{
  "id": 23822,
  "label": "neuroendocrine disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100070",
  "properties": {
    "xrefs": [
      "MEDGEN:1843486",
      "UMLS:C0541403"
    ],
    "synonyms": [
      "neuroendocrine system disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A disease or disorder that affects the neuroendocrine gland, any of the organized aggregations of cells that function as secretory or excretory organs and that release hormones in response to neural stimuli."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 6799,
      "label": "nervous system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:863",
          "EFO:0000618",
          "ICD10CM:G00-G99",
          "ICD9:349.89",
          "ICD9:349.9",
          "MEDGEN:14336",
          "MESH:D009422",
          "NCIT:C26835",
          "SCTID:118940003",
          "UMLS:C0027765",
          "Wikipedia:Nervous_system_disease"
        ],
        "synonyms": [
          "disease of nervous system",
          "disease or disorder of nervous system",
          "disorder of nervous system",
          "nervous system disease",
          "nervous system disease or disorder",
          "nervous system disorder",
          "neurologic disease",
          "neurologic disorder",
          "neurological disease",
          "neurological disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the brain, spinal cord, or peripheral nerves."
      },
      "child_count": 72,
      "reference_id": "MONDO:0005071"
    },
    {
      "id": 6875,
      "label": "endocrine system disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:28",
          "EFO:0001379",
          "ICD9:259.8",
          "ICD9:259.9",
          "MEDGEN:4043",
          "MESH:D004700",
          "NANDO:1100009",
          "NANDO:2100109",
          "NCIT:C3009",
          "SCTID:362969004",
          "UMLS:C0014130"
        ],
        "synonyms": [
          "disease of endocrine system",
          "disease or disorder of endocrine system",
          "disorder of endocrine system",
          "endocrine disease",
          "endocrine disorder",
          "endocrine system disease",
          "endocrine system disease or disorder",
          "endocrine system disorder",
          "endocrinopathy",
          "thyroid or other glandular disorders"
        ],
        "categories": [
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A disease involving the endocrine system."
      },
      "child_count": 48,
      "reference_id": "MONDO:0005151"
    }
  ],
  "children": [
    {
      "id": 5202,
      "label": "posterior pituitary gland neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17888,
        23822
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:5048",
          "GARD:0023428",
          "MEDGEN:235368",
          "NCIT:C7157",
          "UMLS:C1334957"
        ],
        "synonyms": [
          "Neurohypophysis neoplasm",
          "Neurohypophysis tumor",
          "Neurohypophysis tumour",
          "PITUICYTOMA, benign",
          "neoplasm of neurohypophysis",
          "neurohypophysis neoplasm",
          "neurohypophysis neoplasm (disease)",
          "neurohypophysis tumor",
          "neurohypophysis tumour",
          "posterior pituitary gland neoplasm",
          "posterior pituitary gland tumor",
          "posterior pituitary gland tumour",
          "posterior pituitary neoplasm",
          "posterior pituitary tumor",
          "posterior pituitary tumour",
          "tumor of neurohypophysis",
          "tumour of neurohypophysis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0003900",
            "name": "connective tissue disorder"
          },
          {
            "ref": "MONDO:0005039",
            "name": "reproductive system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A low-grade neoplasm that arises from the neurohypophysis. It includes the granular cell tumor of the neurohypophysis and pituicytoma."
      },
      "child_count": 8,
      "reference_id": "MONDO:0003257"
    },
    {
      "id": 11916,
      "label": "cyclic vomiting syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23822
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:57509",
          "NANDO:2100258",
          "NANDO:2200919",
          "OMIM:500007",
          "UMLS:C0152164",
          "icd11.foundation:1434288855"
        ],
        "synonyms": [
          "cyclic vomiting syndrome",
          "CVS",
          "Cvs-plus",
          "cyclic vomiting syndrome with neuromuscular disease",
          "cyclic vomiting syndrome-plus"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A rare functional disorder characterized by recurrent, stereotypical episodes of severe nausea and vomiting separated by symptom-free intervals. Episodes are often accompanied by pallor, lethargy, and abdominal pain. The condition shows a strong association with migraine headaches and may have maternal inheritance patterns suggestive of mitochondrial involvement."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010778"
    },
    {
      "id": 16543,
      "label": "central diabetes insipidus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16072,
        23822
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081055",
          "GARD:0006015",
          "HP:0000863",
          "MEDGEN:146919",
          "MedDRA:10068587",
          "NANDO:1200375",
          "NANDO:2200324",
          "Orphanet:178029",
          "UMLS:C0687720",
          "icd11.foundation:1009553897"
        ],
        "synonyms": [
          "CDI",
          "neurogenic diabetes insipidus",
          "diabetes insipidus cranial type",
          "diabetes insipidus neurogenic",
          "diabetes insipidus neurohypophyseal"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "Central diabetes insipidus (CDI) is a hypothalamus-pituitary disease characterized by polyuria and polydipsia due to a vasopressin (AVP) deficiency. It can be inherited or acquired (hereditary CDI and acquired CDI)."
      },
      "child_count": 4,
      "reference_id": "MONDO:0015790"
    },
    {
      "id": 20442,
      "label": "pineal body neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4223,
        5067,
        20429,
        23822
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:237252",
          "NCIT:C3328",
          "ONCOTREE:PINT",
          "UMLS:C1412004"
        ],
        "synonyms": [
          "neoplasm of pineal area",
          "neoplasm of pineal body",
          "neoplasm of pineal region",
          "neoplasm of the pineal area",
          "neoplasm of the pineal region",
          "pineal area neoplasm",
          "pineal area tumor",
          "pineal area tumour",
          "pineal body neoplasm (disease)",
          "pineal body tumor",
          "pineal body tumour",
          "pineal neoplasm",
          "pineal region neoplasm",
          "pineal region tumor",
          "pineal region tumour",
          "pineal tumor",
          "pineal tumour",
          "pinealoma",
          "tumor of pineal area",
          "tumor of pineal body",
          "tumor of pineal region",
          "tumor of the pineal area",
          "tumor of the pineal region",
          "tumour of pineal area",
          "tumour of pineal body",
          "tumour of pineal region",
          "tumour of the pineal area",
          "tumour of the pineal region"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A neoplasm (disease) that involves the pineal body."
      },
      "child_count": 20,
      "reference_id": "MONDO:0021232"
    }
  ],
  "roots": [
    {
      "id": 6799,
      "label": "nervous system disorder"
    },
    {
      "id": 6875,
      "label": "endocrine system disorder"
    }
  ]
}