{
  "id": 23244,
  "label": "thrombocytopenic purpura",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0043768",
  "properties": {
    "xrefs": [
      "GARD:0025866",
      "MEDGEN:208992",
      "MESH:D011696",
      "NANDO:2100188",
      "NCIT:C26870",
      "SCTID:302873008",
      "UMLS:C0857305"
    ],
    "synonyms": [
      "thrombocytopenic purpura",
      "purpura, thrombopenic",
      "purpuras, thrombocytopenic",
      "purpuras, thrombopenic",
      "thrombocytopenic purpuras",
      "thrombopenic purpura",
      "thrombopenic purpuras"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "Purpura associated with a reduction in circulating blood platelets which can result from a variety of factors."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 4196,
      "label": "thrombocytopenia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4362
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1588",
          "ICD9:287.5",
          "MEDGEN:52737",
          "MESH:D013921",
          "NCIT:C3408",
          "SCTID:302215000",
          "UMLS:C0040034",
          "icd11.foundation:683583694"
        ],
        "synonyms": [
          "platelet count decreased",
          "thrombocytopenic disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A laboratory test result indicating that there is an abnormally small number of platelets in the circulating blood."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002049"
    },
    {
      "id": 4662,
      "label": "purpura",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4360
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3326",
          "HP:0000979",
          "MEDGEN:19584",
          "MESH:D011693",
          "SCTID:387778001",
          "UMLS:C0034150"
        ],
        "synonyms": [
          "purpura",
          "purpura (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A small blood vessel hemorrhage into the skin and/or mucous membranes. Newer lesions appear reddish in color. Older lesions are usually a darker purple color and eventually become a brownish-yellow color."
      },
      "child_count": 3,
      "reference_id": "MONDO:0002610"
    },
    {
      "id": 6778,
      "label": "immune system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2914",
          "EFO:0000540",
          "ICD9:279",
          "ICD9:279.1",
          "ICD9:279.10",
          "ICD9:279.19",
          "ICD9:279.4",
          "ICD9:279.49",
          "ICD9:279.8",
          "ICD9:279.9",
          "MEDGEN:5759",
          "MESH:D007154",
          "NANDO:1100004",
          "NANDO:2100202",
          "NCIT:C3507",
          "SCTID:414029004",
          "UMLS:C0021053"
        ],
        "synonyms": [
          "disease of immune system",
          "disease or disorder of immune system",
          "disorder of immune system",
          "immune disease",
          "immune disorder",
          "immune dysfunction",
          "immune system disease or disorder",
          "immune system disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A disorder resulting from an abnormality in the immune system."
      },
      "child_count": 47,
      "reference_id": "MONDO:0005046"
    },
    {
      "id": 19495,
      "label": "thrombotic microangiopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0019227",
          "ICD10CM:M31.1",
          "ICD9:446.6",
          "MEDGEN:403479",
          "MESH:D057049",
          "MedDRA:10043645",
          "NCIT:C62605",
          "Orphanet:93573",
          "SCTID:126729006",
          "UMLS:C2717961"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "The syndromes of microangiopathic hemolytic anemia, thrombocytopenia, and variable signs of organ impairment, due to platelet aggregation in the microcirculation."
      },
      "child_count": 2,
      "reference_id": "MONDO:0019737"
    }
  ],
  "children": [
    {
      "id": 9845,
      "label": "autoimmune thrombocytopenic purpura",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6463,
        18985,
        23244
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8924",
          "EFO:0007160",
          "GARD:0005194",
          "ICD10CM:D69.3",
          "ICD9:287.31",
          "MEDGEN:584986",
          "MedDRA:10021245",
          "NANDO:1200315",
          "NANDO:2200645",
          "NCIT:C3446",
          "OMIM:188030",
          "Orphanet:3002",
          "UMLS:C0398650",
          "icd11.foundation:364346400"
        ],
        "synonyms": [
          "immune thrombocytopenia",
          "ITP",
          "autoimmune thrombocytopenic purpura",
          "idiopathic thrombocytopenia",
          "idiopathic thrombocytopenia purpura",
          "idiopathic thrombocytopenic purpura",
          "thrombocytopenic purpura, autoimmune",
          "AITP",
          "immune thrombocytopenic purpura",
          "thrombocytopenic purpura autoimmune"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An autoimmune disorder in which the number of circulating platelets is reduced due to their antibody-mediated destruction. ITP is a diagnosis of exclusion and is heterogeneous in origin."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008558"
    },
    {
      "id": 18824,
      "label": "thrombotic thrombocytopenic purpura",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4413,
        23244
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10772",
          "GARD:0016659",
          "MEDGEN:48266",
          "MESH:D011697",
          "MedDRA:10043648",
          "NANDO:1200316",
          "NANDO:2100189",
          "NANDO:2200649",
          "NCIT:C78797",
          "NORD:1769",
          "Orphanet:54057",
          "SCTID:78129009",
          "UMLS:C0034155",
          "icd11.foundation:1708277768"
        ],
        "synonyms": [
          "Moschcowitz disease",
          "Moschowitz disease",
          "TTP"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Thrombotic thrombocytopenic purpura (TTP) is an aggressive and life-threatening form of thrombotic microangiopathy (TMA) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and organ failure of variable severity and is comprised of congenital TTP and acquired TTP."
      },
      "child_count": 4,
      "reference_id": "MONDO:0018896"
    }
  ],
  "roots": [
    {
      "id": 4196,
      "label": "thrombocytopenia"
    },
    {
      "id": 4662,
      "label": "purpura"
    },
    {
      "id": 6778,
      "label": "immune system disorder"
    },
    {
      "id": 19495,
      "label": "thrombotic microangiopathy"
    }
  ]
}