{
  "id": 23441,
  "label": "nasal cavity and paranasal sinus squamous cell carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0044787",
  "properties": {
    "xrefs": [
      "GARD:0025910",
      "MEDGEN:124722",
      "NCIT:C68611",
      "UMLS:C0280332"
    ],
    "synonyms": [
      "nasal cavity and paranasal sinus squamous cell cancer",
      "nasal cavity and paranasal sinus squamous cell carcinoma"
    ],
    "definition": "A rare, keratinizing or non-keratinizing squamous cell carcinoma arising from the mucosal epithelium of the nasal cavity or the paranasal sinuses. It affects most often the maxillary sinus. Less frequently, it arises from the nasal cavity, ethmoid sinus, sphenoid sinus, and frontal sinus. Symptoms include nasal fullness, epistaxis, rhinorhea, pain, and paresthesia. Patients with nasal squamous cell carcinoma usually present earlier than patients with maxillary sinus carcinoma and have a better prognosis compared to the latter group."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 11332,
      "label": "head and neck squamous cell carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4185,
        6823
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5520",
          "EFO:0000181",
          "GARD:0008503",
          "MEDGEN:257911",
          "MESH:C535575",
          "MedDRA:10060121",
          "NCIT:C34447",
          "OMIM:275355",
          "ONCOTREE:HNSC",
          "Orphanet:67037",
          "SCTID:716659002",
          "UMLS:C1168401"
        ],
        "synonyms": [
          "HNSCC",
          "SCCHN",
          "craniocervical region squamous cell carcinoma",
          "head and neck squamous cell carcinoma",
          "squamous cell carcinoma of head and neck",
          "squamous cell carcinoma of the head and neck",
          "squamous cell carcinoma, head and neck, somatic",
          "carcinoma of the head and neck",
          "squamous cell carcinoma, head and neck"
        ],
        "definition": "A squamous cell carcinoma that arises from any of the following anatomic sites: lip and oral cavity, nasal cavity, paranasal sinuses, pharynx, larynx, and salivary glands."
      },
      "child_count": 26,
      "reference_id": "MONDO:0010150"
    },
    {
      "id": 23674,
      "label": "nasal cavity and paranasal sinus carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4185,
        23675
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007650",
          "MEDGEN:328032",
          "NCIT:C54293",
          "UMLS:C1710095"
        ],
        "synonyms": [
          "nasal cavity and paranasal sinus cancer",
          "nasal cavity and paranasal sinus carcinoma",
          "paranasal sinus and nasal cavity cancer",
          "sinonasal carcinoma"
        ],
        "definition": "A carcinoma arising from the nasal cavity or paranasal sinuses."
      },
      "child_count": 4,
      "reference_id": "MONDO:0056819"
    }
  ],
  "children": [
    {
      "id": 4849,
      "label": "non-keratinizing sinonasal squamous cell carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23441
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4003",
          "GARD:0023258",
          "ICDO:8121/3",
          "MEDGEN:83119",
          "NCIT:C54287",
          "ONCOTREE:SNSC",
          "UMLS:C0334270"
        ],
        "synonyms": [
          "non-keratinizing sinonasal squamous cell carcinoma",
          "Ringertz carcinoma",
          "Schneiderian carcinoma",
          "Sinonasal Schneiderian carcinoma",
          "Sinonasal cylindrical cell carcinoma",
          "Sinonasal transitional cell carcinoma",
          "sinonasal squamous cell carcinoma"
        ],
        "definition": "A squamous cell carcinoma of the sinonasal tract characterized by a plexiform or ribbon-like growth pattern, cytological atypia, and lack of histological evidence of keratinization."
      },
      "child_count": 0,
      "reference_id": "MONDO:0002831"
    }
  ],
  "roots": [
    {
      "id": 11332,
      "label": "head and neck squamous cell carcinoma"
    },
    {
      "id": 23674,
      "label": "nasal cavity and paranasal sinus carcinoma"
    }
  ]
}