{
  "id": 23279,
  "label": "cardio-renal syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0044079",
  "properties": {
    "xrefs": [
      "MEDGEN:453248",
      "MESH:D059347",
      "NCIT:C123225",
      "SCTID:445236007",
      "UMLS:C2242703"
    ],
    "synonyms": [
      "cardiorenal syndrome",
      "Reno Cardiac syndrome",
      "Reno-Cardiac syndrome",
      "Reno-Cardiac syndromes",
      "Renocardiac syndrome",
      "Renocardiac syndromes",
      "cardio renal syndrome",
      "cardio-renal syndromes",
      "cardiorenal syndromes",
      "syndrome, Reno-Cardiac",
      "syndrome, Renocardiac",
      "syndrome, cardio-renal",
      "syndrome, cardiorenal",
      "syndromes, Reno-Cardiac",
      "syndromes, Renocardiac",
      "syndromes, cardio-renal",
      "syndromes, cardiorenal"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A disorder of the heart and kidneys in which dysfunction of one of the organs induces dysfunction of the other organ."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 6955,
      "label": "heart failure",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0003144",
          "ICD10CM:I50",
          "ICD10WHO:I50",
          "ICD9:428",
          "ICD9:428.9",
          "MEDGEN:6749",
          "MESH:D006333",
          "NCIT:C50577",
          "SCTID:84114007",
          "UMLS:C0018801",
          "icd11.foundation:1458683894"
        ],
        "synonyms": [
          "cardiac failure",
          "cardiac insufficiency",
          "failure, heart",
          "heart failure",
          "insufficiency, Cardiac"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction."
      },
      "child_count": 4,
      "reference_id": "MONDO:0005252"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 6955,
      "label": "heart failure"
    }
  ]
}