{
  "id": 23444,
  "label": "combined hepatocellular carcinoma and cholangiocarcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0044791",
  "properties": {
    "xrefs": [
      "GARD:0022200",
      "MEDGEN:113160",
      "NCIT:C3828",
      "Orphanet:529852",
      "SCTID:274902006",
      "UMLS:C0221287",
      "icd11.foundation:1097637010",
      "icd11.foundation:1600108866",
      "icd11.foundation:894488488"
    ],
    "synonyms": [
      "carcinoma of liver and intrahepatic biliary tract",
      "liver and intrahepatic biliary tract carcinoma",
      "Cholangiohepatoma",
      "Hepatocholangiocarcinoma",
      "Mixed hepatocellular cholangiocarcinoma",
      "carcinoma of the liver and intrahepatic biliary tract",
      "combined hepatocellular cancer and cholangiocarcinoma (bile duct cancer)",
      "combined hepatocellular cancer and intrahepatic bile duct cancer (cholangiocarcinoma)",
      "combined hepatocellular carcinoma and cholangiocarcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A rare tumor containing unequivocal elements of both hepatocellular and cholangiocarcinoma that are intimately admixed. This tumor should be distinguished from separate hepatocellular carcinoma and cholangiocarcinoma arising in the same liver. The prognosis of this tumor is poor."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18555,
      "label": "adenocarcinoma of gallbladder and extrahepatic biliary tract",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4714,
        18842
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021791",
          "MEDGEN:1633887",
          "Orphanet:424991",
          "SCTID:765741003",
          "UMLS:C4707555"
        ],
        "synonyms": [
          "adenocarcinoma of gallbladder and EBT",
          "adenocarcinoma of the gallbladder and EBT",
          "adenocarcinoma of the gallbladder and extrahepatic biliary tract"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Adenocarcinoma of the gallbladder and extrahepatic biliary tract is a rare epithelial carcinoma, arising either in the gallbladder itself or from the epithelium lining the extrahepatic biliary tree, cystic duct and/or peribiliary gland, characterized by nonspecific symptoms, such as abdominal pain, jaundice and vomiting and sometimes mimicking benign biliary diseases. Chronic biliary epithelial inflammation (e.g. primary sclerosing cholangitis, cholelithiasis, choledocholithiasis, liver fluke infestation) is a major risk factor."
      },
      "child_count": 4,
      "reference_id": "MONDO:0018536"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18555,
      "label": "adenocarcinoma of gallbladder and extrahepatic biliary tract"
    }
  ]
}