{
  "id": 24476,
  "label": "EPHB4-associated vascular malformation spectrum",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0700080",
  "properties": {
    "categories": [
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "Any vascular malformation in which the cause of the disease is a variation in the EPHB4 gene."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    },
    {
      "id": 21326,
      "label": "vascular malformation",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        7065
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:0006888",
          "MEDGEN:56387",
          "MESH:D054079",
          "NANDO:2100295",
          "UMLS:C0158570"
        ],
        "synonyms": [
          "vascular malformation",
          "malformation, vascular",
          "malformations, vascular"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A non-neoplastic disorder that is the result of defects of vascular morphogenesis."
      },
      "child_count": 6,
      "reference_id": "MONDO:0024291"
    }
  ],
  "children": [
    {
      "id": 15985,
      "label": "lymphatic malformation 7",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19154,
        24476
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0025049",
          "MEDGEN:934596",
          "OMIM:617300",
          "UMLS:C4310629"
        ],
        "synonyms": [
          "HFASD",
          "hydrops fetalis, nonimmune, and/or atrial septal defect, susceptibility to",
          "hydrops fetalis, nonimmune, and/or atrial septal defect, susceptibility to; HFASD"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0015009"
    },
    {
      "id": 20185,
      "label": "capillary malformation-arteriovenous malformation 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        13087,
        24476
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0016307",
          "MEDGEN:1648502",
          "OMIM:618196",
          "Orphanet:693912",
          "UMLS:C4748670"
        ],
        "synonyms": [
          "CAPILLARY MALFORMATION-ARTERIOVENOUS MALFORMATION 2",
          "CMAVM2"
        ],
        "categories": [
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0020785"
    }
  ],
  "roots": [
    {
      "id": 5714,
      "label": "hereditary disease"
    },
    {
      "id": 21326,
      "label": "vascular malformation"
    }
  ]
}