{
  "id": 29376,
  "label": "cystic fibrosis-related diabetes",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:7770003",
  "properties": {
    "xrefs": [
      "ICD10CM:E13"
    ],
    "synonyms": [
      "CF-related diabetes",
      "CFRD"
    ],
    "categories": [
      {
        "ref": "MONDO:0004335",
        "name": "digestive system disorder"
      },
      {
        "ref": "MONDO:0005151",
        "name": "endocrine system disorder"
      }
    ],
    "definition": "A form of diabetes mellitus unique to individuals with cystic fibrosis (CF), arising primarily from progressive fibrotic destruction of the pancreas leading to insulin deficiency, with additional contributions from insulin resistance. CFRD affects approximately 20% of adolescents and 40-50% of adults with CF. It shares features with both type 1 and type 2 diabetes but is a distinct clinical entity with its own diagnostic criteria and management guidelines."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 6752,
      "label": "diabetes mellitus",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4104,
        4915
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:9351",
          "EFO:0000400",
          "HP:0000819",
          "ICD10CM:E08-E13",
          "ICD10WHO:E10-E14",
          "ICD9:250",
          "MEDGEN:8350",
          "MESH:D003920",
          "NANDO:2100157",
          "NANDO:2100158",
          "NCIT:C2985",
          "SCTID:73211009",
          "UMLS:C0011849",
          "icd11.foundation:465177735"
        ],
        "synonyms": [
          "DM",
          "diabetes",
          "diabetes mellitus",
          "diabetes mellitus (disease)"
        ],
        "categories": [
          {
            "ref": "MONDO:0004335",
            "name": "digestive system disorder"
          },
          {
            "ref": "MONDO:0005151",
            "name": "endocrine system disorder"
          }
        ],
        "definition": "A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization."
      },
      "child_count": 16,
      "reference_id": "MONDO:0005015"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 6752,
      "label": "diabetes mellitus"
    }
  ]
}