{
  "id": 24300,
  "label": "hereditary generalized epilepsy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100576",
  "properties": {
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An instance of generalized epilepsy that is caused by an inherited genomic modification in an individual."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 24270,
      "label": "hereditary neurological disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6799
      ],
      "type_id": 0,
      "properties": {
        "synonyms": [
          "neurogenetic disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A heterogeneous group of genetic conditions with Mendelian (autosomal dominant, recessive, or X-linked) or chromosomal etiology characterized by abnormalities in the brain, spinal cord, nerves, or muscles."
      },
      "child_count": 528,
      "reference_id": "MONDO:0100545"
    },
    {
      "id": 24299,
      "label": "genetic generalized epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24298
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1836944",
          "UMLS:C5816885"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A generalized epilepsy that is understood to have a genetic etiology. This does not always mean that the epilepsy is inherited or can be transmitted to offspring, as the genetic etiology may be a de novo pathogenic variant, or the genetic etiology may have complex/polygenic inheritance."
      },
      "child_count": 2,
      "reference_id": "MONDO:0100575"
    }
  ],
  "children": [
    {
      "id": 7224,
      "label": "idiopathic generalized epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24300
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1827",
          "EFO:0005917",
          "MEDGEN:75725",
          "MESH:C562694",
          "OMIM:600669",
          "OMIMPS:600669",
          "SCTID:19598007",
          "UMLS:C0270850"
        ],
        "synonyms": [
          "generalized epilepsy",
          "EIG",
          "IGE",
          "epilepsy, idiopathic generalized",
          "hereditary idiopathic generalized epilepsy",
          "idiopathic generalised epilepsy",
          "idiopathic generalized epilepsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A generalised epilepsy that encompasses several common seizure phenotypes including childhood absence epilepsy, juvenile absence epilepsy, juvenile myoclonic epilepsy and epilepsy with generalized tonic-clonic seizures alone. These epilepsy syndromes have polygenic inheritance with or without environmental factors contributing to seizure susceptibility. Seizure types include one or a combination of absence seizures, myoclonic seizures and/or generalized tonic-clonic seizures."
      },
      "child_count": 2,
      "reference_id": "MONDO:0005579"
    },
    {
      "id": 18347,
      "label": "generalized epilepsy with febrile seizures plus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24300
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060170",
          "GARD:0018641",
          "MEDGEN:503203",
          "MESH:C565808",
          "NCIT:C122811",
          "OMIMPS:604233",
          "Orphanet:36387",
          "SCTID:699688008",
          "UMLS:C3502809"
        ],
        "synonyms": [
          "GEFS+",
          "epilepsy, generalized, with febrile seizures plus",
          "generalised epilepsy with febrile seizures-plus",
          "generalized epilepsy with febrile seizures plus",
          "genetic epilepsy with febrile seizures plus",
          "genetic epilepsy with febrile seizures-plus"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A familial epilepsy syndrome in which family members display a seizure disorder from the generalized epilepsy with febrile seizures plus spectrum which ranges from simple febrile seizures (FS) to the more severe phenotype of myoclonic-astatic epilepsy (MAE) or Dravet syndrome (DS)."
      },
      "child_count": 10,
      "reference_id": "MONDO:0018214"
    }
  ],
  "roots": [
    {
      "id": 24270,
      "label": "hereditary neurological disease"
    },
    {
      "id": 24299,
      "label": "genetic generalized epilepsy"
    }
  ]
}