{
  "id": 23767,
  "label": "structural congenital heart disease, multiple types - GATA4",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100009",
  "properties": {
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Any congenital heart disease in which the cause of the disease is a mutation in the GATA4 gene."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 7116,
      "label": "congenital heart disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6967,
        21294
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1682",
          "EFO:0005207",
          "ICD9:746.84",
          "ICD9:746.89",
          "ICD9:746.9",
          "MEDGEN:57501",
          "MESH:D006330",
          "NCIT:C95834",
          "SCTID:13213009",
          "UMLS:C0152021",
          "icd11.foundation:2004408087"
        ],
        "synonyms": [
          "heart malformation",
          "congenital anomaly of heart",
          "congenital heart defect",
          "congenital heart defects",
          "Abnormality, heart",
          "abnormalities, heart",
          "defect, congenital heart",
          "defects, congenital heart",
          "heart abnormalities",
          "heart abnormality",
          "heart defect, congenital",
          "heart, malformation Of"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A heart disease that is present at birth. Representative examples include atrial septal defect, ventricular septal defect, tetralogy of Fallot, and patent foramen ovale."
      },
      "child_count": 46,
      "reference_id": "MONDO:0005453"
    },
    {
      "id": 24272,
      "label": "cardiogenetic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6967
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "hereditary heart disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions, with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology that are characterized by abnormalities in the cardiovascular system."
      },
      "child_count": 146,
      "reference_id": "MONDO:0100547"
    }
  ],
  "children": [
    {
      "id": 13012,
      "label": "atrial septal defect 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        8134,
        23767
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110107",
          "GARD:0024832",
          "MEDGEN:334249",
          "MESH:C538263",
          "OMIM:607941",
          "UMLS:C1842778"
        ],
        "synonyms": [
          "ASD2",
          "GATA4 atrial heart septal defect",
          "atrial heart septal defect caused by mutation in GATA4",
          "atrial heart septal defect type 2",
          "atrial septal defect 2",
          "atrial septal defect type 2"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any atrial heart septal defect in which the cause of the disease is a mutation in the GATA4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011938"
    },
    {
      "id": 14764,
      "label": "ventricular septal defect 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4213,
        23767
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:482407",
          "OMIM:614429",
          "UMLS:C3280777"
        ],
        "synonyms": [
          "GATA4 ventricular septal defect (disease)",
          "ventricular septal defect (disease) caused by mutation in GATA4",
          "ventricular septal defect 1",
          "ventricular septal defect type 1",
          "VSD1"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any ventricular septal defect in which the cause of the disease is a mutation in the GATA4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013746"
    },
    {
      "id": 14765,
      "label": "atrioventricular septal defect 4",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19775,
        23767
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024944",
          "MEDGEN:482411",
          "OMIM:614430",
          "UMLS:C3280781"
        ],
        "synonyms": [
          "GATA4 atrioventricular septal defect",
          "atrioventricular septal defect 4",
          "atrioventricular septal defect caused by mutation in GATA4",
          "atrioventricular septal defect type 4",
          "AVSD4"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any atrioventricular septal defect in which the cause of the disease is a mutation in the GATA4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013747"
    }
  ],
  "roots": [
    {
      "id": 7116,
      "label": "congenital heart disease"
    },
    {
      "id": 24272,
      "label": "cardiogenetic disease"
    }
  ]
}