{
  "id": 24290,
  "label": "monogenic alpha thalassemia spectrum",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100565",
  "properties": {
    "xrefs": [
      "GARD:0026284"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "An instance of alpha thalessemia spectrum that is caused by an inherited monogenomic modification in an individual."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 12504,
      "label": "alpha thalassemia spectrum",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3252
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1099",
          "GARD:0000621",
          "ICD10CM:D56.0",
          "ICD9:282.43",
          "ICD9:282.49",
          "MEDGEN:1434",
          "MESH:D017085",
          "MedDRA:10043390",
          "NANDO:2201273",
          "NCIT:C34368",
          "OMIM:604131",
          "Orphanet:846",
          "SCTID:68913001",
          "UMLS:C0002312",
          "icd11.foundation:531667506"
        ],
        "synonyms": [
          "alpha thalassaemia",
          "alpha thalassemia spectrum",
          "alpha-thalassemia",
          "thalassemia, alpha-",
          "thalassemias, alpha-",
          "A-thalassemia",
          "alpha-thalassemia trait"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "An inherited hemoglobinopathy characterized by impaired synthesis of alpha-globin chains leading to a variable clinical picture depending on the number of affected alleles."
      },
      "child_count": 2,
      "reference_id": "MONDO:0011399"
    }
  ],
  "children": [
    {
      "id": 24286,
      "label": "HBA1-related alpha thalassemia spectrum",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24290
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026280"
        ],
        "synonyms": [
          "alpha-thalassemia trait"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Mild microcytic anemia caused by biallelic variation in the HBA1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100561"
    },
    {
      "id": 24287,
      "label": "HBA2-related alpha thalassemia spectrum",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24290
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026281"
        ],
        "synonyms": [
          "alpha-thalassemia trait"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Mild microcytic anemia caused by biallelic variation in the HBA2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0100562"
    }
  ],
  "roots": [
    {
      "id": 12504,
      "label": "alpha thalassemia spectrum"
    }
  ]
}