, incoherent speech, and psychotic symptoms such as hallucinations and delusions, smooth muscle hypotonicity, and altered cardiovascular function."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 3771,
      "label": "hypercalcemia disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7206
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12678",
          "HP:0003072",
          "ICD10CM:E83.52",
          "ICD9:275.42",
          "MEDGEN:5686",
          "MESH:D006934",
          "NCIT:C3112",
          "SCTID:66931009",
          "UMLS:C0020437"
        ],
        "synonyms": [
          "hypercalcemia"
        ],
        "definition": "Abnormally high concentration of calcium in the peripheral blood."
      },
      "child_count": 3,
      "reference_id": "MONDO:0001566"
    },
    {
      "id": 24648,
      "label": "paraneoplastic hematological syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217,
        20314
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026398"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Paraneoplastic syndrome that involves the hematopoietic system."
      },
      "child_count": 4,
      "reference_id": "MONDO:0700253"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 3771,
      "label": "hypercalcemia disease"
    },
    {
      "id": 24648,
      "label": "paraneoplastic hematological syndrome"
    }
  ]
}