{
  "id": 29340,
  "label": "pediatric acute-onset neuropsychiatric syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:1060178",
  "properties": {
    "xrefs": [
      "GARD:0028179",
      "MEDGEN:1673298",
      "UMLS:C5197301"
    ],
    "synonyms": [
      "PANS"
    ],
    "categories": [
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      },
      {
        "ref": "MONDO:0005071",
        "name": "nervous system disorder"
      }
    ],
    "definition": "An autoimmune disorder that involves a constellation of psychiatric and neurologic symptoms that present simultaneously and in rapid onset, the cause or causes of which are unknown. Although the cause is still under investigation, the manifestations may follow a recent infection."
  },
  "isLeaf": false,
  "isRoot": false,
  "child_count": 1,
  "parents": [
    {
      "id": 4981,
      "label": "autoimmune disorder of the nervous system",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        6799,
        8586
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:438",
          "MEDGEN:155946",
          "MESH:D020274",
          "NCIT:C99383",
          "UMLS:C0751871"
        ],
        "synonyms": [
          "autoimmune disease of nervous system",
          "autoimmune disease, neurologic",
          "autoimmune diseases, nervous system",
          "autoimmune diseases, neurologic",
          "autoimmune disorders of the nervous system",
          "autoimmune disorders, nervous system",
          "autoimmune nervous system diseases",
          "autoimmune nervous system disorder",
          "disease, neurologic autoimmune",
          "diseases, neurologic autoimmune",
          "immune diseases, nervous system",
          "immune disorders, nervous system",
          "nervous system autoimmune disease",
          "nervous system autoimmune diseases",
          "nervous system hypersensitivity reaction type II disease",
          "nervous system immune diseases",
          "nervous system immune disorders",
          "neurologic autoimmune disease",
          "neurologic autoimmune diseases"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "A disorder characterized by the degeneration of the nervous system due to autoimmunity. Representative examples include multiple sclerosis, Guillain-Barre syndrome, and myasthenia gravis."
      },
      "child_count": 8,
      "reference_id": "MONDO:0002977"
    },
    {
      "id": 24405,
      "label": "idiopathic disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        29381
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "MEDGEN:548250",
          "UMLS:C0277553"
        ],
        "synonyms": [
          "idiopathic disorder"
        ],
        "definition": "A disease or disorder for which the cause is of uncertain or unknown."
      },
      "child_count": 79,
      "reference_id": "MONDO:0700007"
    }
  ],
  "children": [
    {
      "id": 18934,
      "label": "PANDAS",
      "isLeaf": true,
      "isRoot": false,
      "parents": [
        29340
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "GARD:0007312",
          "MEDGEN:419798",
          "MESH:C537163",
          "Orphanet:66624",
          "UMLS:C2931429"
        ],
        "synonyms": [
          "paediatric autoimmune disorders associated with Streptococcus infections",
          "paediatric autoimmune neuropsychiatric disorders associated with Streptococcus infections",
          "pediatric autoimmune disorders associated with Streptococcus infections",
          "pediatric autoimmune neuropsychiatric disorders associated with Streptococcus infections",
          "paediatric autoimmune neuropsychiatric disorder associated with Streptococcus",
          "paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections",
          "pediatric autoimmune neuropsychiatric disorder associated with Streptococcus",
          "pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections"
        ],
        "categories": [
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          },
          {
            "ref": "MONDO:0005071",
            "name": "nervous system disorder"
          }
        ],
        "definition": "PANDAS is an acronym for Pediatric Autoimmune Neuropsychiatric Disorders Associated with a group A beta-hemolytic Streptococcal infection and applied to a subgroup of children with obsessive-compulsive disorder (OCD) and/or tic disorders."
      },
      "child_count": 0,
      "reference_id": "MONDO:0019020"
    }
  ],
  "roots": [
    {
      "id": 4981,
      "label": "autoimmune disorder of the nervous system"
    },
    {
      "id": 24405,
      "label": "idiopathic disease"
    }
  ]
}