{
  "id": 23497,
  "label": "sympathetic nervous system disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0044993",
  "properties": {
    "xrefs": [
      "MEDGEN:148206",
      "SCTID:50330009",
      "UMLS:C0750946"
    ],
    "synonyms": [
      "disease of sympathetic nervous system",
      "disease or disorder of sympathetic nervous system",
      "disorder of sympathetic nervous system",
      "sympathetic nervous system disease",
      "sympathetic nervous system disease or disorder"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A disease or disorder that involves the sympathetic nervous system."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 3525,
      "label": "autonomic nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4657,
        5512
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11465",
          "EFO:0009532",
          "ICD9:337.1",
          "ICD9:337.9",
          "MEDGEN:218837",
          "MESH:D001342",
          "SCTID:128123007",
          "SCTID:15241006",
          "UMLS:C1145628",
          "icd11.foundation:1397803237"
        ],
        "synonyms": [
          "autonomic nervous disease",
          "autonomic nervous system disease",
          "autonomic nervous system disease or disorder",
          "disease of autonomic nervous system",
          "disease or disorder of autonomic nervous system",
          "disorder of autonomic nervous system",
          "disorder of peripheral autonomic nervous system",
          "disorder of the autonomic nervous system",
          "autonomic peripheral nervous system diseases",
          "dysautonomia",
          "peripheral autonomic nervous system diseases",
          "ANS (autonomic nervous system) diseases",
          "ANS disease",
          "ANS diseases",
          "autonomic central nervous system diseases",
          "autonomic disease",
          "autonomic diseases",
          "autonomic dysfunction, segmental",
          "autonomic dysfunctions, segmental",
          "autonomic nervous system disorders",
          "central autonomic nervous system diseases",
          "disorders of the autonomic nervous system",
          "nervous system diseases, autonomic",
          "nervous system diseases, sympathetic",
          "segmental autonomic dysfunction",
          "segmental autonomic dysfunctions"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disease involving the autonomic nervous system."
      },
      "child_count": 26,
      "reference_id": "MONDO:0001292"
    }
  ],
  "children": [
    {
      "id": 6767,
      "label": "ganglioneuroma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3043,
        4464,
        7851,
        17182,
        20329,
        23497
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4817",
          "EFO:0000500",
          "GARD:0020731",
          "HP:0003005",
          "ICD9:215.9",
          "ICDO:9490/0",
          "MEDGEN:6545",
          "MedDRA:10017709",
          "NCIT:C3049",
          "ONCOTREE:GN",
          "Orphanet:251992",
          "SCTID:116371000119107",
          "UMLS:C0017075",
          "birnlex:12617"
        ],
        "synonyms": [
          "ganglioneuroma",
          "ganglioneuroma (Schwannian Stroma-dominant)",
          "ganglioneuroma (disease)",
          "ganglioneuroma, benign",
          "neural Crest tumor, benign",
          "GN"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A benign neuroblastic tumor of the sympathetic nervous system that occurs in childhood. Ganglioneuroma typically arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. Common presenting features include a palpable abdominal mass, hepatomegaly, and a thoracic mass detected on routine chest X-ray."
      },
      "child_count": 6,
      "reference_id": "MONDO:0005033"
    },
    {
      "id": 20313,
      "label": "sympathetic paraganglioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2912,
        7265,
        23497
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025286",
          "ICDO:8681/1",
          "MEDGEN:137758",
          "MESH:C531777",
          "NCIT:C4216",
          "SCTID:399343007",
          "UMLS:C0334415"
        ],
        "synonyms": [
          "Chromaffinoma",
          "chromaffin neoplasm",
          "chromaffin tumor",
          "chromaffin tumour",
          "paraganglioma of sympathetic nervous system",
          "sympathetic Paraganglionic neoplasm",
          "sympathetic nervous system paraganglioma",
          "sympathetic paraganglioma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A benign or malignant paraganglioma arising from the chromaffin cells of the paraganglia that are located along the sympathetic nerves. It includes extra-adrenal paragangliomas and paragangliomas that arise from the adrenal medulla. The latter are commonly referred to as pheochromocytomas. Representative examples of extra-adrenal sympathetic paragangliomas include the bladder, and superior and inferior paraaortic paragangliomas. Clinical signs are related to the secretion of catecholamines resulting in hypertension."
      },
      "child_count": 6,
      "reference_id": "MONDO:0021072"
    }
  ],
  "roots": [
    {
      "id": 3525,
      "label": "autonomic nervous system disorder"
    }
  ]
}