{
  "id": 23974,
  "label": "paroxysmal familial ventricular fibrillation",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100234",
  "properties": {
    "xrefs": [
      "GARD:0004227",
      "MEDGEN:83310",
      "Orphanet:228140",
      "UMLS:C0340493"
    ],
    "synonyms": [
      "IVF",
      "idiopathic ventricular fibrillation",
      "idiopathic ventricular fibrillation, non Brugada type",
      "paroxysmal familial ventricular fibrillation",
      "paroxysmal familial ventricular fibrillation (disorder)",
      "paroxysmal ventricular fibrillation",
      "ventricular fibrillation, paroxysmal familial"
    ],
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A rare, genetic, cardiac rhythm disease characterized by ventricular fibrillation in the absence of any structural or functional heart disease, or known repolarization abnormalities. The presence of J waves is associated with a higher risk of nocturnal ventricular fibrillation events and a higher risk of recurrence."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 2763,
      "label": "ventricular fibrillation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8666
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0004287",
          "HP:0001663",
          "ICD10CM:I49.01",
          "ICD9:427.41",
          "MEDGEN:21844",
          "MESH:D014693",
          "NANDO:2100052",
          "NANDO:2200227",
          "NCIT:C50799",
          "SCTID:71908006",
          "UMLS:C0042510",
          "icd11.foundation:1662472992"
        ],
        "synonyms": [
          "VF",
          "VFib",
          "fibrillation, ventricular",
          "ventricular fibrillation",
          "ventricular fibrillation (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A disorder characterized by an electrocardiographic finding of a rapid grossly irregular ventricular rhythm with marked variability in QRS cycle length, morphology, and amplitude. The rate is typically greater than 300 bpm. (CDISC)"
      },
      "child_count": 1,
      "reference_id": "MONDO:0000190"
    },
    {
      "id": 26601,
      "label": "cardiogenetic rhythm disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        8666,
        24272
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "cardiogenetic rhythm disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any cardiac rhythm disorder with a monogenic etiology that includes, but is not limited to, atrial fibrillation, sick sinus syndrome, progressive cardiac conduction disease, ventricular fibrillation, Brugada syndrome, long QT syndrome, short QT syndrome, tachycardia with fibrillation."
      },
      "child_count": 18,
      "reference_id": "MONDO:1010180"
    }
  ],
  "children": [
    {
      "id": 12486,
      "label": "ventricular fibrillation, paroxysmal familial, type 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23974,
        26602
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024795",
          "MEDGEN:414502",
          "MESH:C567851",
          "OMIM:603829",
          "SCTID:233915000",
          "UMLS:C2751898"
        ],
        "synonyms": [
          "VF1",
          "ventricular fibrillation, familial, 1",
          "ventricular fibrillation, paroxysmal familial, 1",
          "ventricular fibrillation, paroxysmal familial, type 1",
          "IVF",
          "ventricular fibrillation during myocardial infarction, susceptibility to"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0011376"
    },
    {
      "id": 14101,
      "label": "ventricular fibrillation, paroxysmal familial, 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23974
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015596",
          "MEDGEN:442823",
          "MESH:C567841",
          "OMIM:612956",
          "UMLS:C2751829"
        ],
        "synonyms": [
          "DPP6 ventricular fibrillation (disease)",
          "ventricular fibrillation (disease) caused by mutation in DPP6",
          "ventricular fibrillation, paroxysmal familial, 2",
          "ventricular fibrillation, paroxysmal familial, type 2",
          "VF2"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any ventricular fibrillation in which the cause of the disease is a mutation in the DPP6 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013063"
    }
  ],
  "roots": [
    {
      "id": 2763,
      "label": "ventricular fibrillation"
    },
    {
      "id": 26601,
      "label": "cardiogenetic rhythm disorder"
    }
  ]
}