{
  "id": 24397,
  "label": "B-cell acute lymphoblastic leukemia with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1)",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0600030",
  "properties": {
    "xrefs": [
      "DOID:0080649",
      "GARD:0022348",
      "MEDGEN:396324",
      "NCIT:C80347",
      "Orphanet:585956",
      "SCTID:450956008",
      "UMLS:C2698315"
    ],
    "synonyms": [
      "B acute lymphoblastic leukaemia with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1)",
      "B acute lymphoblastic leukemia with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1)",
      "B lymphoblastic leukaemia lymphoma with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1) (morphologic abnormality)",
      "B lymphoblastic leukemia lymphoma with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1) (morphologic abnormality)",
      "B-acute lymphoblastic leukaemia with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1)",
      "B-acute lymphoblastic leukemia with t(1;19)(q23;p13.3); E2A-PBX1 (TCF3-PBX1)",
      "B-lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3)"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ],
    "definition": "A B-cell acute leukemia characterized by the presence of lymphoblasts that carry a translocation between the E2A gene on chromosome 19 and the PBX1 gene on chromosome 1. It occurs in children and less often in adults."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6692,
      "label": "B-cell acute lymphoblastic leukemia",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6710,
        16516
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080630",
          "DOID:7061",
          "EFO:0000094",
          "GARD:0024135",
          "MEDGEN:226949",
          "NCIT:C8936",
          "SCTID:277571004",
          "UMLS:C1292769"
        ],
        "synonyms": [
          "B lymphoblastic leukemia/lymphoma",
          "precursor B lymphoblastic leukemia/lymphoma",
          "precursor B-lymphoblastic lymphoma/leukemia",
          "precursor B lymphoblastic lymphoma/leukemia"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A neoplasm of lymphoblasts committed to the B-cell lineage, typically composed of small to medium-sized blast cells. When the neoplasm involves predominantly the bone marrow and the peripheral blood, it is called B acute lymphoblastic leukemia. When it involves nodal or extranodal sites, it is called B lymphoblastic lymphoma. (WHO, 2001)"
      },
      "child_count": 32,
      "reference_id": "MONDO:0004947"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6692,
      "label": "B-cell acute lymphoblastic leukemia"
    }
  ]
}