{
  "id": 24826,
  "label": "postinfectious bronchiolitis obliterans",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0800119",
  "properties": {
    "xrefs": [
      "MEDGEN:1840786",
      "UMLS:C5830150"
    ],
    "synonyms": [
      "PIBO"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "An irreversible obstructive lung disease characterized by subepithelial inflammation and fibrotic narrowing of the bronchioles after lower respiratory tract infection during childhood, especially early childhood. Although diagnosis of PIBO should be confirmed by histopathology, it is generally based on history and clinical findings. Irreversible airway obstruction is demonstrated by decreased forced expiratory volume in 1 second with an absent bronchodilator response, and by mosaic perfusion, air trapping, and/or bronchiectasis on computed tomography images. However, lung function tests using spirometry are not feasible in young children, and most cases of PIBO develop during early childhood."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 4545,
      "label": "bronchiolitis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6971
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2942",
          "HP:0011950",
          "ICD9:466.19",
          "MEDGEN:14235",
          "MESH:D001988",
          "NCIT:C39658",
          "SCTID:4120002",
          "UMLS:C0006271"
        ],
        "synonyms": [
          "bronchiolitis",
          "bronchiolitis (disease)",
          "wheezy bronchitis",
          "RSV bronchiolitis",
          "viral bronchiolitis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "Inflammation of the bronchioles characterized by swelling of the bronchioles and mucus accumulation. It is usually caused by the respiratory syncytial virus and affects children. Signs and symptoms include coughing, wheezing, and shortness of breath."
      },
      "child_count": 6,
      "reference_id": "MONDO:0002465"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 4545,
      "label": "bronchiolitis"
    }
  ]
}