{
  "id": 29255,
  "label": "myelin oligodendrocyte glycoprotein antibody-associated disease",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:1040024",
  "properties": {
    "xrefs": [
      "MEDGEN:1813985",
      "UMLS:C5554054"
    ],
    "categories": [
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "A demyelinating disease of the central nervous system characterized by the presence of a demyelinating event (optic neuritis, myelitis, acute/multiphasic encephalomyelitis, cerebral or polyfocal deficits, brainstem or cerebellar deficits, and/or cerebral cortical encephalitis), a positive myelin oligodendrocyte glycorotein-IgG test, and exclusion of an alternative diagnosis like MS."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 4,
  "parents": [
    {
      "id": 20199,
      "label": "demyelinating disease of central nervous system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4626
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD10CM:G35-G37",
          "ICD9:341.8",
          "ICD9:341.9",
          "MEDGEN:3719",
          "NCIT:C34526",
          "SCTID:6118003",
          "UMLS:C0011302"
        ],
        "synonyms": [
          "demyelinating CNS disease",
          "demyelinating disease central nervous system (CNS)",
          "demyelinating disease of central nervous system",
          "demyelinating disorder of central nervous system",
          "demyelinating disorders of the central nervous system"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "Any condition in which there is degeneration of the myelin sheath that covers the nerves of the central nervous system."
      },
      "child_count": 2,
      "reference_id": "MONDO:0020800"
    },
    {
      "id": 20399,
      "label": "inflammatory disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29380
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "ICD9:799.89",
          "MEDGEN:452939",
          "NCIT:C93210",
          "SCTID:128139000",
          "UMLS:C1290884"
        ],
        "synonyms": [
          "anatomical structure inflammation",
          "inflammation of anatomical structure",
          "inflammatory disease",
          "inflammatory disorder"
        ],
        "definition": "A disease involving a pathogenic inflammatory response in the anatomical structure."
      },
      "child_count": 94,
      "reference_id": "MONDO:0021166"
    }
  ],
  "children": [
    {
      "id": 22883,
      "label": "neuromyelitis optica spectrum disorder with anti-MOG antibodies",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        18986,
        29255
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022373",
          "MEDGEN:1843203",
          "Orphanet:592856",
          "UMLS:C5680296",
          "icd11.foundation:605048789"
        ],
        "synonyms": [
          "NMOSD with anti-MOG antibodies",
          "Neuromyelitis optica spectrum disorder with anti-myelin oligodendrocyte glycoprotein antibodies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035664"
    },
    {
      "id": 22885,
      "label": "acute transverse myelitis with anti-MOG antibodies",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        16205,
        29255
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022375",
          "ICD10CM:G37.3",
          "MEDGEN:1842662",
          "Orphanet:592873",
          "UMLS:C5680298"
        ],
        "synonyms": [
          "Acute transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035666"
    },
    {
      "id": 22887,
      "label": "isolated optic neuritis with anti-MOG antibodies",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        23390,
        29255
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022377",
          "Orphanet:592888"
        ],
        "synonyms": [
          "Isolated optic neuritis with anti-myelin oligodendrocyte glycoprotein antibodies"
        ],
        "categories": [
          {
            "ref": "MONDO:0002022",
            "name": "disorder of orbital region"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          },
          {
            "ref": "MONDO:0024458",
            "name": "disorder of visual system"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035668"
    },
    {
      "id": 22888,
      "label": "acute disseminated encephalomyelitis with anti-MOG antibodies",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        19214,
        29255
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0022378",
          "ICD10CM:G04.0",
          "MEDGEN:1842363",
          "Orphanet:592894",
          "UMLS:C5680301"
        ],
        "synonyms": [
          "ADEM with anti-MOG antibodies",
          "Acute disseminated encephalomyelitis with anti-myelin oligodendrocyte glycoprotein antibodies"
        ],
        "categories": [
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ]
      },
      "child_count": 0,
      "reference_id": "MONDO:0035669"
    }
  ],
  "roots": [
    {
      "id": 20199,
      "label": "demyelinating disease of central nervous system"
    },
    {
      "id": 20399,
      "label": "inflammatory disease"
    }
  ]
}