{
  "id": 23547,
  "label": "major salivary gland adenoid cystic carcinoma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0045063",
  "properties": {
    "xrefs": [
      "GARD:0025941",
      "MEDGEN:235286",
      "NCIT:C5905",
      "UMLS:C1334548"
    ],
    "synonyms": [
      "adenoid cystic carcinoma of major salivary gland",
      "adenoid cystic carcinoma of the major salivary gland",
      "major salivary gland adenoid cystic cancer",
      "major salivary gland adenoid cystic carcinoma"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0006858",
        "name": "mouth disorder"
      }
    ],
    "definition": "An aggressive carcinoma that arises from the major salivary glands. It is characterized by the presence of malignant epithelial and myoepithelial cells forming cribriform, tubular, and solid patterns. It usually presents as a slow growing mass. Patients develop pain because of the tendency of these carcinomas to invade perineural tissues."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 5139,
      "label": "salivary gland adenoid cystic carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2972,
        6713
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:4866",
          "GARD:0023398",
          "MEDGEN:79034",
          "NCIT:C8026",
          "SCTID:422833009",
          "UMLS:C0279751"
        ],
        "synonyms": [
          "adenoid cystic cancer",
          "adenoid cystic carcinoma (morphologic abnormality)",
          "adenoid cystic carcinoma of salivary gland",
          "adenoid cystic carcinoma of the salivary gland",
          "cylindroma (morphologic abnormality)",
          "saliva-secreting gland adenoid cystic carcinoma",
          "salivary gland adenoid cystic cancer",
          "salivary gland adenoid cystic carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "An adenoid cystic carcinoma arising from the salivary gland. It is characterized by the presence of epithelial and myoepithelial cells forming tubular, cribriform, and solid patterns. It usually presents as a slow growing mass. Patients may experience pain because of the tumor propensity for perineural invasion. The tumor may follow an aggressive clinical course with recurrences and mestastases to distant sites including lungs, bones, brain, and liver."
      },
      "child_count": 4,
      "reference_id": "MONDO:0003175"
    },
    {
      "id": 7827,
      "label": "major salivary gland carcinoma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2972,
        23418
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000344",
          "GARD:0027745",
          "MEDGEN:235287",
          "NCIT:C5907",
          "UMLS:C1334549"
        ],
        "synonyms": [
          "major salivary gland cancer",
          "carcinoma of Major salivary gland",
          "carcinoma of major salivary gland",
          "carcinoma of the major salivary gland",
          "major salivary gland carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A carcinoma that arises from the parotid gland, submandibular gland, or sublingual gland."
      },
      "child_count": 12,
      "reference_id": "MONDO:0006284"
    }
  ],
  "children": [
    {
      "id": 2986,
      "label": "sublingual gland adenoid cystic carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20311,
        23547
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050930",
          "GARD:0022798"
        ],
        "synonyms": [
          "sublingual gland adenoid cystic carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "A adenoid cystic carcinoma that involves the sublingual gland."
      },
      "child_count": 0,
      "reference_id": "MONDO:0000545"
    },
    {
      "id": 7882,
      "label": "parotid gland adenoid cystic carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        20508,
        23547
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050931",
          "EFO:1000459",
          "GARD:0024381",
          "MEDGEN:277502",
          "NCIT:C5937",
          "SCTID:423615009",
          "UMLS:C1335355"
        ],
        "synonyms": [
          "adenoid cystic carcinoma of parotid",
          "adenoid cystic carcinoma of parotid gland",
          "adenoid cystic carcinoma of the parotid",
          "adenoid cystic carcinoma of the parotid gland",
          "parotid adenoid cystic carcinoma",
          "parotid gland adenoid cystic carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "An aggressive carcinoma that arises from the parotid gland. It is characterized by the presence of malignant epithelial and myoepithelial cells forming cribriform, tubular, and solid patterns. It usually presents as a slow growing mass. Patients develop pain because of the tendency of these carcinomas to invade perineural tissues."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006356"
    },
    {
      "id": 7949,
      "label": "submandibular gland adenoid cystic carcinoma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        6500,
        23547
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000555",
          "GARD:0024412",
          "MEDGEN:277773",
          "NCIT:C5935",
          "SCTID:423189008",
          "UMLS:C1336522"
        ],
        "synonyms": [
          "adenoid cystic carcinoma of submandibular gland",
          "adenoid cystic carcinoma of the submandibular gland",
          "submandibular gland adenoid cystic carcinoma"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0006858",
            "name": "mouth disorder"
          }
        ],
        "definition": "An aggressive carcinoma that arises from the submandibular gland. It is characterized by the presence of malignant epithelial and myoepithelial cells forming cribriform, tubular, and solid patterns. It usually presents as a slow growing mass. Patients develop pain because of the tendency of these carcinomas to invade perineural tissues."
      },
      "child_count": 0,
      "reference_id": "MONDO:0006436"
    }
  ],
  "roots": [
    {
      "id": 5139,
      "label": "salivary gland adenoid cystic carcinoma"
    },
    {
      "id": 7827,
      "label": "major salivary gland carcinoma"
    }
  ]
}