{
  "id": 29397,
  "label": "familial antiphospholipid syndrome",
  "model": {
    "label": "Mondo Disease Ontology (MONDO)",
    "source": 0
  },
  "type_id": 0,
  "reference_id": "MONDO:8000014",
  "properties": {
    "xrefs": [
      "GARD:0027038",
      "MEDGEN:419641",
      "MESH:C531622",
      "OMIM:107320",
      "UMLS:C2930802"
    ],
    "synonyms": [
      "Hughes syndrome",
      "antiphospholipid syndrome, familial"
    ],
    "categories": [
      {
        "ref": "MONDO:0002254",
        "name": "syndromic disease"
      },
      {
        "ref": "MONDO:0005046",
        "name": "immune system disorder"
      }
    ],
    "definition": "Autosomal dominant form of antiphospholipid syndrome."
  },
  "isLeaf": true,
  "isRoot": false,
  "child_count": 0,
  "parents": [
    {
      "id": 2903,
      "label": "autosomal dominant disease",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        2905
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:0050736",
          "ICD9:758.5",
          "MEDGEN:539206",
          "SCTID:11164009",
          "UMLS:C0265385"
        ],
        "synonyms": [
          "autosomal dominant disease or disorder",
          "autosomal dominant hereditary disorder",
          "autosomal dominant inherited disorder",
          "disease or disorder, autosomal dominant",
          "disease, autosomal dominant"
        ],
        "definition": "Autosomal dominant form of disease."
      },
      "child_count": 192,
      "reference_id": "MONDO:0000426"
    },
    {
      "id": 29393,
      "label": "antiphospholipid syndrome",
      "isLeaf": false,
      "isRoot": false,
      "parents": [
        4370,
        8586
      ],
      "type_id": 0,
      "properties": {
        "xrefs": [
          "DOID:2988",
          "EFO:0002689",
          "GARD:0005824",
          "ICD10CM:D68.61",
          "ICD9:279.49",
          "MEDGEN:38834",
          "MESH:D016736",
          "NCIT:C61283",
          "Orphanet:80",
          "SCTID:26843008",
          "UMLS:C0085278",
          "icd11.foundation:1173370808"
        ],
        "synonyms": [
          "Hughes syndrome",
          "antiphospholipid antibody syndrome",
          "antiphospholipid syndrome",
          "familial lupus anticoagulant",
          "lupus anticoagulant, familial"
        ],
        "categories": [
          {
            "ref": "MONDO:0002254",
            "name": "syndromic disease"
          },
          {
            "ref": "MONDO:0005046",
            "name": "immune system disorder"
          }
        ],
        "definition": "A disorder caused by the presence of autoantibodies directed against phospholipids, causing a hypercoaguable state, which may result in blood clots, stroke, heart attack, and in women, significant pregnancy-related complications, including miscarriage and still birth. The syndrome is often associated with other autoimmune disorders, most commonly lupus erythematosus, and infections, including syphilis and Lyme disease."
      },
      "child_count": 8,
      "reference_id": "MONDO:8000010"
    }
  ],
  "children": [],
  "roots": [
    {
      "id": 2903,
      "label": "autosomal dominant disease"
    },
    {
      "id": 29393,
      "label": "antiphospholipid syndrome"
    }
  ]
}