{
  "id": 23412,
  "label": "pancreatic carcinoma with mixed differentiation",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0044727",
  "properties": {
    "xrefs": [
      "GARD:0022057",
      "MEDGEN:353935",
      "NCIT:C45843",
      "Orphanet:506112",
      "UMLS:C1709050"
    ],
    "synonyms": [
      "MiNEN of pancreas",
      "mixed exocrine-endocrine carcinoma of the pancreas",
      "pancreatic MiNEN",
      "pancreatic carcinoma with mixed differentiation",
      "pancreatic mixed neuroendocrine-nonneuroendocrine neoplasm",
      "mixed neuroendocrine-nonneuroendocrine neoplasm of pancreas"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A rare carcinoma with a poor prognosis, characterized by the presence of a mixture of exocrine and neuroendocrine malignant epithelial cells in both the pancreas and metastatic sites. Symptoms include jaundice, abdominal pain, and weight loss."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6912,
      "label": "exocrine pancreatic carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4251,
        7738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4905",
          "EFO:0002618",
          "GARD:0027717",
          "MEDGEN:65917",
          "NCIT:C3850",
          "SCTID:372142002",
          "UMLS:C0235974"
        ],
        "synonyms": [
          "cancer of pancreas",
          "cancer of the pancreas",
          "exocrine cancer",
          "pancreas cancer",
          "pancreatic cancer",
          "carcinoma of exocrine pancreas",
          "carcinoma of the pancreas",
          "exocrine pancreas carcinoma",
          "pancreas carcinoma",
          "pancreatic cancer (not islets)",
          "pancreatic carcinoma, familial"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A carcinoma that arises from epithelial cells of the exocrine pancreas"
      },
      "child_count": 16,
      "reference_id": "MONDO:0005192"
    },
    {
      "id": 7739,
      "label": "digestive system mixed adenoneuroendocrine carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000219",
          "ICDO:8244/3",
          "MEDGEN:459355",
          "NCIT:C95406",
          "UMLS:C2987129"
        ],
        "synonyms": [
          "MANEC",
          "digestive system Mixed Adenoneuroendocrine cancer",
          "digestive system mixed adenoneuroendocrine carcinoma",
          "gastrointestinal MANEC",
          "gastrointestinal mixed Adenoneuroendocrine carcinoma",
          "mixed Adenoneuroendocrine carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "A carcinoma that arises from the digestive system and is characterized by the presence of a malignant glandular epithelial component and a malignant neuroendocrine component. At least 30% of either component should be present for the diagnosis to be made."
      },
      "child_count": 1,
      "reference_id": "MONDO:0006182"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6912,
      "label": "exocrine pancreatic carcinoma"
    },
    {
      "id": 7739,
      "label": "digestive system mixed adenoneuroendocrine carcinoma"
    }
  ]
}