{
  "id": 23269,
  "label": "central nervous system lupus",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0043985",
  "properties": {
    "xrefs": [
      "GARD:0025875",
      "MEDGEN:156265",
      "MESH:D020945",
      "NCIT:C116919",
      "UMLS:C0752332"
    ],
    "synonyms": [
      "CNS lupus",
      "central nervous system lupus",
      "Meningoencephalitides, lupus",
      "central nervous system lupus vasculitis",
      "central nervous system systemic lupus Erythematosis",
      "lupus Meningoencephalitides",
      "lupus meningoencephalitis",
      "meningoencephalitis, lupus",
      "neuropsychiatric systemic lupus erythematosus",
      "systemic lupus Erythematosis, central nervous system"
    ],
    "categories": [
      {
        "ref": "MONDO:0003900",
        "name": "connective tissue disorder"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "Inflammation that includes the brain, spinal cord and surrounding tissues secondary to systemic lupus erythematosus (SLE); it is associated with neurological and/or psychiatric features."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2996,
      "label": "autoimmune disorder of central nervous system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        4981
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060004",
          "EFO:0020092"
        ],
        "synonyms": [
          "central nervous system autoimmune disease",
          "central nervous system hypersensitivity reaction type II disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A hypersensitivity reaction type II disease that involves the central nervous system."
      },
      "child_count": 16,
      "reference_id": "MONDO:0000568"
    },
    {
      "id": 9248,
      "label": "systemic lupus erythematosus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6454,
        21247
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9074",
          "HP:0002725",
          "ICD10CM:M32",
          "ICD10WHO:M32",
          "ICD9:710.0",
          "MEDGEN:6146",
          "MESH:D008180",
          "NANDO:1200272",
          "NANDO:2200416",
          "NCIT:C3201",
          "NORD:1380",
          "OMIM:152700",
          "OMIMPS:601744",
          "Orphanet:536",
          "SCTID:55464009",
          "UMLS:C0024141",
          "icd11.foundation:749596428"
        ],
        "synonyms": [
          "Lupus",
          "SLE",
          "SLE - lupus erythematosus, systemic",
          "disseminated lupus erythematosus",
          "lupus erythematosus, systemic",
          "systemic lupus erythematosus",
          "systemic lupus erythematosus (disease)",
          "systemic lupus erythematosus susceptibility to"
        ],
        "categories": [
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific."
      },
      "child_count": 20,
      "reference_id": "MONDO:0007915"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6799
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "neurogenetic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology characterized by abnormalities in the brain, spinal cord, nerves, or muscles."
      },
      "child_count": 528,
      "reference_id": "MONDO:0100545"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2996,
      "label": "autoimmune disorder of central nervous system"
    },
    {
      "id": 9248,
      "label": "systemic lupus erythematosus"
    },
    {
      "id": 24270,
      "label": "hereditary neurological disease"
    }
  ]
}