{
  "id": 25188,
  "label": "acute asthma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0850283",
  "properties": {
    "xrefs": [
      "DOID:0080810",
      "MEDGEN:578946",
      "UMLS:C0349790"
    ],
    "categories": [
      {
        "ref": "MONDO:0005087",
        "name": "respiratory system disorder"
      }
    ],
    "definition": "An asthma that is characterized by severe and sudden onset of increasing wheezing, airways closing, smooth muscle contraction, mucus plugging and lower airway edema that may be reversible upon treatment."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 6720,
      "label": "asthma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3582
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2841",
          "HP:0002099",
          "ICD10CM:J45",
          "ICD10WHO:J45",
          "ICD9:493",
          "ICD9:493.81",
          "ICD9:493.9",
          "MEDGEN:2109",
          "MESH:D001249",
          "NCIT:C28397",
          "SCTID:31387002",
          "UMLS:C0004096",
          "icd11.foundation:1656445230"
        ],
        "synonyms": [
          "chronic obstructive asthma",
          "chronic obstructive asthma with acute exacerbation",
          "chronic obstructive asthma with status asthmaticus",
          "exercise induced asthma",
          "exercise-induced asthma"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety."
      },
      "child_count": 8,
      "reference_id": "MONDO:0004979"
    }
  ],
  "children": [
    {
      "id": 25572,
      "label": "near-fatal asthma",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        25188
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080823",
          "MEDGEN:1673783",
          "UMLS:C5192201"
        ],
        "categories": [
          {
            "ref": "MONDO:0005087",
            "name": "respiratory system disorder"
          }
        ],
        "definition": "An acute asthma that is characterized by a respiratory arrest or arterial carbon dioxide tension greater than 50 mmHg, with or without altered consciousness, requiring mechanical ventilation."
      },
      "child_count": 0,
      "reference_id": "MONDO:0956977"
    }
  ],
  "roots": [
    {
      "id": 6720,
      "label": "asthma"
    }
  ]
}