{
  "id": 23261,
  "label": "pneumonitis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0043905",
  "properties": {
    "xrefs": [
      "EFO:1001991",
      "MEDGEN:811420",
      "NCIT:C113159",
      "SCTID:205237003",
      "UMLS:C3714636",
      "icd11.foundation:1324545867"
    ],
    "synonyms": [
      "inflammation of lung parenchyma",
      "lung parenchyma inflammation",
      "pneumonitis"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "An inflammatory process affecting the lung parenchyma. It is a milder form of lung inflammation compared to pneumonia."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 6971,
      "label": "lung disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2809
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:850",
          "EFO:0003818",
          "ICD9:518.89",
          "MEDGEN:7399",
          "MESH:D008171",
          "NCIT:C3198",
          "SCTID:19829001",
          "UMLS:C0024115"
        ],
        "synonyms": [
          "disease of lung",
          "disease or disorder of lung",
          "disorder of lung",
          "lung disease",
          "lung disease or disorder",
          "lung disorder",
          "lung disorders",
          "pulmonary disease",
          "pulmonary diseases",
          "pulmonary disorder",
          "pulmonary disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A disease involving the lung."
      },
      "child_count": 33,
      "reference_id": "MONDO:0005275"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 4635,
      "label": "aspiration pneumonitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3240",
          "EFO:1001399",
          "MEDGEN:740734",
          "NCIT:C34932",
          "SCTID:155597006",
          "UMLS:C1761609"
        ],
        "synonyms": [
          "chemical pneumonitis",
          "aspiration pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Inflammation of the lungs due to the inhalation of solid or liquid material."
      },
      "child_count": 1,
      "reference_id": "MONDO:0002572"
    },
    {
      "id": 5401,
      "label": "toxic pneumonitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:551",
          "ICD9:506.9",
          "MEDGEN:811389",
          "SCTID:233733000",
          "UMLS:C3714582"
        ],
        "synonyms": [
          "acute chemical fume pulmonary oedema",
          "acute chemical pulmonary oedema"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A pneumonia that is an acute inflammation of the lungs induced by inhalation of metal fumes or toxic gasses and vapors. It is a sentinel health event (occupational) associated with exposure to ammonia (refrigeration, fertilizer, and oil refining industries), chlorine (alkali and bleach industries), nitrogen oxides (silo fillers, arc welders, and nitric acid industry), sulfur dioxide (paper, refrigeration, and oil refining industries), cadmium (processors and cadmium smelters), trimellitic anhydride (plastics and organic chemical synthesis), and vanadium pentoxide (boilermakers). The two types of pulmonary agents are central and peripheral. Central pulmonary agents, for example, ammonia, are water soluble irritants that injure the upper airways. Peripheral pulmonary agents, for example, phosgene, NOx, and PFIB, are slightly water soluble irritants that injure the alveolar-capillary membranes. Chlorine has both central and peripheral effects."
      },
      "child_count": 0,
      "reference_id": "MONDO:0003479"
    },
    {
      "id": 6953,
      "label": "pneumonia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        21378,
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:552",
          "EFO:0003106",
          "ICD10CM:J15",
          "ICD10CM:J18.9",
          "ICD9:483",
          "ICD9:483.8",
          "ICD9:484.8",
          "ICD9:486",
          "MEDGEN:10813",
          "MESH:D011014",
          "NCIT:C3333",
          "SCTID:233604007",
          "UMLS:C0032285",
          "icd11.foundation:142052508"
        ],
        "synonyms": [
          "acute pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, caused by an infection in one or both of the lungs (by bacteria, viruses, fungi, or mycoplasma.). Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness."
      },
      "child_count": 22,
      "reference_id": "MONDO:0005249"
    },
    {
      "id": 13155,
      "label": "ichthyosis prematurity syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4198,
        4370,
        5714,
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009886",
          "MEDGEN:324839",
          "MESH:C536271",
          "NCIT:C62590",
          "OMIM:608649",
          "Orphanet:88621",
          "SCTID:12381000132107",
          "UMLS:C1837610"
        ],
        "synonyms": [
          "IPS",
          "congenital ichthyosis type 4",
          "ichthyosis prematurity syndrome",
          "idiopathic pneumonia syndrome",
          "ichthyosis congenita 4",
          "ichthyosis congenita IV",
          "ichthyosis-prematurity syndrome"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Ichthyosis prematurity syndrome is a rare, syndromic congenital ichthyosis characterized by premature birth (at gestational weeks 30-32, in general) in addition to thick, caseous and desquamating epidermis, neonatal respiratory asphyxia, and persistent eosinophilia. After the perinatal period, a spontaneous improvement in the health of affected patients is observed and skin features (vernix caseosa-like scale) evolve into a mild presentation of flat follicular hyperkeratosis with atopy."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012089"
    },
    {
      "id": 18069,
      "label": "hypersensitivity pneumonitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3133,
        16615,
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:841",
          "GARD:0000012",
          "ICD9:495",
          "ICD9:495.8",
          "ICD9:495.9",
          "MEDGEN:1446",
          "MESH:D000542",
          "MedDRA:10001890",
          "NCIT:C34369",
          "NORD:761",
          "Orphanet:31740",
          "SCTID:37471005",
          "UMLS:C0002390"
        ],
        "synonyms": [
          "HP",
          "allergic form of pneumonitis",
          "allergic pneumonitis",
          "exogen allergic alveolitis",
          "extrinsic allergic alveolitis",
          "hypersensitivity pneumonitis",
          "allergic interstitial pneumonitis",
          "alveolitis, extrinsic allergic",
          "extrinsic allergic pneumonia hypersensitivity pneumonitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Hypersensitivity pneumonitis (HP) is a pulmonary disease with symptoms of dyspnea and cough resulting from the inhalation of an antigen to which the subject has been previously sensitized."
      },
      "child_count": 42,
      "reference_id": "MONDO:0017853"
    },
    {
      "id": 23262,
      "label": "radiation pneumonitis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16615,
        23212,
        23261
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025873",
          "MESH:D017564",
          "SCTID:84004001",
          "icd11.foundation:1914397767"
        ],
        "synonyms": [
          "radiation pneumonitis",
          "Pneumonias, radiation",
          "Pneumonitides, radiation",
          "fibrosis, radiation",
          "pneumonia, radiation",
          "pneumonitis, radiation",
          "pulmonary radiation alveolitis",
          "radiation Pneumonias",
          "radiation Pneumonitides",
          "radiation fibrosis",
          "radiation pneumonia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0043919"
    }
  ],
  "roots": [
    {
      "id": 6971,
      "label": "lung disorder"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}