{
  "id": 23979,
  "label": "inherited hypertrophic pyloric stenosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100239",
  "properties": {
    "xrefs": [
      "MEDGEN:196010",
      "OMIMPS:179010",
      "UMLS:C0700639"
    ],
    "synonyms": [
      "hereditary hypertrophic pyloric stenosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      }
    ],
    "definition": "An instance of hypertrophic pyloric stenosis that is inherited."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 6,
  "parents": [
    {
      "id": 3765,
      "label": "hypertrophic pyloric stenosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3766,
        6756
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12638",
          "EFO:0004707",
          "ICD10CM:Q40.0",
          "ICD9:750.5",
          "MESH:D046248",
          "NCIT:C98952",
          "SCTID:48644003"
        ],
        "synonyms": [
          "IHPS",
          "congenital Hypertrophy of the pylorus",
          "congenital constriction of the pylorus",
          "congenital hypertrophic pyloric stenosis",
          "congenital pyloric stenosis",
          "congenital stricture of the pylorus",
          "infantile Hypertrophy of the pylorus",
          "infantile constriction of the pylorus",
          "infantile hypertrophic pyloric stenosis",
          "infantile pyloric stenosis",
          "infantile stricture of the pylorus",
          "pyloric stenosis, infantile"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ],
        "definition": "An abnormality characterized by thickening of the muscle in the wall of the pylorus. It results in the narrowing of the pyloric channel. The overlying mucosa may appear hypertrophic as well. Clinical signs and symptoms appear early in life and include projectile vomiting and dehydration."
      },
      "child_count": 4,
      "reference_id": "MONDO:0001560"
    },
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    }
  ],
  "children": [
    {
      "id": 9656,
      "label": "pyloric stenosis, infantile hypertrophic, 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23979
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:357978",
          "OMIM:179010",
          "UMLS:C1867403"
        ],
        "synonyms": [
          "IHPS1",
          "pyloric stenosis, infantile hypertrophic 1, multifactorial",
          "pyloric stenosis, infantile hypertrophic, 1",
          "pyloric stenosis, infantile",
          "pyloric stenosis, infantile hypertrophic"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0008355"
    },
    {
      "id": 11572,
      "label": "pyloric stenosis, infantile hypertrophic, 4",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23979
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:395521",
          "MESH:C567472",
          "OMIM:300711",
          "UMLS:C2678037"
        ],
        "synonyms": [
          "IHPS4",
          "pyloric stenosis, infantile hypertrophic, 4"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0010411"
    },
    {
      "id": 13507,
      "label": "pyloric stenosis, infantile hypertrophic, 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23979
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:339934",
          "MESH:C565208",
          "OMIM:610260",
          "UMLS:C1853228"
        ],
        "synonyms": [
          "IHPS2",
          "pyloric stenosis, infantile hypertrophic, 2"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0012457"
    },
    {
      "id": 13825,
      "label": "pyloric stenosis, infantile hypertrophic, 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23979
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:383144",
          "MESH:C567435",
          "OMIM:612017",
          "UMLS:C2677588"
        ],
        "synonyms": [
          "IHPS3",
          "pyloric stenosis, infantile hypertrophic, 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0012785"
    },
    {
      "id": 13962,
      "label": "pyloric stenosis, infantile hypertrophic, 5",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23979
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:390899",
          "MESH:C567283",
          "OMIM:612525",
          "UMLS:C2675862"
        ],
        "synonyms": [
          "IHPS5",
          "infantile hypertrophic pyloric stenosis type 5",
          "pyloric stenosis, infantile hypertrophic, 5"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0012922"
    },
    {
      "id": 18026,
      "label": "intellectual disability-hypotonia-brachycephaly-pyloric stenosis-cryptorchidism syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16087,
        23979
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0021379",
          "MEDGEN:1655593",
          "Orphanet:314575",
          "UMLS:C4751073"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0017805"
    }
  ],
  "roots": [
    {
      "id": 3765,
      "label": "hypertrophic pyloric stenosis"
    },
    {
      "id": 5714,
      "label": "hereditary disease"
    }
  ]
}