{
  "id": 24486,
  "label": "epilepsy, familial temporal lobe, 1",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0700090",
  "properties": {
    "xrefs": [
      "DOID:0060748",
      "GARD:0026356",
      "NCIT:C141441",
      "OMIM:600512"
    ],
    "synonyms": [
      "ADLTE",
      "ADPEAF",
      "ETL1",
      "epilepsy, familial temporal lobe, type 1",
      "epilepsy, lateral temporal lobe, autosomal dominant",
      "epilepsy, partial, with auditory features"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An autosomal dominant condition caused by mutation(s) in the LGI1 gene, encoding leucine-rich glioma-inactivated protein 1. It is characterized by partial seizures originating in the temporal lobe and often accompanied by auditory sensory manifestations."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6841,
      "label": "temporal lobe epilepsy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        17942
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3328",
          "EFO:0000773",
          "GARD:0005135",
          "MEDGEN:4990",
          "MESH:D004833",
          "NCIT:C177244",
          "OMIMPS:600512",
          "Orphanet:98819",
          "SCTID:193000002",
          "SCTID:783739005",
          "UMLS:C0014556",
          "birnlex:12733"
        ],
        "synonyms": [
          "epilepsy of temporal lobe",
          "epilepsy, familial temporal lobe",
          "familial temporal lobe epilepsy syndrome",
          "temporal lobe epilepsy"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the temporal lobe, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see epilepsy, complex partial) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic (i.e., related to an identified disease process or lesion). (From Adams et al., Principles of Neurology, 6th ed, p321)"
      },
      "child_count": 6,
      "reference_id": "MONDO:0005115"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6841,
      "label": "temporal lobe epilepsy"
    }
  ]
}