{
  "id": 23856,
  "label": "brain small vessel disease 3",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100105",
  "properties": {
    "xrefs": [
      "DOID:0112315",
      "GARD:0026049",
      "MEDGEN:1677948",
      "OMIM:618360",
      "UMLS:C5193053"
    ],
    "synonyms": [
      "BSVD3"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An autosomal recessive disorder resulting from fragility of cerebral vessels causing an increased risk of intracranial bleeding. The resultant phenotype is highly variable depending on timing and location of the intracranial bleed. Some patients may have onset in utero or early infancy, with subsequent global developmental delay, spasticity, and porencephaly on brain imaging. Other patients may have normal or mildly delayed development with sudden onset of intracranial hemorrhage causing acute neurologic deterioration."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 19950,
      "label": "familial porencephaly",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        12183,
        17717,
        24270
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0112313",
          "GARD:0002258",
          "MEDGEN:401353",
          "OMIMPS:175780",
          "Orphanet:99810",
          "UMLS:C1867983",
          "icd11.foundation:1833583032"
        ],
        "synonyms": [
          "hereditary porencephaly",
          "familial porencephalic white matter disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An instance of porencephaly that is caused by an inherited modification of the individual's genome."
      },
      "child_count": 21,
      "reference_id": "MONDO:0020496"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 19950,
      "label": "familial porencephaly"
    }
  ]
}