{
  "id": 25509,
  "label": "ichthyosis hystrix",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0859383",
  "properties": {
    "xrefs": [
      "GARD:0026728",
      "MEDGEN:75527",
      "OMIMPS:146590",
      "UMLS:C0263580"
    ],
    "categories": [
      {
        "ref": "MONDO:0002051",
        "name": "integumentary system disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 16624,
      "label": "inherited ichthyosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        19130,
        23867
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0020261",
          "ICD10CM:Q80",
          "ICD9:757.1",
          "MEDGEN:797407",
          "MedDRA:10021202",
          "NANDO:1200609",
          "NANDO:2100283",
          "Orphanet:183435",
          "SCTID:13059002",
          "UMLS:C0856562"
        ],
        "synonyms": [
          "congenital ichthyosis of skin",
          "genetic ichthyosis",
          "hereditary ichthyosis (disease)",
          "inherited genetic ichthyosis",
          "congenital ichthyosis",
          "fish scale disease",
          "fish skin",
          "ichthyosis congenita"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Mendelian disorders of cornification affecting all or most of integument characterized by hyperkeratosis and/or scaling, caused by an inherited modification of the individual's genome."
      },
      "child_count": 26,
      "reference_id": "MONDO:0015947"
    }
  ],
  "children": [
    {
      "id": 9150,
      "label": "ichthyosis hystrix of Curth-Macklin",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        17595,
        25509
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0002954",
          "ICD9:757.39",
          "MEDGEN:326700",
          "MESH:C536088",
          "NORD:1281",
          "OMIM:146590",
          "Orphanet:79503",
          "SCTID:254170001",
          "UMLS:C1840296"
        ],
        "synonyms": [
          "Curth-Macklin type ichthyosis hystrix",
          "IHCM",
          "Ichthyosis Hystrix, Curth Macklin Type",
          "ichthyosis HYSTRIX, Curth-Macklin type",
          "ichthyosis histrix, curth-macklin type",
          "ichthyosis hystrix, Curth Macklin type",
          "ichthyosis hystrix, Curth-Macklin type"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ],
        "definition": "Ichthyosis hystrix of Curth-Macklin (IHCM) is a rare type of keratinopathic ichthyosis that is characterized by the presence of severe hyperkeratotic lesions and palmoplantar keratoderma (PPK)."
      },
      "child_count": 0,
      "reference_id": "MONDO:0007808"
    },
    {
      "id": 9151,
      "label": "ichthyosis histrix, Lambert type",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        25509
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0009497",
          "ICD9:757.39",
          "MEDGEN:98487",
          "MESH:C536087",
          "OMIM:146600",
          "Orphanet:79504",
          "SCTID:254174005",
          "UMLS:C0432311"
        ],
        "synonyms": [
          "ichthyosis hystrix gravior",
          "ichthyosis, Lambert type",
          "Lambert type ichthyosis",
          "porcupine Man"
        ],
        "categories": [
          {
            "ref": "MONDO:0002051",
            "name": "integumentary system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0007809"
    }
  ],
  "roots": [
    {
      "id": 16624,
      "label": "inherited ichthyosis"
    }
  ]
}