{
  "id": 24354,
  "label": "radiation-induced neuropathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0100635",
  "properties": {
    "xrefs": [
      "ICD10CM:G62.8",
      "SCTID:445339002"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A peripheral neuropathy caused by exposure to radiation, resulting in damage to one or more peripheral nerves."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6950,
      "label": "peripheral neuropathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        5512,
        18957
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:870",
          "EFO:0003100",
          "MEDGEN:18386",
          "MedDRA:10034606",
          "NCIT:C119734",
          "NCIT:C4731",
          "SCTID:302226006",
          "SCTID:386033004",
          "UMLS:C0031117"
        ],
        "synonyms": [
          "neuropathy",
          "peripheral nerve disorder",
          "peripheral neuropathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder affecting the peripheral nervous system. It manifests with pain, tingling, numbness, and muscle weakness. It may be the result of physical injury, toxic substances, viral diseases, diabetes, renal failure, cancer, and drugs."
      },
      "child_count": 60,
      "reference_id": "MONDO:0005244"
    },
    {
      "id": 23212,
      "label": "radiation-induced disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29383
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0009565",
          "GARD:0022139",
          "MEDGEN:734320",
          "MESH:D000016",
          "NCIT:C26684",
          "Orphanet:521132",
          "SCTID:85983004",
          "UMLS:C1527225"
        ],
        "synonyms": [
          "radiation-induced Abnormality",
          "radiation-induced abnormalities",
          "radiation-induced disorder",
          "Abnormality, radiation-induced",
          "abnormalities, radiation induced",
          "radiation induced abnormalities"
        ],
        "definition": "A non-neoplastic or neoplastic disorder which results from exposure to radiation. Examples of non-neoplastic disorders include dermatitis, enteritis, stomatitis, pneumonitis, and cerebritis. Examples of neoplastic disorders include myelodysplastic syndromes, leukemias, and sarcomas."
      },
      "child_count": 8,
      "reference_id": "MONDO:0043459"
    }
  ],
  "children": [
    {
      "id": 22746,
      "label": "radiation-induced plexopathy",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16613,
        21410,
        24354
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022137",
          "MEDGEN:1809151",
          "Orphanet:521123",
          "UMLS:C5681446"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A rare radiation-induced disorder characterized by impairment of the peripheral nervous system at the level of the brachial or lumbosacral plexus following radiation therapy. Onset of symptoms can occur between several months up to decades after the last dose of radiation. Patients with radiation-induced brachial plexopathy typically present with mostly unilateral progressive paresthesia, followed by weakness, atrophy, and pain. Symptoms in radiation-induced lumbosacral plexopathy include more variable combinations of numbness, paresthesia, pain, and weakness, and are more often bilateral."
      },
      "child_count": 0,
      "reference_id": "MONDO:0033838"
    }
  ],
  "roots": [
    {
      "id": 6950,
      "label": "peripheral neuropathy"
    },
    {
      "id": 23212,
      "label": "radiation-induced disorder"
    }
  ]
}