{
  "id": 24478,
  "label": "Robertsonian translocation Down syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0700082",
  "properties": {
    "xrefs": [
      "GARD:0026350",
      "MEDGEN:1816520",
      "NCIT:C188150",
      "UMLS:C5707615"
    ],
    "definition": "Chromosomal disorder in which (part or full) chromosome 21 is attached to another chromosome, resulting in the presence of a third copy of part of full chromosome 21 genetic material. A Robertsonian translocation is a structural chromosomal anomaly in which two acrocentric chromosomes break, resulting in the fusion of the nonhomologous chromosomes’ long arms to form a single, large chromosome."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 24523,
      "label": "translocation Down syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        9893
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026369",
          "MEDGEN:693553",
          "UMLS:C1269751"
        ],
        "synonyms": [
          "Robertsonian Translocation Trisomy 21"
        ],
        "definition": "Down syndrome in which the extra (partial or total) copy of chromosome 21 genetic material is attached to another chromosome."
      },
      "child_count": 3,
      "reference_id": "MONDO:0700128"
    }
  ],
  "children": [
    {
      "id": 24489,
      "label": "balanced Robertsonian translocation Down syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24478
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026358"
        ],
        "definition": "Robertsonian translocation Down syndrome in which translocation displacement of the end regions of chromosomes occurred without loss of chromosomal material between the two nonhomologous chromosomes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0700093"
    },
    {
      "id": 24490,
      "label": "unbalanced Robertsonian translocation Down syndrome",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24478
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026359"
        ],
        "definition": "Robertsonian translocation Down syndrome in which translocation displacement of the end regions of chromosomes occurred with loss of chromosomal material between the two nonhomologous chromosomes."
      },
      "child_count": 0,
      "reference_id": "MONDO:0700094"
    }
  ],
  "roots": [
    {
      "id": 24523,
      "label": "translocation Down syndrome"
    }
  ]
}