{
  "id": 23775,
  "label": "pityriasis rubra pilaris",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100017",
  "properties": {
    "xrefs": [
      "DOID:9212",
      "GARD:0007401",
      "ICD10CM:L44.0",
      "ICD9:696.4",
      "MEDGEN:45939",
      "MESH:D010916",
      "NCIT:C85014",
      "NORD:1582",
      "SCTID:3755001",
      "UMLS:C0032027",
      "icd11.foundation:2048594962"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ],
    "definition": "A group of skin conditions that cause constant inflammation and scaling of the skin. People with PRP have reddish, scaly patches that may occur everywhere on the body, or only on certain areas. Some people with PRP also develop thickened skin on the underside of the hands and feet (palmoplantar keratoderma), various nail abnormalities, and/or thinning of the hair. There are several types of PRP classified by age when symptoms begin, body areas involved, and whether other conditions are present. This condition occurs in adults (adult onset PRP) as well as children (juvenile onset PRP)."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 3,
  "parents": [
    {
      "id": 19131,
      "label": "erythrokeratoderma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19129
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0018986",
          "ICD9:757.39",
          "MEDGEN:609461",
          "MedDRA:10015280",
          "Orphanet:79355",
          "SCTID:254215005",
          "UMLS:C0432330"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "An umbrella term for a group of rare genetic skin disorders characterized by well-demarcated plaques of reddened, dry and thickened skin. Typically, these lesions are distributed symmetrically on the body and tend to slowly expand and progress over time."
      },
      "child_count": 6,
      "reference_id": "MONDO:0019270"
    }
  ],
  "children": [
    {
      "id": 9558,
      "label": "familial pityriasis rubra pilaris",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23775,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024612",
          "MEDGEN:443914",
          "MESH:C531784",
          "MedDRA:10035116",
          "OMIM:173200",
          "Orphanet:2897",
          "UMLS:C2930842"
        ],
        "synonyms": [
          "pityriasis rubra pilaris",
          "Devergie's disease",
          "PRP",
          "hereditary pityriasis rubra pilaris",
          "pityriasis rubra pilaris--familial type"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A rare chronic papulosquamous disorder of unknown etiology characterized by small follicular papules, scaly red-orange patches, and palmoplantar hyperkeratosis, which may progress to plaques or erythroderma. Although most of the cases are sporadic and acquired, a familial form of the disease exists."
      },
      "child_count": 0,
      "reference_id": "MONDO:0008251"
    },
    {
      "id": 23776,
      "label": "adult onset pityriasis rubra pilaris",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23775
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026015"
        ],
        "synonyms": [
          "adult onset PRP"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A pityriasis rubra pilaris that occurs around the fifth or sixth decade of life."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100018"
    },
    {
      "id": 23790,
      "label": "juvenile onset pityriasis rubra pilaris",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23775
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026020"
        ],
        "synonyms": [
          "juvenile onset PRP"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "A pityriasis rubra pilaris that has a juvenile onset. The peak incidence has a bimodal distribution, with the first peak at age six to seven yearss. The classical childhood-onset subtype of PRP usually develops in the late teenage years but may also be seen in the first few years of life."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100037"
    }
  ],
  "roots": [
    {
      "id": 19131,
      "label": "erythrokeratoderma"
    }
  ]
}