{
  "id": 23783,
  "label": "epilepsy of infancy with migrating focal seizures",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100025",
  "properties": {
    "xrefs": [
      "GARD:0026016",
      "MEDGEN:1381392",
      "NANDO:1200595",
      "SCTID:733195008",
      "UMLS:C4518639",
      "icd11.foundation:1727727812"
    ],
    "synonyms": [
      "EIMFS"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "This syndrome is characterized by onset of refractory focal seizures in the first year of life, with associated severe encephalopathy. Focal seizures arise independently in both hemispheres and can migrate from one cortical region to another randomly but consecutively in the same seizure. Seizures are often prolonged with episodes of status epilepticus. Prognosis is poor with severe neurological disability and reduced life expectancy, although a milder evolution has been reported in a few children."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 25074,
      "label": "neonatal/infantile-onset epilepsy syndrome with developmental and epileptic encephalopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23780
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0027298"
        ],
        "synonyms": [
          "NIE-SDE"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A neonatal/infantile epilepsy syndrome characterized by the onset of non-self-limiting seizures and developmental regression or delay in infants/neonates. This condition is typically caused by genetic mutations that disrupt normal brain development, affecting both cognitive and motor development that is not responsive to typical seizure treatments."
      },
      "child_count": 4,
      "reference_id": "MONDO:0800490"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 25074,
      "label": "neonatal/infantile-onset epilepsy syndrome with developmental and epileptic encephalopathy"
    }
  ]
}