{
  "id": 25595,
  "label": "hereditary hemolytic uremic syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0957097",
  "properties": {
    "xrefs": [
      "GARD:0022330",
      "MEDGEN:1825935",
      "OMIMPS:235400",
      "Orphanet:576742",
      "UMLS:C5680355"
    ],
    "synonyms": [
      "genetic hemolytic uremic syndrome"
    ],
    "categories": [
      {
        "ref": "MONDO:0005570",
        "name": "hematologic disorder"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 2,
  "parents": [
    {
      "id": 3755,
      "label": "hemolytic-uremic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:12554",
          "GARD:0022233",
          "ICD10CM:D59.3",
          "ICD9:283.11",
          "MEDGEN:42403",
          "MESH:D006463",
          "NCIT:C75545",
          "Orphanet:544458",
          "SCTID:111407006",
          "UMLS:C0019061"
        ],
        "synonyms": [
          "HUS",
          "hemolytic uremic syndrome",
          "acute renal failure, thrombocytopenia, and microangiopathic hemolytic anaemia associated with distorted erythrocytes ('burr cells')",
          "acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells')"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Acute kidney injury associated with microangiopathic hemolytic anemia and thrombocytopenia."
      },
      "child_count": 2,
      "reference_id": "MONDO:0001549"
    },
    {
      "id": 20411,
      "label": "inherited blood coagulation disorder",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        3738,
        5714
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2214",
          "GARD:0020319",
          "MEDGEN:163105",
          "MESH:D025861",
          "Orphanet:183654",
          "UMLS:C0852077"
        ],
        "synonyms": [
          "coagulation disorder, hereditary",
          "coagulation disorder, inherited",
          "coagulation disorders, hereditary",
          "coagulation disorders, inherited",
          "hereditary blood coagulation disease",
          "hereditary blood coagulation disorders",
          "hereditary coagulation disorder",
          "hereditary coagulation disorders",
          "inherited blood coagulation disorders",
          "inherited coagulation disorder",
          "inherited coagulation disorders",
          "rare genetic coagulation disorder",
          "inherited blood coagulation disease"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "Hemorrhagic and thrombotic disorders that occur as a consequence of inherited abnormalities in blood coagulation."
      },
      "child_count": 78,
      "reference_id": "MONDO:0021181"
    }
  ],
  "children": [
    {
      "id": 16818,
      "label": "atypical hemolytic-uremic syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        5701,
        19495,
        25595
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0080301",
          "GARD:0008702",
          "MEDGEN:444141",
          "MESH:D065766",
          "NANDO:1200473",
          "NANDO:1200474",
          "NANDO:2200131",
          "NANDO:2200641",
          "NCIT:C123223",
          "NORD:822",
          "Orphanet:2134",
          "UMLS:C2931788"
        ],
        "synonyms": [
          "Atypical Hemolytic Uremic Syndrome",
          "D-HUS",
          "aHUS",
          "atypical HUS",
          "atypical hemolytic uremic syndrome",
          "hemolytic-uremic syndrome without diarrhea",
          "hemolytic-uremic syndrome without diarrhoea",
          "non-diarrhea-associated hemolytic uremic syndrome",
          "D-minus hemolytic uremic syndrome (D-HUS)",
          "HUS, atypical"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ],
        "definition": "A rare, genetic thrombotic microangiopathy due to dysregulation of the alternative complement pathway and characterized by the triad of hemolytic anemia, thrombocytopenia, and acute renal dysfunction."
      },
      "child_count": 16,
      "reference_id": "MONDO:0016244"
    },
    {
      "id": 25698,
      "label": "hemolytic uremic syndrome, atypical, 8, with rhizomelic short stature",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        25595
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0026853",
          "MEDGEN:1840221",
          "OMIM:301110",
          "UMLS:C5829585"
        ],
        "categories": [
          {
            "ref": "MONDO:0005570",
            "name": "hematologic disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0957495"
    }
  ],
  "roots": [
    {
      "id": 3755,
      "label": "hemolytic-uremic syndrome"
    },
    {
      "id": 20411,
      "label": "inherited blood coagulation disorder"
    }
  ]
}