{
  "id": 23434,
  "label": "nodular lymphocyte predominant Hodgkin lymphoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0044778",
  "properties": {
    "xrefs": [
      "GARD:0019079",
      "ICD10CM:C81.0",
      "MEDGEN:233758",
      "NANDO:1201067",
      "NCIT:C7258",
      "ONCOTREE:NLPHL",
      "Orphanet:86893",
      "UMLS:C1334968",
      "icd11.foundation:331115338"
    ],
    "synonyms": [
      "Hodgkin lymphoma nodular LP, NOS",
      "Hodgkin lymphoma nodular lymphocyte predominant type, NOS",
      "NLPHL",
      "nodular lymphocyte predominant Hodgkin lymphoma",
      "nodular lymphocyte predominant Hodgkin's lymphoma",
      "nodular lymphocyte-predominant Hodgkin lymphoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A monoclonal B-cell neoplasm characterized by a nodular, or a nodular and diffuse proliferation of scattered large neoplastic cells known as popcorn or lymphocyte predominant cells (LP cells)- formerly called L&H cells for lymphocytic and/or histiocytic Reed-Sternberg cell variants. The LP cells lack CD15 and CD30 in nearly all instances. Patients are predominantly male, frequently in the 30-50 year age group. Most patients present with limited stage disease (localized peripheral lymphadenopathy, stage I or II). (WHO 2008)"
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6697,
      "label": "Hodgkins lymphoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6792,
        17660
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:8567",
          "EFO:0000183",
          "GARD:0002714",
          "ICD10CM:C81",
          "ICD9:201",
          "ICD9:201.0",
          "ICD9:201.1",
          "ICD9:201.2",
          "ICD9:201.9",
          "ICD9:201.90",
          "ICDO:9650/3",
          "MESH:D006689",
          "NANDO:2200024",
          "NCIT:C9357",
          "NORD:1246",
          "ONCOTREE:HL",
          "Orphanet:98293",
          "icd11.foundation:1528863768"
        ],
        "synonyms": [
          "HL",
          "Hodgkin disease",
          "Hodgkin lymphoma",
          "Hodgkin's Disease",
          "Hodgkin's disease",
          "Hodgkin's lymphoma",
          "stage I subdiaphragmatic Hodgkin lymphoma",
          "stage II subdiaphragmatic Hodgkin lymphoma",
          "Hodgkin's sarcoma",
          "lymphoma, Hodgkin's"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A heterogeneous group of malignant lymphoid neoplasms of B-cell origin characterized histologically by the presence of Hodgkin and Reed-Sternberg (HRS) cells in the vast majority of cases. There are two distinct subtypes: nodular lymphocyte predominant Hodgkin lymphoma and classical Hodgkin lymphoma. Hodgkin lymphoma involves primarily lymph nodes."
      },
      "child_count": 10,
      "reference_id": "MONDO:0004952"
    }
  ],
  "children": [
    {
      "id": 19302,
      "label": "adult nodular lymphocyte predominant Hodgkin lymphoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        5547,
        23434
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025137",
          "MEDGEN:231044",
          "NCIT:C7942",
          "UMLS:C1332210"
        ],
        "synonyms": [
          "nodular lymphocyte predominant Hodgkin lymphoma",
          "adult NLPHD",
          "adult nodular lymphocyte predominant Hodgkin's disease",
          "adult nodular lymphocyte predominant Hodgkin's lymphoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A nodular lymphocyte predominant Hodgkin lymphoma occurring in adults."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019478"
    }
  ],
  "roots": [
    {
      "id": 6697,
      "label": "Hodgkins lymphoma"
    }
  ]
}