{
  "id": 24049,
  "label": "focal segmental glomerulosclerosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100313",
  "properties": {
    "xrefs": [
      "DOID:1312",
      "EFO:0004236",
      "GARD:0006517",
      "ICD9:582.1",
      "MEDGEN:4904",
      "MESH:D005923",
      "NCIT:C37308",
      "SCTID:236403004",
      "UMLS:C0017668"
    ],
    "synonyms": [
      "FGS (focal glomerular sclerosis)",
      "FSGS",
      "FSGS - focal segmental glomerulosclerosis"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A renal disorder characterized by sclerotic lesions in the glomeruli. Causes include drugs, viruses, and malignancies (lymphomas), or it may be idiopathic. It presents with asymptomatic proteinuria or nephritic syndrome and it may lead to renal failure."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 2948,
      "label": "glomerulosclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19482
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050851",
          "GARD:0022776",
          "MEDGEN:61248",
          "NCIT:C120888",
          "SCTID:197661001",
          "UMLS:C0178664",
          "icd11.foundation:2068645853"
        ],
        "synonyms": [
          "glomerular sclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A hardening of the kidney glomerulus caused by scarring of the blood vessels."
      },
      "child_count": 2,
      "reference_id": "MONDO:0000490"
    }
  ],
  "children": [
    {
      "id": 7046,
      "label": "inherited focal segmental glomerulosclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        23932,
        24049
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0024175",
          "NANDO:1200722",
          "NANDO:2200113",
          "OMIMPS:603278"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "An instance of focal segmental glomerulosclerosis that is caused by an inherited genomic modification in an individual."
      },
      "child_count": 16,
      "reference_id": "MONDO:0005363"
    },
    {
      "id": 24057,
      "label": "primary focal segmental glomerulosclerosis",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24049
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026145",
          "MEDGEN:313617",
          "UMLS:C1709661"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A form of focal segmental glomerulosclerosis without identifiable etiology. Primary (idiopathic) FSGS has been associated with the presence of circulating permeability factors/cytokines, which cause foot process effacement and proteinuria."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100324"
    }
  ],
  "roots": [
    {
      "id": 2948,
      "label": "glomerulosclerosis"
    }
  ]
}