{
  "id": 24051,
  "label": "isolated adrenal insufficiency",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100315",
  "properties": {
    "xrefs": [
      "GARD:0026139"
    ],
    "synonyms": [
      "isolated adrenal insufficiency"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "An ABCD1 deficiency that presents with primary adrenocortical insufficiency between age two years and adulthood and most commonly by age 7.5 years, without evidence of neurologic abnormality; however, some degree of neurologic disability (most commonly adrenomyeloneuropathy (AMN)) usually develops by middle age."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 18561,
      "label": "adrenoleukodystrophy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2902,
        7151,
        16360,
        18952,
        24100
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10588",
          "GARD:0005758",
          "MEDGEN:57667",
          "MESH:D000326",
          "MedDRA:10051260",
          "NANDO:1200165",
          "NANDO:2200576",
          "NCIT:C61252",
          "NORD:736",
          "OMIM:300100",
          "Orphanet:43",
          "UMLS:C0162309",
          "icd11.foundation:1085655586"
        ],
        "synonyms": [
          "ABCD1 deficiency",
          "ALD",
          "Bronze-Schilder disease",
          "Siemerling-Creutzfeldt disease",
          "X-ALD",
          "X-Linked Adrenoleukodystrophy",
          "X-linked ALD",
          "X-linked adrenoleukodystrophy",
          "adrenoleukodystrophy",
          "adrenoleukodystrophy, X-linked",
          "adrenoleukodystrophy, X-linked recessive",
          "adrenomyeloneuropathy, adult",
          "adrenomyeloneuropathy, adult, X-linked recessive",
          "diffuse cerebral sclerosis of Schilder",
          "diffuse sclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A peroxisomal disorder resulting in cerebral demyelination, axonal dysfunction in the spinal cord leading to spastic paraplegia, adrenal insufficiency and in some cases testicular insufficiency."
      },
      "child_count": 15,
      "reference_id": "MONDO:0018544"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 18561,
      "label": "adrenoleukodystrophy"
    }
  ]
}