{
  "id": 26452,
  "label": "pediatric high-grade glioma",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:1010030",
  "properties": {
    "xrefs": [
      "GARD:0027222",
      "MEDGEN:1861427",
      "NCIT:C202298",
      "UMLS:C5908419"
    ],
    "synonyms": [
      "childhood malignant glioma",
      "pHGG"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A malignant high-grade glioma that occurs during childhood in the central nervous system."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 8005,
      "label": "childhood malignant neoplasm",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6733,
        20320
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "EFO:1000654",
          "MEDGEN:82962",
          "NCIT:C4005",
          "UMLS:C0278704"
        ],
        "synonyms": [
          "childhood cancer",
          "childhood malignant neoplasm",
          "childhood neoplasm, malignant",
          "malignant childhood neoplasm",
          "malignant childhood tumor",
          "malignant childhood tumour",
          "malignant paediatric neoplasm",
          "malignant paediatric tumour",
          "malignant pediatric neoplasm",
          "malignant pediatric tumor",
          "paediatric cancer",
          "pediatric cancer",
          "malignant neoplasm"
        ],
        "definition": "A malignant tumor that occurs in children. Representative examples include soft tissue and bone sarcomas (e.g. osteosarcoma) and embryonal neoplasms (e.g. hepatoblastoma and rhabdoid tumor)."
      },
      "child_count": 60,
      "reference_id": "MONDO:0006517"
    },
    {
      "id": 24071,
      "label": "malignant glioma",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4753,
        20078,
        20287
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:3070",
          "GARD:0026148",
          "ICDO:9380/3",
          "MEDGEN:107826",
          "MedDRA:10018338",
          "NCIT:C4822",
          "UMLS:C0555198"
        ],
        "synonyms": [
          "glioma",
          "neuroglial tumor",
          "neuroglial tumour",
          "glial cell tumour",
          "glioma, malignant",
          "high grade glioma",
          "high-grade glioma",
          "malignant glial neoplasm",
          "malignant glial tumor",
          "malignant glial tumour",
          "malignant glioma",
          "malignant neuroglial neoplasm",
          "malignant neuroglial tumor",
          "malignant neuroglial tumour"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A grade III or grade IV glioma arising from the central nervous system. This category includes glioblastoma, anaplastic astrocytoma, anaplastic ependymoma, anaplastic oligodendroglioma, and anaplastic oligoastrocytoma."
      },
      "child_count": 36,
      "reference_id": "MONDO:0100342"
    }
  ],
  "children": [
    {
      "id": 25253,
      "label": "diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        26452
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0081277",
          "GARD:0026635",
          "MEDGEN:1808288",
          "NCIT:C185467",
          "UMLS:C5669918"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A high grade glioma that is characterized by the absence of histone H3, IDH1, and IDH2 mutations."
      },
      "child_count": 0,
      "reference_id": "MONDO:0858939"
    }
  ],
  "roots": [
    {
      "id": 8005,
      "label": "childhood malignant neoplasm"
    },
    {
      "id": 24071,
      "label": "malignant glioma"
    }
  ]
}