{
  "id": 24057,
  "label": "primary focal segmental glomerulosclerosis",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100324",
  "properties": {
    "xrefs": [
      "GARD:0026145",
      "MEDGEN:313617",
      "UMLS:C1709661"
    ],
    "categories": [
      {
        "ref": "MONDO:0002118",
        "name": "urinary system disorder"
      }
    ],
    "definition": "A form of focal segmental glomerulosclerosis without identifiable etiology. Primary (idiopathic) FSGS has been associated with the presence of circulating permeability factors/cytokines, which cause foot process effacement and proteinuria."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 24049,
      "label": "focal segmental glomerulosclerosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2948
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1312",
          "EFO:0004236",
          "GARD:0006517",
          "ICD9:582.1",
          "MEDGEN:4904",
          "MESH:D005923",
          "NCIT:C37308",
          "SCTID:236403004",
          "UMLS:C0017668"
        ],
        "synonyms": [
          "FGS (focal glomerular sclerosis)",
          "FSGS",
          "FSGS - focal segmental glomerulosclerosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0002118",
            "name": "urinary system disorder"
          }
        ],
        "definition": "A renal disorder characterized by sclerotic lesions in the glomeruli. Causes include drugs, viruses, and malignancies (lymphomas), or it may be idiopathic. It presents with asymptomatic proteinuria or nephritic syndrome and it may lead to renal failure."
      },
      "child_count": 2,
      "reference_id": "MONDO:0100313"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 24049,
      "label": "focal segmental glomerulosclerosis"
    }
  ]
}