{
  "id": 24709,
  "label": "familial isolated dilated cardiomyopathy",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0700335",
  "properties": {
    "xrefs": [
      "GARD:0027293",
      "MEDGEN:1826005",
      "Orphanet:154",
      "UMLS:C5679590",
      "icd11.foundation:949016860"
    ],
    "synonyms": [
      "familial isolated dilated cardiomyopathy",
      "familial or idiopathic dilated cardiomyopathy"
    ],
    "categories": [
      {
        "ref": "MONDO:0002081",
        "name": "musculoskeletal system disorder"
      },
      {
        "ref": "MONDO:0004995",
        "name": "cardiovascular disorder"
      }
    ],
    "definition": "A rare familial cardiomyopathy characterized by the dilation of left ventricle and progressively impairing of systolic ventricular function, in the absence of abnormal loading conditions or coronary artery disease sufficient to cause global systolic impairment. The disease may cause heart failure or arrhythmia. The disease is isolated when no additional atypical cardiac or extracardiac manifestations are present."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 45,
  "parents": [
    {
      "id": 16878,
      "label": "familial dilated cardiomyopathy",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6757,
        6933
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020525",
          "MEDGEN:90951",
          "MESH:C536231",
          "OMIMPS:115200",
          "Orphanet:217607",
          "UMLS:C0340427",
          "icd11.foundation:423719003"
        ],
        "synonyms": [
          "hereditary dilated cardiomyopathy",
          "DCM",
          "dilated cardiomyopathy, familial",
          "hypokinetic dilated cardiomyopathy, familial",
          "idiopathic dilated cardiomyopathy"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A a genetic form of heart disease that occurs when heart (cardiac) muscle becomes thin and weakened in at least one chamber of the heart, causing the open area of the chamber to become enlarged (dilated). As a result, the heart is unable to pump blood as efficiently as usual. To compensate, the heart attempts to increase the amount of blood being pumped through the heart, leading to further thinning and weakening of the cardiac muscle. Over time, this condition results in heart failure."
      },
      "child_count": 58,
      "reference_id": "MONDO:0016333"
    }
  ],
  "children": [
    {
      "id": 8671,
      "label": "dilated cardiomyopathy 1A",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110425",
          "GARD:0018615",
          "MEDGEN:1875382",
          "OMIM:115200",
          "Orphanet:300751",
          "SCTID:766883006",
          "UMLS:C5979868",
          "icd11.foundation:884022112"
        ],
        "synonyms": [
          "CDCD1",
          "LMNA familial isolated dilated cardiomyopathy",
          "cardiomyopathy dilated with conduction defect type 1",
          "cardiomyopathy, dilated, type 1A",
          "dilated cardiomyopathy 1A",
          "dilated cardiomyopathy type 1A",
          "familial dilated cardiomyopathy with conduction defect due to LMNA mutation",
          "familial isolated dilated cardiomyopathy caused by mutation in LMNA",
          "cardiomyopathy, congestive",
          "cardiomyopathy, dilated, 1A",
          "cardiomyopathy, dilated, with conduction defect 1",
          "cardiomyopathy, familial idiopathic",
          "cardiomyopathy, idiopathic dilated"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007269"
    },
    {
      "id": 11697,
      "label": "dilated cardiomyopathy 3B",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16752,
        24270,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0060561",
          "DOID:0081164",
          "DOID:0110461",
          "GARD:0015287",
          "ICD9:425.4",
          "MEDGEN:777148",
          "MESH:C580047",
          "OMIM:302045",
          "SCTID:702424003",
          "UMLS:C3668940"
        ],
        "synonyms": [
          "CMD3B",
          "DMD dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 3B",
          "dilated cardiomyopathy 3B",
          "dilated cardiomyopathy caused by mutation in DMD",
          "dilated cardiomyopathy type 3B",
          "DMD-related dilated cardiomyopathy",
          "X-linked dilated cardiomyopathy",
          "cardiomyopathy, dilated, 3B",
          "cardiomyopathy, dilated, X-linked"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any dilated cardiomyopathy in which the cause of the disease is a mutation in the DMD gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010542"
    },
    {
      "id": 12081,
      "label": "dilated cardiomyopathy 1B",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110443",
          "GARD:0015323",
          "MEDGEN:1814491",
          "OMIM:600884",
          "UMLS:C5700078"
        ],
        "synonyms": [
          "cardiomyopathy, dilated 1B",
          "dilated cardiomyopathy type 1B",
          "cardiomyopathy, dilated, 1B",
          "cardiomyopathy, familial dilated",
          "cardiomyopathy, familial dilated, 1"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that has material basis in variation in the chromosome region 9q13."
      },
      "child_count": 0,
      "reference_id": "MONDO:0010951"
    },
    {
      "id": 12129,
      "label": "dilated cardiomyopathy 1E",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4370,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110433",
          "GARD:0005644",
          "MEDGEN:331341",
          "MESH:C563384",
          "OMIM:601154",
          "UMLS:C1832680"
        ],
        "synonyms": [
          "CDCD2",
          "CMD1E",
          "SCN5A familial isolated dilated cardiomyopathy",
          "cardiomyopathy dilated with conduction defect type 2",
          "cardiomyopathy, dilated, 1E",
          "cardiomyopathy, dilated, type 1E",
          "cardiomyopathy, dilated, with conduction defect 2",
          "cardiomyopathy, dilated, with conduction disorder and arrhythmia",
          "dilated cardiomyopathy type 1E",
          "familial isolated dilated cardiomyopathy caused by mutation in SCN5A"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the SCN5A gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011003"
    },
    {
      "id": 12220,
      "label": "dilated cardiomyopathy 1C",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18829,
        21518,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110423",
          "GARD:0015331",
          "MEDGEN:316944",
          "MESH:C563307",
          "NCIT:C170436",
          "OMIM:601493",
          "UMLS:C1832244"
        ],
        "synonyms": [
          "cardiomyopathy, dilated, 1C, with or without LVNC",
          "cardiomyopathy, hypertrophic, 24",
          "dilated cardiomyopathy type 1C",
          "CMD1C",
          "cardiomyopathy, dilated, 1C, with or without left ventricular noncompaction",
          "cardiomyopathy, familial hypertrophic, 24",
          "left ventricular noncompaction 3"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that has material basis in mutation in the LDB3 gene on chromosome 10q23.2."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011094"
    },
    {
      "id": 12221,
      "label": "dilated cardiomyopathy 1D",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18829,
        24709,
        26612
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110426",
          "GARD:0015332",
          "MEDGEN:316943",
          "MESH:C563306",
          "OMIM:601494",
          "UMLS:C1832243"
        ],
        "synonyms": [
          "CMD1D",
          "TNNT2 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1D",
          "dilated cardiomyopathy 1D",
          "dilated cardiomyopathy type 1D",
          "familial isolated dilated cardiomyopathy caused by mutation in TNNT2",
          "cardiomyopathy, dilated, 1D",
          "left ventricular noncompaction 6"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the TNNT2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011095"
    },
    {
      "id": 12505,
      "label": "dilated cardiomyopathy 1G",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24220,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110430",
          "GARD:0015363",
          "MEDGEN:347714",
          "MESH:C565824",
          "OMIM:604145",
          "UMLS:C1858763"
        ],
        "synonyms": [
          "CMD1G",
          "TTN familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1G",
          "dilated cardiomyopathy type 1G",
          "familial isolated dilated cardiomyopathy caused by mutation in TTN",
          "cardiomyopathy, dilated, 1G"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the TTN gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011400"
    },
    {
      "id": 12530,
      "label": "dilated cardiomyopathy 1H",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110429",
          "GARD:0015365",
          "MEDGEN:348980",
          "MESH:C536277",
          "OMIM:604288",
          "UMLS:C1858591"
        ],
        "synonyms": [
          "CMD1H",
          "dilated cardiomyopathy type 1H",
          "cardiomyopathy, dilated, 1H",
          "cardiomyopathy, dilated, with conduction defect"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that has material basis in variation in the chromosome region 2q14-q22."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011425"
    },
    {
      "id": 12584,
      "label": "dilated cardiomyopathy 1I",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16774,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110431",
          "GARD:0015372",
          "MEDGEN:387998",
          "MESH:C565752",
          "OMIM:604765",
          "UMLS:C1858154"
        ],
        "synonyms": [
          "CMD1I",
          "DES familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1I",
          "dilated cardiomyopathy type 1I",
          "familial isolated dilated cardiomyopathy caused by mutation in DES",
          "cardiomyopathy, dilated, 1I"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the DES gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011482"
    },
    {
      "id": 12663,
      "label": "dilated cardiomyopathy 1K",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110437",
          "GARD:0015382",
          "MEDGEN:381354",
          "MESH:C565320",
          "OMIM:605582",
          "UMLS:C1854159"
        ],
        "synonyms": [
          "CMD1K",
          "dilated cardiomyopathy type 1K",
          "cardiomyopathy, dilated, 1K"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that has material basis in variation in the chromosome region 6q12-q16."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011567"
    },
    {
      "id": 12791,
      "label": "dilated cardiomyopathy 1L",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16749,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110436",
          "GARD:0015397",
          "MEDGEN:335735",
          "MESH:C564679",
          "OMIM:606685",
          "UMLS:C1847667"
        ],
        "synonyms": [
          "CMD1L",
          "SGCD familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1L",
          "dilated cardiomyopathy type 1L",
          "familial isolated dilated cardiomyopathy caused by mutation in SGCD",
          "cardiomyopathy, dilated, 1L"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the SGCD gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011702"
    },
    {
      "id": 12921,
      "label": "dilated cardiomyopathy 1M",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110449",
          "GARD:0015413",
          "MEDGEN:334498",
          "MESH:C564390",
          "OMIM:607482",
          "UMLS:C1843808"
        ],
        "synonyms": [
          "CMD1M",
          "CSRP3 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1M",
          "dilated cardiomyopathy type 1M",
          "familial isolated dilated cardiomyopathy caused by mutation in CSRP3",
          "cardiomyopathy, dilated, 1M"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the CSRP3 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0011840"
    },
    {
      "id": 13130,
      "label": "dilated cardiomyopathy 1O",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110451",
          "GARD:0015434",
          "MEDGEN:325268",
          "MESH:C563906",
          "OMIM:608569",
          "UMLS:C1837839"
        ],
        "synonyms": [
          "ABCC9 familial isolated dilated cardiomyopathy",
          "CMD1O",
          "cardiomyopathy, dilated, type 1O",
          "dilated cardiomyopathy type 1O",
          "familial isolated dilated cardiomyopathy caused by mutation in ABCC9",
          "cardiomyopathy, dilated, 1O",
          "cardiomyopathy, dilated, with ventricular tachycardia"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the ABCC9 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012062"
    },
    {
      "id": 13414,
      "label": "dilated cardiomyopathy 1P",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110439",
          "GARD:0015469",
          "MEDGEN:322782",
          "MESH:C563690",
          "OMIM:609909",
          "UMLS:C1835928"
        ],
        "synonyms": [
          "CMD1P",
          "PLN familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, 1P",
          "cardiomyopathy, dilated, type 1P",
          "dilated cardiomyopathy type 1P",
          "familial isolated dilated cardiomyopathy caused by mutation in PLN"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the PLN gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012362"
    },
    {
      "id": 13416,
      "label": "dilated cardiomyopathy 1Q",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110442",
          "GARD:0015470",
          "MEDGEN:332088",
          "MESH:C563688",
          "OMIM:609915",
          "UMLS:C1835926"
        ],
        "synonyms": [
          "CMD1Q",
          "dilated cardiomyopathy type 1Q",
          "cardiomyopathy, dilated, 1Q"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that has material basis in variation in the chromosome region 7q22.3-q31.1."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012364"
    },
    {
      "id": 13707,
      "label": "dilated cardiomyopathy 1W",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110446",
          "GARD:0015515",
          "MEDGEN:370063",
          "MESH:C566954",
          "OMIM:611407",
          "UMLS:C1969639"
        ],
        "synonyms": [
          "CMD1W",
          "VCL familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1W",
          "dilated cardiomyopathy type 1W",
          "familial isolated dilated cardiomyopathy caused by mutation in VCL",
          "cardiomyopathy, dilated, 1W"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the VCL gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012667"
    },
    {
      "id": 13744,
      "label": "dilated cardiomyopathy 1X",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110444",
          "GARD:0015522",
          "MEDGEN:370583",
          "MESH:C566907",
          "OMIM:611615",
          "UMLS:C1969024"
        ],
        "synonyms": [
          "CMD1X",
          "FKTN familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1X",
          "dilated cardiomyopathy type 1X",
          "familial isolated dilated cardiomyopathy caused by mutation in FKTN",
          "cardiomyopathy, dilated, 1X",
          "cardiomyopathy, dilated, with mild or No proximal muscle weakness"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the FKTN gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012704"
    },
    {
      "id": 13784,
      "label": "dilated cardiomyopathy 1Y",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18829,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110457",
          "GARD:0015530",
          "MEDGEN:437215",
          "MESH:C567507",
          "OMIM:611878",
          "UMLS:C2678476"
        ],
        "synonyms": [
          "CMD1Y",
          "TPM1 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Y",
          "dilated cardiomyopathy type 1Y",
          "familial isolated dilated cardiomyopathy caused by mutation in TPM1",
          "cardiomyopathy, dilated, 1Y",
          "left ventricular noncompaction 9"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the TPM1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012744"
    },
    {
      "id": 13785,
      "label": "dilated cardiomyopathy 1Z",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110434",
          "GARD:0015531",
          "MEDGEN:395631",
          "MESH:C567506",
          "OMIM:611879",
          "UMLS:C2678475"
        ],
        "synonyms": [
          "CMD1Z",
          "TNNC1 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Z",
          "dilated cardiomyopathy type 1Z",
          "familial isolated dilated cardiomyopathy caused by mutation in TNNC1",
          "cardiomyopathy, dilated, 1Z"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the TNNC1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012745"
    },
    {
      "id": 13786,
      "label": "dilated cardiomyopathy 2A",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110460",
          "GARD:0015532",
          "MEDGEN:437214",
          "OMIM:611880",
          "UMLS:C2678474"
        ],
        "synonyms": [
          "CMD2A",
          "cardiomyopathy, dilated, type 2A",
          "dilated cardiomyopathy type 2A",
          "cardiomyopathy, congestive, autosomal recessive",
          "cardiomyopathy, dilated, 2A",
          "cardiomyopathy, dilated, autosomal recessive"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that has material basis in mutation in the TNNI3 gene on chromosome 19q13."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012746"
    },
    {
      "id": 13848,
      "label": "dilated cardiomyopathy 1AA",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709,
        24723
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110428",
          "GARD:0015543",
          "MEDGEN:393713",
          "MESH:C567407",
          "OMIM:612158",
          "UMLS:C2677338"
        ],
        "synonyms": [
          "ACTN2 familial isolated dilated cardiomyopathy",
          "CMD1AA",
          "cardiomyopathy, dilated, 1AA, with or without LVNC",
          "cardiomyopathy, hypertrophic, 23, with or without LVNC",
          "dilated cardiomyopathy type 1AA",
          "familial isolated dilated cardiomyopathy caused by mutation in ACTN2",
          "cardiomyopathy, dilated, 1AA, with or without left ventricular noncompaction",
          "cardiomyopathy, familial hypertrophic, 23, with or without ventricular noncompaction"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the ACTN2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0012808"
    },
    {
      "id": 14068,
      "label": "dilated cardiomyopathy 1BB",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110458",
          "GARD:0015588",
          "MEDGEN:414552",
          "MESH:C567877",
          "OMIM:612877",
          "UMLS:C2752072"
        ],
        "synonyms": [
          "CMD1BB",
          "DSG2 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Bb",
          "dilated cardiomyopathy type 1BB",
          "familial isolated dilated cardiomyopathy caused by mutation in DSG2",
          "cardiomyopathy, dilated, 1BB"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the DSG2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013030"
    },
    {
      "id": 14183,
      "label": "dilated cardiomyopathy 1CC",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110424",
          "GARD:0015621",
          "MEDGEN:413929",
          "MESH:C567733",
          "OMIM:613122",
          "UMLS:C2751084"
        ],
        "synonyms": [
          "CMD1CC",
          "NEXN familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Cc",
          "dilated cardiomyopathy type 1CC",
          "familial isolated dilated cardiomyopathy caused by mutation in NEXN",
          "cardiomyopathy, dilated, 1CC"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the NEXN gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013147"
    },
    {
      "id": 14204,
      "label": "dilated cardiomyopathy 1DD",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110447",
          "GARD:0015627",
          "MEDGEN:416441",
          "MESH:C567725",
          "OMIM:613172",
          "UMLS:C2750995"
        ],
        "synonyms": [
          "CMD1DD",
          "RBM20 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Dd",
          "dilated cardiomyopathy type 1DD",
          "familial isolated dilated cardiomyopathy caused by mutation in RBM20",
          "cardiomyopathy, dilated, 1DD"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the RBM20 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013168"
    },
    {
      "id": 14234,
      "label": "dilated cardiomyopathy 1EE",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110453",
          "GARD:0015639",
          "MEDGEN:412965",
          "MESH:C567683",
          "OMIM:613252",
          "UMLS:C2750466"
        ],
        "synonyms": [
          "CMD1EE",
          "MYH6 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Ee",
          "dilated cardiomyopathy type 1EE",
          "familial isolated dilated cardiomyopathy caused by mutation in MYH6",
          "cardiomyopathy, dilated, 1EE"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the MYH6 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013198"
    },
    {
      "id": 14247,
      "label": "dilated cardiomyopathy 1FF",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110459",
          "GARD:0015643",
          "MEDGEN:412876",
          "MESH:C567654",
          "OMIM:613286",
          "UMLS:C2750091"
        ],
        "synonyms": [
          "CMD1FF",
          "cardiomyopathy, dilated, type 1Ff",
          "dilated cardiomyopathy type 1FF",
          "cardiomyopathy, dilated, 1FF"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that has material basis in mutation in the TNNI3 gene on chromosome 19q13.42."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013211"
    },
    {
      "id": 14297,
      "label": "dilated cardiomyopathy 1R",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18829,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110456",
          "GARD:0015661",
          "MEDGEN:462031",
          "OMIM:613424",
          "UMLS:C3150681"
        ],
        "synonyms": [
          "ACTC1 familial isolated dilated cardiomyopathy",
          "CMD1R",
          "cardiomyopathy, dilated, type 1R",
          "dilated cardiomyopathy type 1R",
          "familial isolated dilated cardiomyopathy caused by mutation in ACTC1",
          "cardiomyopathy, dilated, 1R",
          "left ventricular noncompaction 4"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the ACTC1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013261"
    },
    {
      "id": 14298,
      "label": "dilated cardiomyopathy 1S",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18829,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110454",
          "GARD:0012832",
          "MEDGEN:371831",
          "MESH:C563538",
          "OMIM:613426",
          "UMLS:C1834481"
        ],
        "synonyms": [
          "CMD1S",
          "MYH7 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1S",
          "dilated cardiomyopathy type 1S",
          "familial isolated dilated cardiomyopathy caused by mutation in MYH7",
          "cardiomyopathy, dilated, 1S",
          "dilated cardiomyopathy-1S",
          "left ventricular noncompaction 5"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the MYH7 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013262"
    },
    {
      "id": 14374,
      "label": "dilated cardiomyopathy 1GG",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110435",
          "GARD:0015684",
          "MEDGEN:462248",
          "OMIM:613642",
          "UMLS:C3150898"
        ],
        "synonyms": [
          "CMD1GG",
          "SDHA familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Gg",
          "dilated cardiomyopathy type 1GG",
          "familial isolated dilated cardiomyopathy caused by mutation in SDHA",
          "cardiomyopathy, dilated, 1GG"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the SDHA gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013339"
    },
    {
      "id": 14404,
      "label": "dilated cardiomyopathy 1U",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110455",
          "GARD:0015689",
          "MEDGEN:463620",
          "MESH:C566296",
          "OMIM:613694",
          "UMLS:C3160720"
        ],
        "synonyms": [
          "CMD1U",
          "PSEN1 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1U",
          "dilated cardiomyopathy type 1U",
          "familial isolated dilated cardiomyopathy caused by mutation in PSEN1",
          "cardiomyopathy, dilated, 1U"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the PSEN1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013371"
    },
    {
      "id": 14406,
      "label": "dilated cardiomyopathy 1V",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110427",
          "GARD:0015690",
          "MEDGEN:462308",
          "MESH:C566856",
          "OMIM:613697",
          "UMLS:C3150958"
        ],
        "synonyms": [
          "CMD1V",
          "PSEN2 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1V",
          "dilated cardiomyopathy type 1V",
          "familial isolated dilated cardiomyopathy caused by mutation in PSEN2",
          "cardiomyopathy, dilated, 1V"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the PSEN2 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013373"
    },
    {
      "id": 14510,
      "label": "dilated cardiomyopathy 1HH",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110448",
          "GARD:0015726",
          "MEDGEN:462643",
          "OMIM:613881",
          "UMLS:C3151293"
        ],
        "synonyms": [
          "BAG3 familial isolated dilated cardiomyopathy",
          "CMD1HH",
          "cardiomyopathy, dilated, type 1Hh",
          "dilated cardiomyopathy type 1HH",
          "familial isolated dilated cardiomyopathy caused by mutation in BAG3",
          "cardiomyopathy, dilated, 1HH"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the BAG3 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013479"
    },
    {
      "id": 14862,
      "label": "dilated cardiomyopathy 2B",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110441",
          "GARD:0015832",
          "MEDGEN:766323",
          "OMIM:614672",
          "UMLS:C3553409"
        ],
        "synonyms": [
          "CMD2B",
          "GATAD1 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 2B",
          "dilated cardiomyopathy 2B",
          "dilated cardiomyopathy type 2B",
          "familial isolated dilated cardiomyopathy caused by mutation in GATAD1",
          "cardiomyopathy, dilated, 2B"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the GATAD1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0013848"
    },
    {
      "id": 15082,
      "label": "dilated cardiomyopathy 1II",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709,
        29370
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110450",
          "GARD:0015916",
          "MEDGEN:767563",
          "OMIM:615184",
          "UMLS:C3554649"
        ],
        "synonyms": [
          "CMD1II",
          "CRYAB familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1II",
          "dilated cardiomyopathy type 1II",
          "familial isolated dilated cardiomyopathy caused by mutation in CRYAB",
          "cardiomyopathy, dilated, 1II"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the CRYAB gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014073"
    },
    {
      "id": 15104,
      "label": "dilated cardiomyopathy 1JJ",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110438",
          "GARD:0015924",
          "MEDGEN:815265",
          "OMIM:615235",
          "UMLS:C3808935"
        ],
        "synonyms": [
          "CMD1JJ",
          "LAMA4 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Jj",
          "dilated cardiomyopathy type 1JJ",
          "familial isolated dilated cardiomyopathy caused by mutation in LAMA4",
          "cardiomyopathy, dilated, 1JJ"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the LAMA4 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014095"
    },
    {
      "id": 15109,
      "label": "dilated cardiomyopathy 1KK",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16880,
        21518,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110445",
          "GARD:0015926",
          "MEDGEN:811544",
          "OMIM:615248",
          "UMLS:C3714995"
        ],
        "synonyms": [
          "CMD1KK",
          "MYPN dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Kk",
          "cardiomyopathy, hypertrophic, 22",
          "dilated cardiomyopathy caused by mutation in MYPN",
          "dilated cardiomyopathy type 1KK",
          "cardiomyopathy, dilated, 1KK",
          "cardiomyopathy, familial hypertrophic, 22",
          "cardiomyopathy, familial restrictive, 4"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any dilated cardiomyopathy in which the cause of the disease is a mutation in the MYPN gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014100"
    },
    {
      "id": 15159,
      "label": "left ventricular noncompaction 8",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18829,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081157",
          "GARD:0015952",
          "MEDGEN:815618",
          "OMIM:615373",
          "UMLS:C3809288"
        ],
        "synonyms": [
          "PRDM16 familial isolated dilated cardiomyopathy",
          "familial isolated dilated cardiomyopathy caused by mutation in PRDM16",
          "left ventricular noncompaction 8",
          "left ventricular noncompaction type 8",
          "LVNC8",
          "cardiomyopathy, dilated, 1Ll"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the PRDM16 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014152"
    },
    {
      "id": 15170,
      "label": "left ventricular noncompaction 10",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18829,
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0015956",
          "MEDGEN:811617",
          "OMIM:615396",
          "UMLS:C3715165"
        ],
        "synonyms": [
          "MYBPC3 left ventricular noncompaction",
          "left ventricular noncompaction 10",
          "left ventricular noncompaction caused by mutation in MYBPC3",
          "left ventricular noncompaction type 10",
          "LVNC10",
          "cardiomyopathy, dilated, 1Mm"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any left ventricular noncompaction in which the cause of the disease is a mutation in the MYBPC3 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014163"
    },
    {
      "id": 15398,
      "label": "dilated cardiomyopathy 1NN",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110432",
          "GARD:0016031",
          "MEDGEN:863093",
          "OMIM:615916",
          "UMLS:C4014656"
        ],
        "synonyms": [
          "CMD1NN",
          "RAF1 familial isolated dilated cardiomyopathy",
          "cardiomyopathy, dilated, type 1Nn",
          "dilated cardiomyopathy type 1NN",
          "familial isolated dilated cardiomyopathy caused by mutation in RAF1",
          "cardiomyopathy, dilated, 1NN"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "Any familial isolated dilated cardiomyopathy in which the cause of the disease is a mutation in the RAF1 gene."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014396"
    },
    {
      "id": 21871,
      "label": "cardiomyopathy, dilated, 2D",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081160",
          "GARD:0025531",
          "MEDGEN:1782612",
          "OMIM:619371",
          "UMLS:C5543535"
        ],
        "synonyms": [
          "CMD2D",
          "cardiomyopathy, dilated, 2D"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that is characterized by neonatal onset of severe cardiomyopathy, with rapid progression to cardiac decompensation and death unless the patient undergoes heart transplantation and that has material basis in homozygous or compound heterozygous mutation in the RPL3L gene on chromosome 16p13."
      },
      "child_count": 0,
      "reference_id": "MONDO:0030300"
    },
    {
      "id": 21904,
      "label": "cardiomyopathy, dilated, 2E",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081161",
          "GARD:0025554",
          "MEDGEN:1794180",
          "OMIM:619492",
          "UMLS:C5561970"
        ],
        "synonyms": [
          "CMD2E",
          "cardiomyopathy, dilated, 2E"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that is characterized by neonatal or early childhood onset of dilated cardiomyopathy, with rapid progression to cardiac failure and death unless patients undergo cardiac transplantation and that has material basis in homozygous or compound heterozygous mutation in the JPH2 gene on chromosome 20q13."
      },
      "child_count": 0,
      "reference_id": "MONDO:0030366"
    },
    {
      "id": 21997,
      "label": "cardiomyopathy, dilated, 2F",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081162",
          "GARD:0025609",
          "MEDGEN:1802616",
          "OMIM:619747",
          "UMLS:C5676917"
        ],
        "synonyms": [
          "CMD2F",
          "cardiomyopathy, dilated, 2F"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that is characterized by refractory ventricular arrhythmias and severe heart failure and that has material basis in homozygous mutation in the BAG5 gene on chromosome 14q32."
      },
      "child_count": 0,
      "reference_id": "MONDO:0030680"
    },
    {
      "id": 22097,
      "label": "cardiomyopathy, dilated, 2G",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081163",
          "GARD:0025652",
          "MEDGEN:1801983",
          "OMIM:619897",
          "UMLS:C5676995"
        ],
        "synonyms": [
          "CMD2G",
          "cardiomyopathy, dilated, 2G"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that is characterized by early-onset severe dilated cardiomyopathy that progresses rapidly to heart failure in the neonatal period without evidence of intervening hypertrophy and that has material basis in homozygous or compound heterozygous mutation in the LMOD2 gene on chromosome 7q31."
      },
      "child_count": 0,
      "reference_id": "MONDO:0030887"
    },
    {
      "id": 22279,
      "label": "cardiomyopathy, dilated, 2c",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081159",
          "GARD:0016305",
          "MEDGEN:1648379",
          "OMIM:618189",
          "UMLS:C4748647"
        ],
        "synonyms": [
          "CARDIOMYOPATHY, DILATED, 2C",
          "CMD2C"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ],
        "definition": "A dilated cardiomyopathy that is characterized by dilated cardiomyopathy of variable severity, with age of onset ranging from 2 to 20 years and that has material basis in homozygous or compound heterozygous mutation in the PPCS gene on chromosome 1p34."
      },
      "child_count": 0,
      "reference_id": "MONDO:0032592"
    },
    {
      "id": 25485,
      "label": "cardiomyopathy, dilated, 2H",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24709
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026714",
          "MEDGEN:1824069",
          "OMIM:620203",
          "UMLS:C5774296"
        ],
        "categories": [
          {
            "ref": "MONDO:0002081",
            "name": "musculoskeletal system disorder"
          },
          {
            "ref": "MONDO:0004995",
            "name": "cardiovascular disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0859358"
    }
  ],
  "roots": [
    {
      "id": 16878,
      "label": "familial dilated cardiomyopathy"
    }
  ]
}