{
  "id": 24305,
  "label": "ocular growth disorder",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100581",
  "properties": {
    "categories": [
      {
        "ref": "MONDO:0002022",
        "name": "disorder of orbital region"
      },
      {
        "ref": "MONDO:0024458",
        "name": "disorder of visual system"
      }
    ],
    "definition": "An eye disorder characterized by an aberrant development of the eye resulting in significant shortening or elongation, and therefore affecting the final ocular dimensions."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 7,
  "parents": [
    {
      "id": 7019,
      "label": "eye disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4171,
        21415
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:1242",
          "DOID:5614",
          "EFO:0003966",
          "ICD9:360",
          "ICD9:360.29",
          "ICD9:360.89",
          "ICD9:360.9",
          "ICD9:379.8",
          "ICD9:379.90",
          "MEDGEN:5092",
          "MESH:D005128",
          "NCIT:C26767",
          "SCTID:371405004",
          "UMLS:C0015397"
        ],
        "synonyms": [
          "disease of eye",
          "disease of eyeball of camera-type eye",
          "disease or disorder of eyeball of camera-type eye",
          "disorder of eye",
          "disorder of eyeball of camera-type eye",
          "eye disease",
          "eye disorder",
          "eyeball of camera-type eye disease",
          "eyeball of camera-type eye disease or disorder",
          "globe disease",
          "disease of eyeball",
          "disorder of eye proper",
          "disorder of eyeball",
          "disorder of globe"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma."
      },
      "child_count": 240,
      "reference_id": "MONDO:0005328"
    }
  ],
  "children": [
    {
      "id": 3423,
      "label": "pinguecula",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        3218,
        24305
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11029",
          "EFO:1001824",
          "ICD10CM:H11.15",
          "ICD9:372.51",
          "MEDGEN:56273",
          "MESH:D059407",
          "SCTID:87614000",
          "UMLS:C0152255"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A yellowish thickened lesion on the conjunctiva near the cornea representing a benign degenerative change in the conjunctiva caused by the leakage and deposition of certain blood proteins through the permeable capillaries near the limbus."
      },
      "child_count": 0,
      "reference_id": "MONDO:0001179"
    },
    {
      "id": 3606,
      "label": "myopia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        6646,
        24305
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:11830",
          "HP:0000545",
          "ICD10CM:H52.1",
          "ICD9:367.1",
          "MEDGEN:44558",
          "MESH:D009216",
          "OMIMPS:160700",
          "SCTID:57190000",
          "UMLS:C0027092",
          "icd11.foundation:1666440799"
        ],
        "synonyms": [
          "myopia",
          "myopia (disease)",
          "near-sightedness"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "The condition in which the individual does not see far distances clearly."
      },
      "child_count": 90,
      "reference_id": "MONDO:0001384"
    },
    {
      "id": 6813,
      "label": "pterygium",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7676,
        20574,
        24305
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0002116",
          "EFO:0000678",
          "ICD10CM:H11.0",
          "ICD9:372.4",
          "ICD9:372.40",
          "MEDGEN:46202",
          "MESH:D011625",
          "NCIT:C133744",
          "SCTID:77489003",
          "UMLS:C0033999",
          "icd11.foundation:1207385905"
        ],
        "synonyms": [
          "pterygium of conjunctiva and cornea"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A wedge-shaped fibrovascular lesion arising from the bulbar conjunctiva and extending to the cornea. It is caused by chronic exposure to solar ultraviolet radiation, heat, and dust. It may cause severe vision loss. Studies have linked pterygium to neoplastic proliferation and suggest that it may be a stem cell disorder."
      },
      "child_count": 9,
      "reference_id": "MONDO:0005085"
    },
    {
      "id": 16321,
      "label": "keratoconus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3211,
        5714,
        24305
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10126",
          "HP:0000563",
          "ICD10CM:H18.6",
          "ICD9:371.6",
          "ICD9:371.60",
          "MEDGEN:44015",
          "MESH:D007640",
          "MedDRA:10023353",
          "NCIT:C26806",
          "OMIMPS:148300",
          "Orphanet:156071",
          "Orphanet:2335",
          "SCTID:65636009",
          "UMLS:C0022578",
          "icd11.foundation:945228622"
        ],
        "synonyms": [
          "keratoconus",
          "keratoconus (disease)",
          "isolated keratoconus",
          "KC",
          "noninflammatory corneal thining"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "A degenerative, structural disorder of the eye, characterized by a cone-shaped protrusion of the cornea. It may lead to visual disturbances."
      },
      "child_count": 33,
      "reference_id": "MONDO:0015486"
    },
    {
      "id": 19057,
      "label": "Axenfeld-Rieger syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        5714,
        16089,
        20691,
        24305
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:14686",
          "GARD:0005701",
          "ICD9:743.44",
          "MEDGEN:501192",
          "MESH:C535679",
          "MedDRA:10059255",
          "NCIT:C131001",
          "NORD:1670",
          "OMIMPS:180500",
          "Orphanet:782",
          "SCTID:47507006",
          "UMLS:C3495488"
        ],
        "synonyms": [
          "ARS",
          "Axenfeld syndrome",
          "Axenfeldt-Rieger syndrome",
          "Rieger syndrome",
          "goniodysgenesis hypodontia",
          "iridogoniodysgenesis with somatic anomalies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Axenfeld-Rieger syndrome (ARS) is a generic term used to designate overlapping genetic disorders, in which the major physical condition is anterior segment dysgenesis of the eye. Patients with ARS may also present with multiple variable congenital anomalies."
      },
      "child_count": 15,
      "reference_id": "MONDO:0019187"
    },
    {
      "id": 20367,
      "label": "microphthalmia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        24305
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:10629",
          "EFO:0005569",
          "HP:0000568",
          "ICD9:743.1",
          "ICD9:743.10",
          "ICD9:743.11",
          "MEDGEN:10033",
          "MESH:D008850",
          "NCIT:C98989",
          "SCTID:204108000",
          "UMLS:C0026010"
        ],
        "synonyms": [
          "microphthalmia",
          "microphthalmos",
          "nanophthalmos"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Congenital or developmental anomaly in which the eyeballs are abnormally small."
      },
      "child_count": 5,
      "reference_id": "MONDO:0021129"
    },
    {
      "id": 24335,
      "label": "BMP4-related ocular growth disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5714,
        24305
      ],
      "type_id": 0,
      "properties": {
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ],
        "definition": "Any ocular growth disorder in which the cause of the disease is a mutation in the BMP4 gene."
      },
      "child_count": 2,
      "reference_id": "MONDO:0100613"
    }
  ],
  "roots": [
    {
      "id": 7019,
      "label": "eye disorder"
    }
  ]
}