{
  "id": 26295,
  "label": "juvenile neuronal ceroid lipofuscinosis 2",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:0979345",
  "properties": {
    "xrefs": [
      "Orphanet:699769"
    ],
    "synonyms": [
      "juvenile CLN2 disease"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ]
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 10041,
      "label": "neuronal ceroid lipofuscinosis 2",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16851
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0110726",
          "GARD:0003045",
          "MEDGEN:406281",
          "NANDO:1200153",
          "NANDO:2201242",
          "NCIT:C85864",
          "OMIM:204500",
          "Orphanet:228349",
          "UMLS:C1876161"
        ],
        "synonyms": [
          "late infantile neuronal ceroid lipofuscinosis",
          "CLN2",
          "TPP1 neuronal ceroid lipofuscinosis",
          "ceroid lipofuscinosis, neuronal, type 2",
          "neuronal ceroid lipofuscinosis caused by mutation in TPP1",
          "neuronal ceroid lipofuscinosis type 2",
          "CLN2 disease",
          "CLN2 disease, juvenile (subtype)",
          "CLN2 disease, late infantile (subtype)",
          "Jansky-Bielschowsky disease",
          "ceroid lipofuscinosis, neuronal, 2",
          "ceroid lipofuscinosis, neuronal, 2, variable Age at onset",
          "neuronal ceroid lipofuscinosis, late infantile"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A condition associated with mutation(s) in the TPP1 gene, encoding tripeptidyl-peptidase- 1. The condition is one of a group of genetically heterogeneous neurodegenerative disorders, characterized by accumulation of intracellular lipopigments."
      },
      "child_count": 3,
      "reference_id": "MONDO:0008769"
    },
    {
      "id": 19123,
      "label": "juvenile neuronal ceroid lipofuscinosis",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        16851,
        19753
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050756",
          "GARD:0004938",
          "MedDRA:10052073",
          "NANDO:1200154",
          "NANDO:2201243",
          "Orphanet:79264",
          "SCTID:61663001",
          "icd11.foundation:1716107919"
        ],
        "synonyms": [
          "JNCL",
          "Spielmeyer-Vogt disease",
          "batten disease",
          "juvenile NCL",
          "juvenile neuronal ceroid lipofuscinosis"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A genetically heterogeneous group of neuronal ceroid lipofuscinoses (NCLs) typically characterized by onset at early school age with vision loss due to retinopathy, seizures and the decline of mental and motor capacities."
      },
      "child_count": 16,
      "reference_id": "MONDO:0019262"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 10041,
      "label": "neuronal ceroid lipofuscinosis 2"
    },
    {
      "id": 19123,
      "label": "juvenile neuronal ceroid lipofuscinosis"
    }
  ]
}