[ { "phenotype_id": "PH1019", "phenotype_version_id": 2197, "name": "Thrombophilia", "definition": "Code type is set to 1 for incident events, and 0 for prevalent events.\n\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, and thrombocytopenic events: whole population cohort study in 46 million adults in England CVD-COVID-UK consortium, William N Whiteley, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Venexia Walker, Rachel Denholm, Ashley Akbari, Efosa Omigie, Sam Hollings, Emanuele Di Angelantonio, Spiros Denaxas, Angela Wood, Jonathan A C Sterne, Cathie Sudlow medRxiv 2021.08.18.21262222; doi: https://doi.org/10.1", "primary": true } ], "validation": "", "citation_requirements": "", "created": "2022-05-09T08:02:40.866169Z", "author": "CVD-COVID-UK consortium, William N Whiteley, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Venexia Walker, Rachel Denholm, Ashley Akbari, Efosa Omigie, Sam Hollings, Emanuele Di Angelantonio, Spiros Denaxas, Angela Wood, Jonathan A C Sterne, Cathie Sudlow", "collections": [ { "name": "BHF Data Science Centre", "value": 20 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": { "id": 13, "slug": "bhf-data-science-centre", "name": "BHF Data Science Centre" }, "world_access": 1, "updated": "2022-05-17T21:23:39.847575Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "trials": null, "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "Trusted Research Environments for CVD-COVID-UK / COVID-IMPACT", "value": 37, "uid": "7e5f0247-f033-4f98-aed3-3d7422b9dc6d", "url": "https://healthdatagateway.org/en/dataset/1379", "datasource_id": 1379 }, { "name": "GPES Data for Pandemic Planning and Research (COVID-19)", "value": 1, "uid": "c7eed372-9f1e-467e-8a37-948f4de5abc4", "url": "https://healthdatagateway.org/en/dataset/874", "datasource_id": 874 }, { "name": "Hospital Episode Statistics Admitted Patient Care", "value": 2, "uid": "6599230a-df54-4615-937c-d724d239491f", "url": "https://healthdatagateway.org/en/dataset/875", "datasource_id": 875 }, { "name": "Secondary Uses Services Payment By Results", "value": 38, "uid": "d4c2361e-556f-4812-b17e-7f371b04c0d2", "url": "https://healthdatagateway.org/en/dataset/851", "datasource_id": 851 }, { "name": "Civil Registration - Deaths", "value": 3, "uid": "b9009bc5-b7a6-4036-9d4b-a5133c0b14a3", "url": "https://healthdatagateway.org/en/dataset/877", "datasource_id": 877 } ], "endorsements": null, "project_name": "CCU002_02", "coding_system": [ { "name": "ICD10 codes", "value": 4 }, { "name": "SNOMED CT codes", "value": 9 } ], "corresp_author": null, "event_date_range": "08/12/2020 - 18/03/2021", "concept_information": [ { "concept_id": 2905, "concept_version_id": 7425, "concept_name": "CCU002_02 Thrombophilia - Phenotypes - England primary care EHR: Thrombophilia diagnosis", "coding_system": { "id": 9, "name": "SNOMED CT codes", "description": "SNOMED CT codes" }, "phenotype_id": "PH1019", "phenotype_version_id": 2197, "phenotype_name": "Thrombophilia", "code_attribute_header": [ "terminology", "code_type" ], "codes": [ { "code": "234467004", "description": "Thrombophilia", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "439001009", "description": "Acquired thrombophilia", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "439002002", "description": "Thrombophilia due to acquired protein C deficiency", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "439125003", "description": "Thrombophilia due to acquired protein S deficiency", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "439126002", "description": "Thrombophilia due to acquired antithrombin III deficiency", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "439698008", "description": "Primary thrombophilia", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "441079006", "description": "Thrombophilia due to antiphospholipid antibody", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "441697004", "description": "Thrombophilia associated with pregnancy", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "441762006", "description": "Thrombophilia due to immobilisation", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "441882000", "description": "History of thrombophilia", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "441945008", "description": "Thrombophilia due to trauma", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "441946009", "description": "Thrombophilia due to myeloproliferative disorder", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "441990004", "description": "Thrombophilia due to paroxysmal nocturnal haemoglobinuria", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "442078001", "description": "Thrombophilia due to malignant neoplasm", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "442121006", "description": "Thrombophilia due to vascular anomaly", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "442197003", "description": "Thrombophilia caused by drug therapy", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "442363001", "description": "Thrombophilia caused by vascular device", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "442654007", "description": "Thrombophilia caused by hormone therapy", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "442760001", "description": "Thrombophilia caused by antineoplastic agent therapy", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } }, { "code": "783250007", "description": "Hereditary thrombophilia due to congenital histidine-rich (poly-L) glycoprotein deficiency", "attributes": { "terminology": "SNOMEDCT", "code_type": "1.0" } } ] }, { "concept_id": 2906, "concept_version_id": 7426, "concept_name": "CCU002_02 Thrombophilia - Phenotypes - England hospitalization EHR: Thrombophilia diagnosis", "coding_system": { "id": 4, "name": "ICD10 codes", "description": "ICD10 Codes" }, "phenotype_id": "PH1019", "phenotype_version_id": 2197, "phenotype_name": "Thrombophilia", "code_attribute_header": [ "terminology", "code_type" ], "codes": [ { "code": "D68.5", "description": "Primary thrombophilia", "attributes": { "terminology": "ICD10", "code_type": "1.0" } }, { "code": "D68.6", "description": "Other thrombophilia", "attributes": { "terminology": "ICD10", "code_type": "1.0" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/rjpg-5a41", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 2, "name": "BHF Data Science Centre Phenotype", "description": "BHF Data Science Centre Phenotype definitions that describe a list of clinical codes, algorithms using clinical codes, or set of clinical trials. Visit the BHF Data Science Centre website to learn more: https://bhfdatasciencecentre.org", "version_id": 1 }, "versions": [ { "version_id": 2197, "version_name": "Thrombophilia", "version_date": "2022-05-17T21:23:40.151185Z", "is_published": true, "is_latest": true }, { "version_id": 2117, "version_name": "Thrombophilia", "version_date": "2022-05-09T08:02:40.915122Z", "is_published": true, "is_latest": false } ] } ]