{
  "id": 25718,
  "label": "Houge-Janssens syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0957553",
  "properties": {
    "xrefs": [
      "OMIMPS:616355"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      }
    ]
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 4370,
      "label": "syndromic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29379
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:225",
          "MEDGEN:11688",
          "MESH:D013577",
          "NCIT:C28193",
          "OGMS:0000086",
          "UMLS:C0039082"
        ],
        "synonyms": [
          "cluster, symptom",
          "clusters, symptom",
          "symptom cluster",
          "symptom clusters",
          "syndrome",
          "syndrome associated with disease or disorder",
          "syndromes",
          "syndromic disease",
          "syndromic disease or disorder"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ],
        "definition": "A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition."
      },
      "child_count": 1182,
      "reference_id": "MONDO:0002254"
    },
    {
      "id": 5714,
      "label": "hereditary disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29382
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:630",
          "EFO:0000508",
          "ICD9:799.89",
          "MEDGEN:5527",
          "MESH:D030342",
          "NCIT:C3101",
          "SCTID:32895009",
          "UMLS:C0019247"
        ],
        "synonyms": [
          "genetic condition",
          "genetic disease",
          "genetic disorder",
          "hereditary disease",
          "hereditary disease or disorder",
          "hereditary diseases",
          "inherited disease",
          "inherited genetic disease",
          "molecular disease",
          "Mendelian disease",
          "familial disorder",
          "inborn disorder"
        ],
        "definition": "A disease that is caused by genetic modifications where those modifications are inherited from a parent's genome."
      },
      "child_count": 1925,
      "reference_id": "MONDO:0003847"
    }
  ],
  "children": [
    {
      "id": 15600,
      "label": "Houge-Janssens syndrome 1",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        4427,
        16087,
        24323,
        25718
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070065",
          "GARD:0017802",
          "MEDGEN:1830493",
          "OMIM:616355",
          "Orphanet:457279",
          "UMLS:C5779996"
        ],
        "synonyms": [
          "MRD35",
          "autosomal dominant intellectual disability 35",
          "intellectual disability, autosomal dominant type 35",
          "intellectual disability-macrocephaly-hypotonia-behavioral abnormalities syndrome",
          "mental retardation, autosomal dominant type 35",
          "autosomal dominant non-syndromic intellectual disability 35",
          "intellectual disability, autosomal dominant 35",
          "mental retardation, autosomal dominant 35"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "An autosomal dominant intellectual developmental disorder that has material basis in an autosomal dominant mutation of the PPP2R5D gene on chromosome 6p21.1."
      },
      "child_count": 0,
      "reference_id": "MONDO:0014602"
    },
    {
      "id": 15603,
      "label": "Houge-Janssens syndrome 2",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        2903,
        16087,
        25718
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0070066",
          "GARD:0017803",
          "MEDGEN:899880",
          "OMIM:616362",
          "Orphanet:457284",
          "UMLS:C4225352"
        ],
        "synonyms": [
          "MRD36",
          "autosomal dominant intellectual disability 36",
          "intellectual disability, autosomal dominant type 36",
          "mental retardation, autosomal dominant type 36",
          "microcephaly-corpus callosum hypoplasia-intellectual disability-facial dysmorphism syndrome",
          "autosomal dominant non-syndromic intellectual disability 36",
          "intellectual disability, autosomal dominant 36",
          "mental retardation, autosomal dominant 36"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0014605"
    },
    {
      "id": 22371,
      "label": "Houge-Janssens syndrome 3",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        24226,
        25718
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1677130",
          "OMIM:618354",
          "UMLS:C5193048"
        ],
        "synonyms": [
          "NEDLBA",
          "neurodevelopmental disorder and language delay with or without structural brain abnormalities"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0032697"
    },
    {
      "id": 26220,
      "label": "Houge-Janssens syndrome 4",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        25718
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:1876484",
          "OMIM:621185",
          "UMLS:C6012718"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0978293"
    }
  ],
  "roots": [
    {
      "id": 4370,
      "label": "syndromic disease"
    },
    {
      "id": 5714,
      "label": "hereditary disease"
    }
  ]
}