[
  {
    "phenotype_id": "PH110",
    "phenotype_version_id": 220,
    "name": "Autism and Asperger's syndrome",
    "definition": "At the specified date, a patient is defined as having had 'Autism and Asperger's syndrome' and Asperger's syndrome IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:\n\n\nPrimary care\n\n\n1. 'Autism and Asperger's syndrome' and Asperger's syndrome diagnosis or history of diagnosis during a consultation \n\nOR\nSecondary care\n\n\n1. ALL diagnoses of 'Autism and Asperger's syndrome' and Asperger's syndrome or history of diagnosis during a hospitalization\n\n\n\n\n\n\n\n\n\n\n\n\n",
    "implementation": "",
    "publications": [
      {
        "doi": "10.1016/S2589-7500(19)30012-3",
        "details": "Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3"
      }
    ],
    "validation": "",
    "citation_requirements": "",
    "created": "2021-10-06T16:03:30.148026Z",
    "author": "Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A",
    "collections": [
      {
        "name": "CALIBER",
        "value": 21
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2021-10-06T16:03:30.148055Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "ontology": null,
    "phenoflowid": "https://kclhi.org/phenoflow/workflows/github.com/phenoflow/Autism-and-Aspergers-syndrome---bbf4c830-1762-11ef-9de4-4d4ea830ad16/blob/read-potential-cases-fhir/Autism-and-Aspergers-syndrome.cwl",
    "data_sources": [
      {
        "name": "CPRD GOLD",
        "value": 5,
        "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f",
        "url": "https://healthdatagateway.org/en/dataset/694",
        "datasource_id": 694
      },
      {
        "name": "HES Admitted Patient Care data for CPRD GOLD",
        "value": 9,
        "uid": "4bcf64a6-f404-4ef4-ae6e-172512ab5f43",
        "url": "https://healthdatagateway.org/en/dataset/674",
        "datasource_id": 674
      }
    ],
    "coding_system": [
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v2",
        "value": 5
      },
      {
        "name": "Med codes",
        "value": 8
      }
    ],
    "event_date_range": "01/01/1999 - 01/07/2016",
    "concept_information": [
      {
        "concept_id": 995,
        "concept_version_id": 3129,
        "concept_name": "Autism and Asperger's syndrome - Primary care",
        "coding_system": {
          "id": 5,
          "name": "Read codes v2",
          "description": "Read codes v2"
        },
        "phenotype_id": "PH110",
        "phenotype_version_id": 220,
        "phenotype_name": "Autism and Asperger's syndrome",
        "code_attribute_header": [
          "Disease",
          "Medcode",
          "Category"
        ],
        "codes": [
          {
            "code": "E140.00",
            "description": "Infantile autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "22098.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "E140000",
            "description": "Active infantile autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "63251.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "E140100",
            "description": "Residual infantile autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "69016.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "E140.11",
            "description": "Kanner's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "43444.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "E140.12",
            "description": "Autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "1276.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "E140.13",
            "description": "Childhood autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "7302.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "E140z00",
            "description": "Infantile autism NOS",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "36662.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "Eu84000",
            "description": "[X]Childhood autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "3637.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "Eu84011",
            "description": "[X]Autistic disorder",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "9982.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "Eu84012",
            "description": "[X]Infantile autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "50337.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "Eu84014",
            "description": "[X]Kanner's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "110478.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "Eu84100",
            "description": "[X]Atypical autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "24044.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "Eu84112",
            "description": "[X]Mental retardation with autistic features",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "34174.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "Eu84500",
            "description": "[X]Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "2950.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "Eu84511",
            "description": "[X]Autistic psychopathy",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "51375.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "Eu84z11",
            "description": "[X]Autistic spectrum disorder",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Medcode": "42941.0",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          }
        ]
      },
      {
        "concept_id": 996,
        "concept_version_id": 3131,
        "concept_name": "Autism and Asperger's syndrome - Primary care",
        "coding_system": {
          "id": 8,
          "name": "Med codes",
          "description": "Med codes"
        },
        "phenotype_id": "PH110",
        "phenotype_version_id": 220,
        "phenotype_name": "Autism and Asperger's syndrome",
        "code_attribute_header": [
          "Disease",
          "ReadcodeDescr",
          "Readcode"
        ],
        "codes": [
          {
            "code": "110478.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "[X]Kanner's syndrome",
              "Readcode": "Eu84014"
            }
          },
          {
            "code": "1276.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "Autism",
              "Readcode": "E140.12"
            }
          },
          {
            "code": "22098.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "Infantile autism",
              "Readcode": "E140.00"
            }
          },
          {
            "code": "24044.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "[X]Atypical autism",
              "Readcode": "Eu84100"
            }
          },
          {
            "code": "2950.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "[X]Asperger's syndrome",
              "Readcode": "Eu84500"
            }
          },
          {
            "code": "34174.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "[X]Mental retardation with autistic features",
              "Readcode": "Eu84112"
            }
          },
          {
            "code": "3637.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "[X]Childhood autism",
              "Readcode": "Eu84000"
            }
          },
          {
            "code": "36662.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "Infantile autism NOS",
              "Readcode": "E140z00"
            }
          },
          {
            "code": "42941.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "[X]Autistic spectrum disorder",
              "Readcode": "Eu84z11"
            }
          },
          {
            "code": "43444.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "Kanner's syndrome",
              "Readcode": "E140.11"
            }
          },
          {
            "code": "50337.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "[X]Infantile autism",
              "Readcode": "Eu84012"
            }
          },
          {
            "code": "51375.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "[X]Autistic psychopathy",
              "Readcode": "Eu84511"
            }
          },
          {
            "code": "63251.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "Active infantile autism",
              "Readcode": "E140000"
            }
          },
          {
            "code": "69016.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "Residual infantile autism",
              "Readcode": "E140100"
            }
          },
          {
            "code": "7302.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "Childhood autism",
              "Readcode": "E140.13"
            }
          },
          {
            "code": "9982.0",
            "description": "Diagnosis of Autism and Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "ReadcodeDescr": "[X]Autistic disorder",
              "Readcode": "Eu84011"
            }
          }
        ]
      },
      {
        "concept_id": 997,
        "concept_version_id": 3133,
        "concept_name": "Autism and Asperger's syndrome - Secondary care - Diagnoses",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH110",
        "phenotype_version_id": 220,
        "phenotype_name": "Autism and Asperger's syndrome",
        "code_attribute_header": [
          "Disease",
          "Category"
        ],
        "codes": [
          {
            "code": "F84.0",
            "description": "Childhood autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "F84.1",
            "description": "Atypical autism",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          },
          {
            "code": "F84.5",
            "description": "Asperger's syndrome",
            "attributes": {
              "Disease": "Autism and Asperger's syndrome",
              "Category": "Diagnosis of Autism and Asperger's syndrome"
            }
          }
        ]
      }
    ],
    "status": 2,
    "doi": "https://doi.org/10.48533/49b6-3264",
    "is_deleted": null,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 1,
      "name": "Clinical-Coded Phenotype",
      "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 220,
        "version_name": "Autism and Asperger's syndrome",
        "version_date": "2021-10-06T16:03:30.175129Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]