{
  "id": 23419,
  "label": "prekallikrein deficiency",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0044744",
  "properties": {
    "xrefs": [
      "GARD:0025905",
      "MEDGEN:75779",
      "NANDO:2200684",
      "NCIT:C99022",
      "SCTID:48976006",
      "UMLS:C0272339"
    ],
    "synonyms": [
      "prekallikrein deficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A condition characterized by the congenital or acquired deficiency of prekallikrein. This deficiency is usually not associated with bleeding. The congenital deficiency is very rare. Acquired deficiency may occur in diffuse intravascular coagulation, infections, and sickle cell disease."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 3738,
      "label": "blood coagulation disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7217
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1247",
          "EFO:0009314",
          "ICD9:286",
          "ICD9:286.9",
          "ICD9:287.8",
          "MEDGEN:604",
          "MESH:D001778",
          "NCIT:C2902",
          "SCTID:64779008",
          "UMLS:C0005779"
        ],
        "synonyms": [
          "blood coagulation disorder",
          "coagulation defect",
          "coagulation disorder",
          "coagulation disorder, blood",
          "coagulation disorders, blood",
          "coagulopathy",
          "disorder, blood coagulation",
          "disorders, blood coagulation"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A condition in which there is a deviation from or interruption of the normal coagulation properties of the blood."
      },
      "child_count": 8,
      "reference_id": "MONDO:0001531"
    }
  ],
  "children": [
    {
      "id": 13941,
      "label": "inherited prekallikrein deficiency",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4359,
        4360,
        20411,
        23419
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0004477",
          "ICD9:286.9",
          "MESH:C562725",
          "NANDO:2200684",
          "OMIM:612423",
          "Orphanet:749"
        ],
        "synonyms": [
          "congenital prekallikrein deficiency",
          "fletcher factor (prekallikrein) deficiency",
          "hereditary prekallikrein deficiency",
          "Fletcher Factor deficiency",
          "PKK deficiency",
          "prekallikrein deficiency",
          "prekallikrein deficiency, congenital"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An instance of prekallikrein deficiency that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012901"
    }
  ],
  "roots": [
    {
      "id": 3738,
      "label": "blood coagulation disease"
    }
  ]
}